BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 19447222)

  • 1. Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines.
    Kühne A; Tzvetkov MV; Hagos Y; Lage H; Burckhardt G; Brockmöller J
    Biochem Pharmacol; 2009 Jul; 78(1):45-53. PubMed ID: 19447222
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan.
    Kühne A; Kaiser R; Schirmer M; Heider U; Muhlke S; Niere W; Overbeck T; Hohloch K; Trümper L; Sezer O; Brockmöller J
    Pharmacogenet Genomics; 2007 Jul; 17(7):505-17. PubMed ID: 17558306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of xenobiotic efflux transporters in resistance to vincristine.
    Huang RS; Murry DJ; Foster DR
    Biomed Pharmacother; 2008 Feb; 62(2):59-64. PubMed ID: 17583464
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combination therapy and noninvasive imaging with a dual therapeutic vector expressing MDR1 short hairpin RNA and a sodium iodide symporter.
    Park SY; Kwak W; Thapa N; Jung MY; Nam JO; So IS; Kim SY; Yoo J; Lee J; Kim IS
    J Nucl Med; 2008 Sep; 49(9):1480-8. PubMed ID: 18703598
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells.
    Hira A; Watanabe H; Maeda Y; Yokoo K; Sanematsu E; Fujii J; Sasaki J; Hamada A; Saito H
    Biochem Pharmacol; 2008 Feb; 75(4):973-80. PubMed ID: 18054347
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conferone from Ferula schtschurowskiana enhances vinblastine cytotoxicity in MDCK-MDR1 cells by competitively inhibiting P-glycoprotein transport.
    Barthomeuf C; Demeule M; Grassi J; Saidkhodjaev A; Beliveau R
    Planta Med; 2006 Jun; 72(7):634-9. PubMed ID: 16739070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. P-Glycoprotein expression in human retinal pigment epithelium cell lines.
    Constable PA; Lawrenson JG; Dolman DE; Arden GB; Abbott NJ
    Exp Eye Res; 2006 Jul; 83(1):24-30. PubMed ID: 16530756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antimultidrug-resistant effect and mechanism of a novel CA-4 analogue MZ3 on leukemia cells.
    Xu D; Fang L; Zhu Q; Hu Y; He Q; Yang B
    Pharmazie; 2008 Jul; 63(7):528-33. PubMed ID: 18717489
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vinblastine-induced Caco-2 cell lines.
    Siissalo S; Laitinen L; Koljonen M; Vellonen KS; Kortejärvi H; Urtti A; Hirvonen J; Kaukonen AM
    Eur J Pharm Biopharm; 2007 Sep; 67(2):548-54. PubMed ID: 17475454
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lentivirus-mediated RNA interference reversing the drug-resistance in MDR1 single-factor resistant cell line K562/MDR1.
    Ye X; Liu T; Gong Y; Zheng B; Meng W; Leng Y
    Leuk Res; 2009 Aug; 33(8):1114-9. PubMed ID: 19036441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of P-glycoprotein and multidrug resistance proteins in rat kidney and intestinal cell lines.
    van de Water FM; Boleij JM; Peters JG; Russel FG; Masereeuw R
    Eur J Pharm Sci; 2007 Jan; 30(1):36-44. PubMed ID: 17088052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells.
    Kaneko S; Ando A; Okuda-Ashitaka E; Maeda M; Furuta K; Suzuki M; Matsumura M; Ito S
    Invest Ophthalmol Vis Sci; 2007 Jan; 48(1):464-71. PubMed ID: 17197568
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line.
    Klamt F; Passos DT; Castro MA; Gelain DP; Grivicich I; Moreira JC
    Toxicol In Vitro; 2008 Jun; 22(4):873-8. PubMed ID: 18282684
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alkylator resistance in human B lymphoid cell lines: (1). Melphalan accumulation, cytotoxicity, interstrand-DNA-crosslinks, cell cycle analysis, and glutathione content in the melphalan-sensitive B-lymphocytic cell line (WIL2) and in the melphalan-resistant B-CLL cell line (WSU-CLL).
    Pu Q; Bianchi P; Bezwoda WR
    Anticancer Res; 2000; 20(4):2561-8. PubMed ID: 10953327
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intestinal drug transporter expression and the impact of grapefruit juice in humans.
    Glaeser H; Bailey DG; Dresser GK; Gregor JC; Schwarz UI; McGrath JS; Jolicoeur E; Lee W; Leake BF; Tirona RG; Kim RB
    Clin Pharmacol Ther; 2007 Mar; 81(3):362-70. PubMed ID: 17215845
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDR1/P-gp and VEGF synergistically enhance the invasion of Hep-2 cells with multidrug resistance induced by taxol.
    Li L; Jiang AC; Dong P; Wang H; Xu W; Xu C
    Ann Surg Oncol; 2009 May; 16(5):1421-8. PubMed ID: 19247716
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative polymerase chain reaction analysis of mdr1 mRNA in multiple myeloma cell lines and clinical specimens.
    Futscher BW; Blake LL; Gerlach JH; Grogan TM; Dalton WS
    Anal Biochem; 1993 Sep; 213(2):414-21. PubMed ID: 8238918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The reversion effect of the RNAi-silencing mdr1 gene on multidrug resistance of the leukemia cell HT9.
    Shao SL; Sun YY; Li XY; Zhang WW; Fu B; Yun DZ; Zuo MX
    Cell Biol Int; 2008 Aug; 32(8):893-8. PubMed ID: 18499486
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development and characterization of a melphalan-resistant human multiple myeloma cell line.
    Bellamy WT; Dalton WS; Gleason MC; Grogan TM; Trent JM
    Cancer Res; 1991 Feb; 51(3):995-1002. PubMed ID: 1988143
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Down-regulation of CD98 in melphalan-resistant myeloma cells with reduced drug uptake.
    Harada N; Nagasaki A; Hata H; Matsuzaki H; Matsuno F; Mitsuya H
    Acta Haematol; 2000; 103(3):144-51. PubMed ID: 10940652
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.