135 related articles for article (PubMed ID: 19448839)
1. Syntheses and Structure-Activity Relationships of Novel 3'-Difluoromethyl and 3'-Trifluoromethyl-Taxoids.
Kuznetsova LV; Pepe A; Ungureanu IM; Pera P; Bernacki RJ; Ojima I
J Fluor Chem; 2008; 129(9):817-828. PubMed ID: 19448839
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and SAR study of 3rd-generation taxoids bearing 3-CH
Wang C; Wang X; Sun Y; Taouil AK; Yan S; Botchkina GI; Ojima I
Bioorg Chem; 2020 Jan; 95():103523. PubMed ID: 31911305
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids.
Kuznetsova L; Sun L; Chen J; Zhao X; Seitz J; Das M; Li Y; Veith JM; Pera P; Bernacki RJ; Xia S; Horwitz SB; Ojima I
J Fluor Chem; 2012 Nov; 143():177-188. PubMed ID: 23139432
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and SAR study of Fluorine-containing 3rd-generation taxoids.
Wang C; Chen L; Sun Y; Guo W; Taouil AK; Ojima I
Bioorg Chem; 2022 Feb; 119():105578. PubMed ID: 34979464
[TBL] [Abstract][Full Text] [Related]
5. Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells.
Ojima I; Slater JC; Michaud E; Kuduk SD; Bounaud PY; Vrignaud P; Bissery MC; Veith JM; Pera P; Bernacki RJ
J Med Chem; 1996 Sep; 39(20):3889-96. PubMed ID: 8831755
[TBL] [Abstract][Full Text] [Related]
6. Syntheses and biological activity of C-3'-difluoromethyl-taxoids.
Ojima I; Lin S; Slater JC; Wang T; Pera P; Bernacki RJ; Ferlini C; Scambia G
Bioorg Med Chem; 2000 Jul; 8(7):1619-28. PubMed ID: 10976509
[TBL] [Abstract][Full Text] [Related]
7. Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.
Ojima I; Slater JC; Kuduk SD; Takeuchi CS; Gimi RH; Sun CM; Park YH; Pera P; Veith JM; Bernacki RJ
J Med Chem; 1997 Jan; 40(3):267-78. PubMed ID: 9022793
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and biological evaluation of new-generation taxoids.
Ojima I; Chen J; Sun L; Borella CP; Wang T; Miller ML; Lin S; Geng X; Kuznetsova L; Qu C; Gallager D; Zhao X; Zanardi I; Xia S; Horwitz SB; Mallen-St Clair J; Guerriero JL; Bar-Sagi D; Veith JM; Pera P; Bernacki RJ
J Med Chem; 2008 Jun; 51(11):3203-21. PubMed ID: 18465846
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and structure-activity relationships of new second-generation taxoids.
Ojima I; Wang T; Miller ML; Lin S; Borella CP; Geng X; Pera P; Bernacki RJ
Bioorg Med Chem Lett; 1999 Dec; 9(24):3423-8. PubMed ID: 10617084
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and biological activity of novel C2-C3' N-Linked macrocyclic taxoids.
Ojima I; Geng X; Lin S; Pera P; Bernacki RJ
Bioorg Med Chem Lett; 2002 Feb; 12(3):349-52. PubMed ID: 11814794
[TBL] [Abstract][Full Text] [Related]
11. Investigation of 3'-debenzoyl-3'-(3-([¹²⁴I]-iodobenzoyl))paclitaxel analog as a radio-tracer to study multidrug resistance in vivo.
Sajjad M; Riaz U; Yao R; Bernacki RJ; Abouzied M; Erb DA; Chaudhary ND; Veith JM; Georg GI; Nabi HA
Appl Radiat Isot; 2012 Aug; 70(8):1624-31. PubMed ID: 22738838
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of new antitumor taxoids. Effects of cyclohexyl substitution at the C-3' and/or C-2 of taxotere (docetaxel).
Ojima I; Duclos O; Zucco M; Bissery MC; Combeau C; Vrignaud P; Riou JF; Lavelle F
J Med Chem; 1994 Aug; 37(16):2602-8. PubMed ID: 7914541
[TBL] [Abstract][Full Text] [Related]
13. Recent advances in the chemistry and biology of new generation taxoids.
Ojima I; Das M
J Nat Prod; 2009 Mar; 72(3):554-65. PubMed ID: 19239240
[TBL] [Abstract][Full Text] [Related]
14. The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin.
Xiong XB; Ma Z; Lai R; Lavasanifar A
Biomaterials; 2010 Feb; 31(4):757-68. PubMed ID: 19818492
[TBL] [Abstract][Full Text] [Related]
15. Chemistry and chemical biology of taxane anticancer agents.
Miller ML; Ojima I
Chem Rec; 2001; 1(3):195-211. PubMed ID: 11895119
[TBL] [Abstract][Full Text] [Related]
16. Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.
Tang Y; Rodríguez-Salarichs J; Zhao Y; Cai P; Estévez-Gallego J; Balaguer-Pérez F; Redondo Horcajo M; Lucena-Agell D; Barasoain I; Díaz JF; Fang WS
Eur J Med Chem; 2017 Sep; 137():488-503. PubMed ID: 28624703
[TBL] [Abstract][Full Text] [Related]
17. General and recent aspects of the chemistry and structure-activity relationships of taxoids.
Guéritte F
Curr Pharm Des; 2001 Sep; 7(13):1229-49. PubMed ID: 11472264
[TBL] [Abstract][Full Text] [Related]
18. Differential cytotoxic effects of docetaxel in a range of mammalian tumor cell lines and certain drug resistant sublines in vitro.
Hill BT; Whelan RD; Shellard SA; McClean S; Hosking LK
Invest New Drugs; 1994; 12(3):169-82. PubMed ID: 7896535
[TBL] [Abstract][Full Text] [Related]
19. Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents.
Kuznetsova L; Chen J; Sun L; Wu X; Pepe A; Veith JM; Pera P; Bernacki RJ; Ojima I
Bioorg Med Chem Lett; 2006 Feb; 16(4):974-7. PubMed ID: 16298526
[TBL] [Abstract][Full Text] [Related]
20. Recent progress in the strategic incorporation of fluorine into medicinally active compounds.
Haranahalli K; Honda T; Ojima I
J Fluor Chem; 2019 Jan; 217():29-40. PubMed ID: 31537946
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]