177 related articles for article (PubMed ID: 19450723)
1. Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6.
Gao MH; Miyanohara A; Feramisco JR; Tang T
Biochem Biophys Res Commun; 2009 Jun; 384(2):193-8. PubMed ID: 19450723
[TBL] [Abstract][Full Text] [Related]
2. beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling.
Gao MH; Tang T; Miyanohara A; Feramisco JR; Hammond HK
Cell Signal; 2010 Apr; 22(4):584-9. PubMed ID: 19932173
[TBL] [Abstract][Full Text] [Related]
3. Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant.
Gao MH; Tang T; Lai NC; Miyanohara A; Guo T; Tang R; Firth AL; Yuan JX; Hammond HK
Mol Pharmacol; 2011 Mar; 79(3):381-8. PubMed ID: 21127130
[TBL] [Abstract][Full Text] [Related]
4. PHLiPPing the switch on Akt and protein kinase C signaling.
Brognard J; Newton AC
Trends Endocrinol Metab; 2008 Aug; 19(6):223-30. PubMed ID: 18511290
[TBL] [Abstract][Full Text] [Related]
5. PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.
Brognard J; Sierecki E; Gao T; Newton AC
Mol Cell; 2007 Mar; 25(6):917-31. PubMed ID: 17386267
[TBL] [Abstract][Full Text] [Related]
6. Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling.
Huang J; Cai C; Zheng T; Wu X; Wang D; Zhang K; Xu B; Yan R; Gong H; Zhang J; Shi Y; Xu Z; Zhang X; Zhang X; Shang T; Zhou J; Guo X; Zeng C; Lai EY; Xiao C; Chen J; Wan S; Liu WH; Ke Y; Cheng H
Arterioscler Thromb Vasc Biol; 2020 Jul; 40(7):1705-1721. PubMed ID: 32268790
[TBL] [Abstract][Full Text] [Related]
7. Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes.
Gao MH; Tang T; Guo T; Miyanohara A; Yajima T; Pestonjamasp K; Feramisco JR; Hammond HK
J Biol Chem; 2008 Nov; 283(48):33527-35. PubMed ID: 18838385
[TBL] [Abstract][Full Text] [Related]
8. PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) regulates G-protein-coupled receptor kinase 5 (GRK5)-induced cardiac hypertrophy
Yeh ST; Zambrano CM; Koch WJ; Purcell NH
J Biol Chem; 2018 May; 293(21):8056-8064. PubMed ID: 29628444
[TBL] [Abstract][Full Text] [Related]
9. Diacylglycerol kinase δ modulates Akt phosphorylation through pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2).
Crotty TM; Nakano T; Stafforini DM; Topham MK
J Biol Chem; 2013 Jan; 288(3):1439-47. PubMed ID: 23184957
[TBL] [Abstract][Full Text] [Related]
10. The phosphatase PHLPP controls the cellular levels of protein kinase C.
Gao T; Brognard J; Newton AC
J Biol Chem; 2008 Mar; 283(10):6300-11. PubMed ID: 18162466
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes.
Jackson TC; Verrier JD; Drabek T; Janesko-Feldman K; Gillespie DG; Uray T; Dezfulian C; Clark RS; Bayir H; Jackson EK; Kochanek PM
J Pharmacol Exp Ther; 2013 Nov; 347(2):516-28. PubMed ID: 24023368
[TBL] [Abstract][Full Text] [Related]
12. Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death.
Saxena S; Shukla S; Kakkar P
Toxicol Appl Pharmacol; 2018 May; 347():92-103. PubMed ID: 29626488
[TBL] [Abstract][Full Text] [Related]
13. Assembly of the FKBP51-PHLPP2-AKT signaling complex in cerebral ischemia/reperfusion injury in rats.
Wei XE; Zhang FY; Wang K; Zhang QX; Rong LQ
Brain Res; 2014 May; 1566():60-8. PubMed ID: 24746496
[TBL] [Abstract][Full Text] [Related]
14. Activity of Adenylyl Cyclase Type 6 Is Suppressed by Direct Binding of the Cytoskeletal Protein 4.1G.
Saito M; Cui L; Hirano M; Li G; Yanagisawa T; Sato T; Sukegawa J
Mol Pharmacol; 2019 Oct; 96(4):441-451. PubMed ID: 31383768
[TBL] [Abstract][Full Text] [Related]
15. The type VI adenylyl cyclase protects cardiomyocytes from β-adrenergic stress by a PKA/STAT3-dependent pathway.
Wu YS; Chen CC; Chien CL; Lai HL; Jiang ST; Chen YC; Lai LP; Hsiao WF; Chen WP; Chern Y
J Biomed Sci; 2017 Sep; 24(1):68. PubMed ID: 28870220
[TBL] [Abstract][Full Text] [Related]
16. Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.
Hirano I; Nakamura S; Yokota D; Ono T; Shigeno K; Fujisawa S; Shinjo K; Ohnishi K
J Biol Chem; 2009 Aug; 284(33):22155-22165. PubMed ID: 19261608
[TBL] [Abstract][Full Text] [Related]
17. Regulation of adenylyl cyclase type VI activity during desensitization of the A2a adenosine receptor-mediated cyclic AMP response: role for protein phosphatase 2A.
Chern Y; Chiou JY; Lai HL; Tsai MH
Mol Pharmacol; 1995 Jul; 48(1):1-8. PubMed ID: 7623763
[TBL] [Abstract][Full Text] [Related]
18. Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C.
Brognard J; Niederst M; Reyes G; Warfel N; Newton AC
J Biol Chem; 2009 May; 284(22):15215-23. PubMed ID: 19324870
[TBL] [Abstract][Full Text] [Related]
19. The lack of homology domain and leucine rich repeat protein phosphatase 2 ameliorates visual impairment in rats with diabetic retinopathy through regulation of the AKT-GSK-3β-Nrf2 signal cascade.
Chen L; Qi E; Liu X; Cui L; Fan X; Wei T; Hu Y
Toxicol Appl Pharmacol; 2024 Jan; 482():116766. PubMed ID: 37995808
[TBL] [Abstract][Full Text] [Related]
20. PHLPP-1 negatively regulates Akt activity and survival in the heart.
Miyamoto S; Purcell NH; Smith JM; Gao T; Whittaker R; Huang K; Castillo R; Glembotski CC; Sussman MA; Newton AC; Brown JH
Circ Res; 2010 Aug; 107(4):476-84. PubMed ID: 20576936
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
