404 related articles for article (PubMed ID: 19450980)
1. Discovery and structure-guided drug design of inhibitors of 11beta-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold.
Lepifre F; Christmann-Franck S; Roche D; Leriche C; Carniato D; Charon C; Bozec S; Doare L; Schmidlin F; Lecomte M; Valeur E
Bioorg Med Chem Lett; 2009 Jul; 19(13):3682-5. PubMed ID: 19450980
[TBL] [Abstract][Full Text] [Related]
2. Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Roche D; Carniato D; Leriche C; Lepifre F; Christmann-Franck S; Graedler U; Charon C; Bozec S; Doare L; Schmidlin F; Lecomte M; Valeur E
Bioorg Med Chem Lett; 2009 May; 19(10):2674-8. PubMed ID: 19395260
[TBL] [Abstract][Full Text] [Related]
3. Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11β-hydroxysteroid dehydrogenase type I.
Valeur E; Christmann-Franck S; Lepifre F; Carniato D; Cravo D; Charon C; Bozec S; Musil D; Hillertz P; Doare L; Schmidlin F; Lecomte M; Schultz M; Roche D
Bioorg Med Chem Lett; 2012 Sep; 22(18):5909-14. PubMed ID: 22901389
[TBL] [Abstract][Full Text] [Related]
4. Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1).
Sun D; Wang Z; Di Y; Jaen JC; Labelle M; Ma J; Miao S; Sudom A; Tang L; Tomooka CS; Tu H; Ursu S; Walker N; Yan X; Ye Q; Powers JP
Bioorg Med Chem Lett; 2008 Jun; 18(12):3513-6. PubMed ID: 18511278
[TBL] [Abstract][Full Text] [Related]
5. The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors.
Cheng H; Hoffman J; Le P; Nair SK; Cripps S; Matthews J; Smith C; Yang M; Kupchinsky S; Dress K; Edwards M; Cole B; Walters E; Loh C; Ermolieff J; Fanjul A; Bhat GB; Herrera J; Pauly T; Hosea N; Paderes G; Rejto P
Bioorg Med Chem Lett; 2010 May; 20(9):2897-902. PubMed ID: 20363126
[TBL] [Abstract][Full Text] [Related]
6. Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
Webster SP; Ward P; Binnie M; Craigie E; McConnell KM; Sooy K; Vinter A; Seckl JR; Walker BR
Bioorg Med Chem Lett; 2007 May; 17(10):2838-43. PubMed ID: 17350260
[TBL] [Abstract][Full Text] [Related]
7. Piperidine amides as 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
Flyrén K; Bergquist LO; Castro VM; Fotsch C; Johansson L; St Jean DJ; Sutin L; Williams M
Bioorg Med Chem Lett; 2007 Jun; 17(12):3421-5. PubMed ID: 17442567
[TBL] [Abstract][Full Text] [Related]
8. Discovery of novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling.
Yang H; Dou W; Lou J; Leng Y; Shen J
Bioorg Med Chem Lett; 2008 Feb; 18(4):1340-5. PubMed ID: 18242087
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
Stanetty C; Czollner L; Koller I; Shah P; Gaware R; Cunha TD; Odermatt A; Jordis U; Kosma P; Classen-Houben D
Bioorg Med Chem; 2010 Nov; 18(21):7522-41. PubMed ID: 20851614
[TBL] [Abstract][Full Text] [Related]
10. 3-Amino-N-adamantyl-3-methylbutanamide derivatives as 11β-hydroxysteroid dehydrogenase 1 inhibitor.
Lee Y; Shin YJ; Ahn SK
Bioorg Med Chem Lett; 2014 Mar; 24(5):1421-5. PubMed ID: 24507919
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of sulfonamidooxazoles and beta-keto sulfones: selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
Xiang J; Ipek M; Suri V; Massefski W; Pan N; Ge Y; Tam M; Xing Y; Tobin JF; Xu X; Tam S
Bioorg Med Chem Lett; 2005 Jun; 15(11):2865-9. PubMed ID: 15911270
[TBL] [Abstract][Full Text] [Related]
12. Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors.
Su X; Pradaux-Caggiano F; Thomas MP; Szeto MW; Halem HA; Culler MD; Vicker N; Potter BV
ChemMedChem; 2010 Jul; 5(7):1026-44. PubMed ID: 20486152
[TBL] [Abstract][Full Text] [Related]
13. Structure-based virtual screening for identification of novel 11beta-HSD1 inhibitors.
Yang H; Shen Y; Chen J; Jiang Q; Leng Y; Shen J
Eur J Med Chem; 2009 Mar; 44(3):1167-71. PubMed ID: 18653260
[TBL] [Abstract][Full Text] [Related]
14. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
Su X; Vicker N; Trusselle M; Halem H; Culler MD; Potter BV
Mol Cell Endocrinol; 2009 Mar; 301(1-2):169-73. PubMed ID: 18775471
[TBL] [Abstract][Full Text] [Related]
15. The discovery of azepane sulfonamides as potent 11beta-HSD1 inhibitors.
Neelamkavil SF; Boyle CD; Chackalamannil S; Greenlee WJ; Zhang L; Terracina G
Bioorg Med Chem Lett; 2009 Aug; 19(16):4563-5. PubMed ID: 19625185
[TBL] [Abstract][Full Text] [Related]
16. Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Wang H; Ruan Z; Li JJ; Simpkins LM; Smirk RA; Wu SC; Hutchins RD; Nirschl DS; Van Kirk K; Cooper CB; Sutton JC; Ma Z; Golla R; Seethala R; Salyan ME; Nayeem A; Krystek SR; Sheriff S; Camac DM; Morin PE; Carpenter B; Robl JA; Zahler R; Gordon DA; Hamann LG
Bioorg Med Chem Lett; 2008 Jun; 18(11):3168-72. PubMed ID: 18485702
[TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of (R)-1-arylsulfonylpiperidine-2-carboxamides as 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
Xia G; Liu L; Liu H; Yu J; Xu Z; Chen Q; Ma C; Li P; Xiong B; Liu X; Shen J
ChemMedChem; 2013 Apr; 8(4):577-81. PubMed ID: 23471829
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors.
Gaware R; Khunt R; Czollner L; Stanetty C; Da Cunha T; Kratschmar DV; Odermatt A; Kosma P; Jordis U; Classen-Houben D
Bioorg Med Chem; 2011 Mar; 19(6):1866-80. PubMed ID: 21376605
[TBL] [Abstract][Full Text] [Related]
19. Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.
Hult M; Shafqat N; Elleby B; Mitschke D; Svensson S; Forsgren M; Barf T; Vallgårda J; Abrahmsen L; Oppermann U
Mol Cell Endocrinol; 2006 Mar; 248(1-2):26-33. PubMed ID: 16431016
[TBL] [Abstract][Full Text] [Related]
20. Oxazolones as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Sutin L; Andersson S; Bergquist L; Castro VM; Danielsson E; James S; Henriksson M; Johansson L; Kaiser C; Flyrén K; Williams M
Bioorg Med Chem Lett; 2007 Sep; 17(17):4837-40. PubMed ID: 17600707
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]