BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

280 related articles for article (PubMed ID: 19451263)

  • 1. Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis.
    Shao L; Fujii H; Colmegna I; Oishi H; Goronzy JJ; Weyand CM
    J Exp Med; 2009 Jun; 206(6):1435-49. PubMed ID: 19451263
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
    Morales M; Theunissen JW; Kim CF; Kitagawa R; Kastan MB; Petrini JH
    Genes Dev; 2005 Dec; 19(24):3043-54. PubMed ID: 16357220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
    Stracker TH; Morales M; Couto SS; Hussein H; Petrini JH
    Nature; 2007 May; 447(7141):218-21. PubMed ID: 17429352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rejuvenating the immune system in rheumatoid arthritis.
    Weyand CM; Fujii H; Shao L; Goronzy JJ
    Nat Rev Rheumatol; 2009 Oct; 5(10):583-8. PubMed ID: 19798035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.
    Shull ER; Lee Y; Nakane H; Stracker TH; Zhao J; Russell HR; Petrini JH; McKinnon PJ
    Genes Dev; 2009 Jan; 23(2):171-80. PubMed ID: 19171781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purification and biochemical characterization of ataxia-telangiectasia mutated and Mre11/Rad50/Nbs1.
    Lee JH; Paull TT
    Methods Enzymol; 2006; 408():529-39. PubMed ID: 16793391
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
    Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
    J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Ewald B; Sampath D; Plunkett W
    Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.
    Lee JH; Paull TT
    Oncogene; 2007 Dec; 26(56):7741-8. PubMed ID: 18066086
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
    Taylor AM; Groom A; Byrd PJ
    DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
    Lee JH; Paull TT
    Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Mre11 complex and ATM: a two-way functional interaction in recognising and signaling DNA double strand breaks.
    Lavin MF
    DNA Repair (Amst); 2004 Nov; 3(11):1515-20. PubMed ID: 15380107
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.
    Lavin MF
    Oncogene; 2007 Dec; 26(56):7749-58. PubMed ID: 18066087
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.
    Difilippantonio S; Celeste A; Fernandez-Capetillo O; Chen HT; Reina San Martin B; Van Laethem F; Yang YP; Petukhova GV; Eckhaus M; Feigenbaum L; Manova K; Kruhlak M; Camerini-Otero RD; Sharan S; Nussenzweig M; Nussenzweig A
    Nat Cell Biol; 2005 Jul; 7(7):675-85. PubMed ID: 15965469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.
    Gladdy RA; Nutter LM; Kunath T; Danska JS; Guidos CJ
    Mol Cancer Res; 2006 May; 4(5):311-8. PubMed ID: 16687486
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex.
    Lee JH; Paull TT
    Science; 2004 Apr; 304(5667):93-6. PubMed ID: 15064416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin.
    Folk WP; Kumari A; Iwasaki T; Pyndiah S; Johnson JC; Cassimere EK; Abdulovic-Cui AL; Sakamuro D
    J Biol Chem; 2019 Apr; 294(14):5700-5719. PubMed ID: 30733337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection.
    Shirata N; Kudoh A; Daikoku T; Tatsumi Y; Fujita M; Kiyono T; Sugaya Y; Isomura H; Ishizaki K; Tsurumi T
    J Biol Chem; 2005 Aug; 280(34):30336-41. PubMed ID: 15964848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype.
    Gueven N; Becherel OJ; Birrell G; Chen P; DelSal G; Carney JP; Grattan-Smith P; Lavin MF
    Cancer Res; 2006 Mar; 66(6):2907-12. PubMed ID: 16540636
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
    Darlington Y; Nguyen TA; Moon SH; Herron A; Rao P; Zhu C; Lu X; Donehower LA
    Oncogene; 2012 Mar; 31(9):1155-65. PubMed ID: 21765465
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.