BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 19454487)

  • 1. Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis.
    Shi Y; Ghosh MC; Tong WH; Rouault TA
    Hum Mol Genet; 2009 Aug; 18(16):3014-25. PubMed ID: 19454487
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1.
    Friemel M; Marelja Z; Li K; Leimkühler S
    Biochemistry; 2017 Mar; 56(12):1797-1808. PubMed ID: 28271877
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions.
    Cory SA; Van Vranken JG; Brignole EJ; Patra S; Winge DR; Drennan CL; Rutter J; Barondeau DP
    Proc Natl Acad Sci U S A; 2017 Jul; 114(27):E5325-E5334. PubMed ID: 28634302
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes.
    Lim SC; Friemel M; Marum JE; Tucker EJ; Bruno DL; Riley LG; Christodoulou J; Kirk EP; Boneh A; DeGennaro CM; Springer M; Mootha VK; Rouault TA; Leimkühler S; Thorburn DR; Compton AG
    Hum Mol Genet; 2013 Nov; 22(22):4460-73. PubMed ID: 23814038
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mapping Key Residues of ISD11 Critical for NFS1-ISD11 Subcomplex Stability: IMPLICATIONS IN THE DEVELOPMENT OF MITOCHONDRIAL DISORDER, COXPD19.
    Saha PP; Srivastava S; Kumar S K P; Sinha D; D'Silva P
    J Biol Chem; 2015 Oct; 290(43):25876-90. PubMed ID: 26342079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis.
    Cai K; Tonelli M; Frederick RO; Markley JL
    Biochemistry; 2017 Jan; 56(3):487-499. PubMed ID: 28001042
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins.
    Wiedemann N; Urzica E; Guiard B; Müller H; Lohaus C; Meyer HE; Ryan MT; Meisinger C; Mühlenhoff U; Lill R; Pfanner N
    EMBO J; 2006 Jan; 25(1):184-95. PubMed ID: 16341089
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria.
    Adam AC; Bornhövd C; Prokisch H; Neupert W; Hell K
    EMBO J; 2006 Jan; 25(1):174-83. PubMed ID: 16341090
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
    Boniecki MT; Freibert SA; Mühlenhoff U; Lill R; Cygler M
    Nat Commun; 2017 Nov; 8(1):1287. PubMed ID: 29097656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis.
    Tong WH; Rouault TA
    Cell Metab; 2006 Mar; 3(3):199-210. PubMed ID: 16517407
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly.
    Pandey A; Gordon DM; Pain J; Stemmler TL; Dancis A; Pain D
    J Biol Chem; 2013 Dec; 288(52):36773-86. PubMed ID: 24217246
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation.
    Biederbick A; Stehling O; Rösser R; Niggemeyer B; Nakai Y; Elsässer HP; Lill R
    Mol Cell Biol; 2006 Aug; 26(15):5675-87. PubMed ID: 16847322
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mammalian iron-sulfur cluster biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins.
    Maio N; Jain A; Rouault TA
    Curr Opin Chem Biol; 2020 Apr; 55():34-44. PubMed ID: 31918395
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial Cysteine Desulfurase and ISD11 Coexpressed in Escherichia coli Yield Complex Containing Acyl Carrier Protein.
    Cai K; Frederick RO; Tonelli M; Markley JL
    ACS Chem Biol; 2017 Apr; 12(4):918-921. PubMed ID: 28233492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS.
    Yan R; Friemel M; Aloisi C; Huynen M; Taylor IA; Leimkühler S; Pastore A
    PLoS One; 2016; 11(7):e0157895. PubMed ID: 27427956
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery.
    Gakh O; Ranatunga W; Smith DY; Ahlgren EC; Al-Karadaghi S; Thompson JR; Isaya G
    J Biol Chem; 2016 Sep; 291(40):21296-21321. PubMed ID: 27519411
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).
    Cai K; Frederick RO; Kim JH; Reinen NM; Tonelli M; Markley JL
    J Biol Chem; 2013 Oct; 288(40):28755-70. PubMed ID: 23940031
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Human Iron-Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules.
    Fox NG; Chakrabarti M; McCormick SP; Lindahl PA; Barondeau DP
    Biochemistry; 2015 Jun; 54(25):3871-9. PubMed ID: 26016389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rescuing the Rescuer: On the Protein Complex between the Human Mitochondrial Acyl Carrier Protein and ISD11.
    Herrera MG; Pignataro MF; Noguera ME; Cruz KM; Santos J
    ACS Chem Biol; 2018 Jun; 13(6):1455-1462. PubMed ID: 29737835
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria.
    Gakh O; Ranatunga W; Galeano BK; Smith DS; Thompson JR; Isaya G
    Methods Enzymol; 2017; 595():107-160. PubMed ID: 28882199
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.