BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

564 related articles for article (PubMed ID: 19455606)

  • 1. Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
    Niessen RC; Hofstra RM; Westers H; Ligtenberg MJ; Kooi K; Jager PO; de Groote ML; Dijkhuizen T; Olderode-Berends MJ; Hollema H; Kleibeuker JH; Sijmons RH
    Genes Chromosomes Cancer; 2009 Aug; 48(8):737-44. PubMed ID: 19455606
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frequency of rearrangements in Lynch syndrome cases associated with MSH2: characterization of a new deletion involving both EPCAM and the 5' part of MSH2.
    Pérez-Cabornero L; Infante Sanz M; Velasco Sampedro E; Lastra Aras E; Acedo Becares A; Miner Pino C; Durán Domínguez M
    Cancer Prev Res (Phila); 2011 Oct; 4(10):1556-62. PubMed ID: 21791569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. EPCAM germline and somatic rearrangements in Lynch syndrome: identification of a novel 3'EPCAM deletion.
    Spaepen M; Neven E; Sagaert X; De Hertogh G; Beert E; Wimmer K; Matthijs G; Legius E; Brems H
    Genes Chromosomes Cancer; 2013 Sep; 52(9):845-54. PubMed ID: 23801599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases.
    Rumilla K; Schowalter KV; Lindor NM; Thomas BC; Mensink KA; Gallinger S; Holter S; Newcomb PA; Potter JD; Jenkins MA; Hopper JL; Long TI; Weisenberger DJ; Haile RW; Casey G; Laird PW; Le Marchand L; Thibodeau SN
    J Mol Diagn; 2011 Jan; 13(1):93-9. PubMed ID: 21227399
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coexisting somatic promoter hypermethylation and pathogenic MLH1 germline mutation in Lynch syndrome.
    Rahner N; Friedrichs N; Steinke V; Aretz S; Friedl W; Buettner R; Mangold E; Propping P; Walldorf C
    J Pathol; 2008 Jan; 214(1):10-6. PubMed ID: 17973250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EPCAM germ line deletions as causes of Lynch syndrome in Spanish patients.
    Guarinos C; Castillejo A; Barberá VM; Pérez-Carbonell L; Sánchez-Heras AB; Segura A; Guillén-Ponce C; Martínez-Cantó A; Castillejo MI; Egoavil CM; Jover R; Payá A; Alenda C; Soto JL
    J Mol Diagn; 2010 Nov; 12(6):765-70. PubMed ID: 20864635
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Screening for germline mutations of MLH1, MSH2, MSH6 and PMS2 genes in Slovenian colorectal cancer patients: implications for a population specific detection strategy of Lynch syndrome.
    Berginc G; Bracko M; Ravnik-Glavac M; Glavac D
    Fam Cancer; 2009; 8(4):421-9. PubMed ID: 19526325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. "Null pattern" of immunoreactivity in a Lynch syndrome-associated colon cancer due to germline MSH2 mutation and somatic MLH1 hypermethylation.
    Hagen CE; Lefferts J; Hornick JL; Srivastava A
    Am J Surg Pathol; 2011 Dec; 35(12):1902-5. PubMed ID: 22067334
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prospective determination of prevalence of lynch syndrome in young women with endometrial cancer.
    Lu KH; Schorge JO; Rodabaugh KJ; Daniels MS; Sun CC; Soliman PT; White KG; Luthra R; Gershenson DM; Broaddus RR
    J Clin Oncol; 2007 Nov; 25(33):5158-64. PubMed ID: 17925543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of EPCAM protein expression in diagnostics of Lynch syndrome.
    Kloor M; Voigt AY; Schackert HK; Schirmacher P; von Knebel Doeberitz M; Bläker H
    J Clin Oncol; 2011 Jan; 29(2):223-7. PubMed ID: 21115857
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutations.
    Haraldsdottir S; Hampel H; Tomsic J; Frankel WL; Pearlman R; de la Chapelle A; Pritchard CC
    Gastroenterology; 2014 Dec; 147(6):1308-1316.e1. PubMed ID: 25194673
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Universal screening for Lynch syndrome in endometrial cancers: frequency of germline mutations and identification of patients with Lynch-like syndrome.
    Dillon JL; Gonzalez JL; DeMars L; Bloch KJ; Tafe LJ
    Hum Pathol; 2017 Dec; 70():121-128. PubMed ID: 29107668
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recurrence and variability of germline EPCAM deletions in Lynch syndrome.
    Kuiper RP; Vissers LE; Venkatachalam R; Bodmer D; Hoenselaar E; Goossens M; Haufe A; Kamping E; Niessen RC; Hogervorst FB; Gille JJ; Redeker B; Tops CM; van Gijn ME; van den Ouweland AM; Rahner N; Steinke V; Kahl P; Holinski-Feder E; Morak M; Kloor M; Stemmler S; Betz B; Hutter P; Bunyan DJ; Syngal S; Culver JO; Graham T; Chan TL; Nagtegaal ID; van Krieken JH; Schackert HK; Hoogerbrugge N; van Kessel AG; Ligtenberg MJ
    Hum Mutat; 2011 Apr; 32(4):407-14. PubMed ID: 21309036
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a Japanese Lynch syndrome patient with large deletion in the 3' region of the EPCAM gene.
    Eguchi H; Kumamoto K; Suzuki O; Kohda M; Tada Y; Okazaki Y; Ishida H
    Jpn J Clin Oncol; 2016 Feb; 46(2):178-84. PubMed ID: 26613680
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MLH1 promoter germline-methylation in selected probands of Chinese hereditary non-polyposis colorectal cancer families.
    Zhou HH; Yan SY; Zhou XY; Du X; Zhang TM; Cai X; Lu YM; Cai SJ; Shi DR
    World J Gastroenterol; 2008 Dec; 14(48):7329-34. PubMed ID: 19109866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Somatic mutations in MLH1 and MSH2 are a frequent cause of mismatch-repair deficiency in Lynch syndrome-like tumors.
    Mensenkamp AR; Vogelaar IP; van Zelst-Stams WA; Goossens M; Ouchene H; Hendriks-Cornelissen SJ; Kwint MP; Hoogerbrugge N; Nagtegaal ID; Ligtenberg MJ
    Gastroenterology; 2014 Mar; 146(3):643-646.e8. PubMed ID: 24333619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Redundant DNA methylation in colorectal cancers of Lynch-syndrome patients.
    Alemayehu A; Sebova K; Fridrichova I
    Genes Chromosomes Cancer; 2008 Oct; 47(10):906-14. PubMed ID: 18618713
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study.
    Kloor M; Huth C; Voigt AY; Benner A; Schirmacher P; von Knebel Doeberitz M; Bläker H
    Lancet Oncol; 2012 Jun; 13(6):598-606. PubMed ID: 22552011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spectrum of MLH1 and MSH2 mutations in Chilean families with suspected Lynch syndrome.
    Alvarez K; Hurtado C; Hevia MA; Wielandt AM; de la Fuente M; Church J; Carvallo P; López-Köstner F
    Dis Colon Rectum; 2010 Apr; 53(4):450-9. PubMed ID: 20305446
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers.
    Kang SY; Park CK; Chang DK; Kim JW; Son HJ; Cho YB; Yun SH; Kim HC; Kwon M; Kim KM
    Int J Cancer; 2015 Apr; 136(7):1568-78. PubMed ID: 25110875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.