BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 19461893)

  • 1. Accumulating progenitor cells in the luminal epithelial cell layer are candidate tumor initiating cells in a Pten knockout mouse prostate cancer model.
    Korsten H; Ziel-van der Made A; Ma X; van der Kwast T; Trapman J
    PLoS One; 2009 May; 4(5):e5662. PubMed ID: 19461893
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis.
    Ma X; Ziel-van der Made AC; Autar B; van der Korput HA; Vermeij M; van Duijn P; Cleutjens KB; de Krijger R; Krimpenfort P; Berns A; van der Kwast TH; Trapman J
    Cancer Res; 2005 Jul; 65(13):5730-9. PubMed ID: 15994948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice.
    Korsten H; Ziel-van der Made AC; van Weerden WM; van der Kwast T; Trapman J; Van Duijn PW
    PLoS One; 2016; 11(1):e0147500. PubMed ID: 26807730
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A rare castration-resistant progenitor cell population is highly enriched in Pten-null prostate tumours.
    Sackmann Sala L; Boutillon F; Menara G; De Goyon-Pélard A; Leprévost M; Codzamanian J; Lister N; Pencik J; Clark A; Cagnard N; Bole-Feysot C; Moriggl R; Risbridger GP; Taylor RA; Kenner L; Guidotti JE; Goffin V
    J Pathol; 2017 Sep; 243(1):51-64. PubMed ID: 28603917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.
    Kwak MK; Johnson DT; Zhu C; Lee SH; Ye DW; Luong R; Sun Z
    PLoS One; 2013; 8(1):e53476. PubMed ID: 23308230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conditionally ablated Pten in prostate basal cells promotes basal-to-luminal differentiation and causes invasive prostate cancer in mice.
    Lu TL; Huang YF; You LR; Chao NC; Su FY; Chang JL; Chen CM
    Am J Pathol; 2013 Mar; 182(3):975-91. PubMed ID: 23313138
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.
    Abou-Kheir WG; Hynes PG; Martin PL; Pierce R; Kelly K
    Stem Cells; 2010 Dec; 28(12):2129-40. PubMed ID: 20936707
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An inducible knockout mouse to model the cell-autonomous role of PTEN in initiating endometrial, prostate and thyroid neoplasias.
    Mirantes C; Eritja N; Dosil MA; Santacana M; Pallares J; Gatius S; Bergadà L; Maiques O; Matias-Guiu X; Dolcet X
    Dis Model Mech; 2013 May; 6(3):710-20. PubMed ID: 23471917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell differentiation lineage in the prostate.
    Wang Y; Hayward S; Cao M; Thayer K; Cunha G
    Differentiation; 2001 Oct; 68(4-5):270-9. PubMed ID: 11776479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Region-specific role for Pten in maintenance of epithelial phenotype and integrity.
    Flodby P; Liebler JM; Sunohara M; Castillo DR; McConnell AM; Krishnaveni MS; Banfalvi A; Li M; Stripp B; Zhou B; Crandall ED; Minoo P; Borok Z
    Am J Physiol Lung Cell Mol Physiol; 2017 Jan; 312(1):L131-L142. PubMed ID: 27864284
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips.
    Guo W; Li L; He J; Liu Z; Han M; Li F; Xia X; Zhang X; Zhu Y; Wei Y; Li Y; Aji R; Dai H; Wei H; Li C; Chen Y; Chen L; Gao D
    Nat Genet; 2020 Sep; 52(9):908-918. PubMed ID: 32807988
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TGFβ signaling limits lineage plasticity in prostate cancer.
    Hao Y; Bjerke GA; Pietrzak K; Melhuish TA; Han Y; Turner SD; Frierson HF; Wotton D
    PLoS Genet; 2018 May; 14(5):e1007409. PubMed ID: 29782499
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor heterogeneity, aggressiveness, and immune cell composition in a novel syngeneic PSA-targeted Pten knockout mouse prostate cancer (MuCaP) model.
    van Duijn PW; Marques RB; Ziel-van der Made ACJ; van Zoggel HJAA; Aghai A; Berrevoets C; Debets R; Jenster G; Trapman J; van Weerden WM
    Prostate; 2018 Sep; 78(13):1013-1023. PubMed ID: 30133757
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay.
    Park JW; Lee JK; Phillips JW; Huang P; Cheng D; Huang J; Witte ON
    Proc Natl Acad Sci U S A; 2016 Apr; 113(16):4482-7. PubMed ID: 27044116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Self-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity.
    Abou-Kheir W; Hynes PG; Martin P; Yin JJ; Liu YN; Seng V; Lake R; Spurrier J; Kelly K
    PLoS One; 2011; 6(10):e26112. PubMed ID: 22022528
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma.
    Ratnacaram CK; Teletin M; Jiang M; Meng X; Chambon P; Metzger D
    Proc Natl Acad Sci U S A; 2008 Feb; 105(7):2521-6. PubMed ID: 18268330
    [TBL] [Abstract][Full Text] [Related]  

  • 17.
    Parisotto M; Grelet E; El Bizri R; Dai Y; Terzic J; Eckert D; Gargowitsch L; Bornert JM; Metzger D
    J Exp Med; 2018 Jun; 215(6):1749-1763. PubMed ID: 29743291
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monoamine Oxidase Deficiency Causes Prostate Atrophy and Reduces Prostate Progenitor Cell Activity.
    Yin L; Li J; Liao CP; Jason Wu B
    Stem Cells; 2018 Aug; 36(8):1249-1258. PubMed ID: 29637670
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteomic and transcriptomic profiling of Pten gene-knockout mouse model of prostate cancer.
    Zhang J; Kim S; Li L; Kemp CJ; Jiang C; Lü J
    Prostate; 2020 May; 80(7):588-605. PubMed ID: 32162714
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mouse prostate epithelial luminal cells lineage originate in the basal layer where the primitive stem/early progenitor cells reside: implications for identifying prostate cancer stem cells.
    Zhou J; Feigenbaum L; Yee C; Song H; Yates C
    Biomed Res Int; 2013; 2013():913179. PubMed ID: 23819124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.