242 related articles for article (PubMed ID: 19468851)
1. BioCores: identification of a drug/natural product-based privileged structural motif for small-molecule lead discovery.
Kombarov R; Altieri A; Genis D; Kirpichenok M; Kochubey V; Rakitina N; Titarenko Z
Mol Divers; 2010 Feb; 14(1):193-200. PubMed ID: 19468851
[TBL] [Abstract][Full Text] [Related]
2. Scaffold architecture and pharmacophoric properties of natural products and trade drugs: application in the design of natural product-based combinatorial libraries.
Lee ML; Schneider G
J Comb Chem; 2001; 3(3):284-9. PubMed ID: 11350252
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the Chemical Space of Known and Readily Obtainable Natural Products.
Chen Y; Garcia de Lomana M; Friedrich NO; Kirchmair J
J Chem Inf Model; 2018 Aug; 58(8):1518-1532. PubMed ID: 30010333
[TBL] [Abstract][Full Text] [Related]
4. Pseudo-natural products and natural product-inspired methods in chemical biology and drug discovery.
Grigalunas M; Burhop A; Christoforow A; Waldmann H
Curr Opin Chem Biol; 2020 Jun; 56():111-118. PubMed ID: 32362382
[TBL] [Abstract][Full Text] [Related]
5. Natural product derived privileged scaffolds in drug discovery.
Davison EK; Brimble MA
Curr Opin Chem Biol; 2019 Oct; 52():1-8. PubMed ID: 30682725
[TBL] [Abstract][Full Text] [Related]
6. Novel chemical space exploration via natural products.
Rosén J; Gottfries J; Muresan S; Backlund A; Oprea TI
J Med Chem; 2009 Apr; 52(7):1953-62. PubMed ID: 19265440
[TBL] [Abstract][Full Text] [Related]
7. Privileged scaffolds for library design and drug discovery.
Welsch ME; Snyder SA; Stockwell BR
Curr Opin Chem Biol; 2010 Jun; 14(3):347-61. PubMed ID: 20303320
[TBL] [Abstract][Full Text] [Related]
8. Design of Novel Drug-like Molecules Using Informatics Rich Secondary Metabolites Analysis of Indian Medicinal and Aromatic Plants.
Karade D; Vijayasarathi D; Kadoo N; Vyas R; Ingle PK; Karthikeyan M
Comb Chem High Throughput Screen; 2020; 23(10):1113-1131. PubMed ID: 32504496
[TBL] [Abstract][Full Text] [Related]
9. Chemoinformatic analysis of combinatorial libraries, drugs, natural products, and molecular libraries small molecule repository.
Singh N; Guha R; Giulianotti MA; Pinilla C; Houghten RA; Medina-Franco JL
J Chem Inf Model; 2009 Apr; 49(4):1010-24. PubMed ID: 19301827
[TBL] [Abstract][Full Text] [Related]
10. Classification of scaffold-hopping approaches.
Sun H; Tawa G; Wallqvist A
Drug Discov Today; 2012 Apr; 17(7-8):310-24. PubMed ID: 22056715
[TBL] [Abstract][Full Text] [Related]
11. Quest for the rings. In silico exploration of ring universe to identify novel bioactive heteroaromatic scaffolds.
Ertl P; Jelfs S; Mühlbacher J; Schuffenhauer A; Selzer P
J Med Chem; 2006 Jul; 49(15):4568-73. PubMed ID: 16854061
[TBL] [Abstract][Full Text] [Related]
12. Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.
Wenderski TA; Stratton CF; Bauer RA; Kopp F; Tan DS
Methods Mol Biol; 2015; 1263():225-42. PubMed ID: 25618349
[TBL] [Abstract][Full Text] [Related]
13. Expanding the medicinally relevant chemical space with compound libraries.
López-Vallejo F; Giulianotti MA; Houghten RA; Medina-Franco JL
Drug Discov Today; 2012 Jul; 17(13-14):718-26. PubMed ID: 22515962
[TBL] [Abstract][Full Text] [Related]
14. Identification and selection of "privileged fragments" suitable for primary screening.
Gianti E; Sartori L
J Chem Inf Model; 2008 Nov; 48(11):2129-39. PubMed ID: 18991373
[TBL] [Abstract][Full Text] [Related]
15. Scopy: an integrated negative design python library for desirable HTS/VS database design.
Yang ZY; Yang ZJ; Lu AP; Hou TJ; Cao DS
Brief Bioinform; 2021 May; 22(3):. PubMed ID: 32892221
[TBL] [Abstract][Full Text] [Related]
16. Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products.
Annamalai M; Hristeva S; Bielska M; Ortega R; Kumar K
Molecules; 2017 May; 22(5):. PubMed ID: 28524077
[TBL] [Abstract][Full Text] [Related]
17. Natural products as leads to potential drugs: an old process or the new hope for drug discovery?
Newman DJ
J Med Chem; 2008 May; 51(9):2589-99. PubMed ID: 18393402
[No Abstract] [Full Text] [Related]
18. The emergence of the C-H functionalization strategy in medicinal chemistry and drug discovery.
Jana R; Begam HM; Dinda E
Chem Commun (Camb); 2021 Oct; 57(83):10842-10866. PubMed ID: 34596175
[TBL] [Abstract][Full Text] [Related]
19. Drug rings database with web interface. A tool for identifying alternative chemical rings in lead discovery programs.
Lewell XQ; Jones AC; Bruce CL; Harper G; Jones MM; McLay IM; Bradshaw J
J Med Chem; 2003 Jul; 46(15):3257-74. PubMed ID: 12852756
[TBL] [Abstract][Full Text] [Related]
20. Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry.
Feher M; Schmidt JM
J Chem Inf Comput Sci; 2003; 43(1):218-27. PubMed ID: 12546556
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
