These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 19469544)

  • 1. Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases.
    Wong L; Tan SS; Lam Y; Melendez AJ
    J Med Chem; 2009 Jun; 52(12):3618-26. PubMed ID: 19469544
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pachastrissamine (jaspine B) and its stereoisomers inhibit sphingosine kinases and atypical protein kinase C.
    Yoshimitsu Y; Oishi S; Miyagaki J; Inuki S; Ohno H; Fujii N
    Bioorg Med Chem; 2011 Sep; 19(18):5402-8. PubMed ID: 21868240
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sphingosine kinase inhibitors: A patent review.
    Cao M; Ji C; Zhou Y; Huang W; Ni W; Tong X; Wei JF
    Int J Mol Med; 2018 May; 41(5):2450-2460. PubMed ID: 29484372
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Introduction of a Polar Functional Group to the Lipid Tail of 4-epi-Jaspine B Affects Sphingosine Kinase Isoform Selectivity.
    Inuki S; Miyagawa T; Oishi S; Ohno H
    Chem Pharm Bull (Tokyo); 2018; 66(9):866-872. PubMed ID: 30175743
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival.
    Maiti A; Takabe K; Hait NC
    Cell Signal; 2017 Apr; 32():85-92. PubMed ID: 28108260
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases.
    Hait NC; Oskeritzian CA; Paugh SW; Milstien S; Spiegel S
    Biochim Biophys Acta; 2006 Dec; 1758(12):2016-26. PubMed ID: 16996023
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.
    Patwardhan NN; Morris EA; Kharel Y; Raje MR; Gao M; Tomsig JL; Lynch KR; Santos WL
    J Med Chem; 2015 Feb; 58(4):1879-1899. PubMed ID: 25643074
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Drugging sphingosine kinases.
    Santos WL; Lynch KR
    ACS Chem Biol; 2015 Jan; 10(1):225-33. PubMed ID: 25384187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of Sphingosine Kinases Inhibitors: Challenges and Recent Developments.
    Magli E; Corvino A; Fiorino F; Frecentese F; Perissutti E; Saccone I; Santagada V; Caliendo G; Severino B
    Curr Pharm Des; 2019; 25(9):956-968. PubMed ID: 30947653
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.
    Evangelisti C; Evangelisti C; Buontempo F; Lonetti A; Orsini E; Chiarini F; Barata JT; Pyne S; Pyne NJ; Martelli AM
    Leukemia; 2016 Nov; 30(11):2142-2151. PubMed ID: 27461062
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and evaluation of 2-aminothiazole derivatives as sphingosine kinase inhibitors.
    Vogt D; Weber J; Ihlefeld K; Brüggerhoff A; Proschak E; Stark H
    Bioorg Med Chem; 2014 Oct; 22(19):5354-67. PubMed ID: 25150091
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sphingosine kinase, sphingosine-1-phosphate, and apoptosis.
    Maceyka M; Payne SG; Milstien S; Spiegel S
    Biochim Biophys Acta; 2002 Dec; 1585(2-3):193-201. PubMed ID: 12531554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets.
    Melendez AJ
    Biochim Biophys Acta; 2008 Jan; 1784(1):66-75. PubMed ID: 17913601
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling.
    Maceyka M; Milstien S; Spiegel S
    J Lipid Res; 2009 Apr; 50 Suppl(Suppl):S272-6. PubMed ID: 18987387
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of small-molecule inhibitors of sphingosine-1-phosphate signaling.
    Edmonds Y; Milstien S; Spiegel S
    Pharmacol Ther; 2011 Dec; 132(3):352-60. PubMed ID: 21906625
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.
    Lai WQ; Irwan AW; Goh HH; Howe HS; Yu DT; Valle-Oñate R; McInnes IB; Melendez AJ; Leung BP
    J Immunol; 2008 Dec; 181(11):8010-7. PubMed ID: 19017993
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.
    Kennedy AJ; Mathews TP; Kharel Y; Field SD; Moyer ML; East JE; Houck JD; Lynch KR; Macdonald TL
    J Med Chem; 2011 May; 54(10):3524-48. PubMed ID: 21495716
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.
    Kharel Y; Raje M; Gao M; Gellett AM; Tomsig JL; Lynch KR; Santos WL
    Biochem J; 2012 Oct; 447(1):149-57. PubMed ID: 22747486
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate.
    Kharel Y; Mathews TP; Gellett AM; Tomsig JL; Kennedy PC; Moyer ML; Macdonald TL; Lynch KR
    Biochem J; 2011 Dec; 440(3):345-53. PubMed ID: 21848514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rational design of SphK inhibitors using crystal structures aided by computer.
    Ding T; Zhi Y; Xie W; Yao Q; Liu B
    Eur J Med Chem; 2021 Mar; 213():113164. PubMed ID: 33454547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.