These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 19473969)

  • 1. Stabilization of the E* form turns thrombin into an anticoagulant.
    Bah A; Carrell CJ; Chen Z; Gandhi PS; Di Cera E
    J Biol Chem; 2009 Jul; 284(30):20034-40. PubMed ID: 19473969
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of the anticoagulant activity of thrombin mutant W215A/E217A.
    Gandhi PS; Page MJ; Chen Z; Bush-Pelc L; Di Cera E
    J Biol Chem; 2009 Sep; 284(36):24098-105. PubMed ID: 19586901
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of the anticoagulant slow form of thrombin.
    Pineda AO; Savvides SN; Waksman G; Di Cera E
    J Biol Chem; 2002 Oct; 277(43):40177-80. PubMed ID: 12205081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.
    Tanaka KA; Gruber A; Szlam F; Bush LA; Hanson SR; Di Cera E
    Blood Coagul Fibrinolysis; 2008 Jul; 19(5):465-8. PubMed ID: 18600103
    [No Abstract]   [Full Text] [Related]  

  • 5. Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex.
    Rezaie AR; Esmon CT
    Biochemistry; 1995 Sep; 34(38):12221-6. PubMed ID: 7547963
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket.
    Pineda AO; Chen ZW; Caccia S; Cantwell AM; Savvides SN; Waksman G; Mathews FS; Di Cera E
    J Biol Chem; 2004 Sep; 279(38):39824-8. PubMed ID: 15252033
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin.
    Rezaie AR; Yang L
    Proc Natl Acad Sci U S A; 2003 Oct; 100(21):12051-6. PubMed ID: 14523228
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Estimation of the possible recognition sites for thrombomodulin, procoagulant, and anticoagulant proteins around the active center of alpha-thrombin.
    Nishioka J; Taneda H; Suzuki K
    J Biochem; 1993 Jul; 114(1):148-55. PubMed ID: 8407867
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery.
    Carter WJ; Myles T; Gibbs CS; Leung LL; Huntington JA
    J Biol Chem; 2004 Jun; 279(25):26387-94. PubMed ID: 15075325
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing the activation of protein C by the thrombin-thrombomodulin complex using structural analysis, site-directed mutagenesis, and computer modeling.
    Knobe KE; Berntsdotter A; Shen L; Morser J; Dahlbäck B; Villoutreix BO
    Proteins; 1999 May; 35(2):218-34. PubMed ID: 10223294
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutation of Glu-80-->Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex.
    Rezaie AR; Mather T; Sussman F; Esmon CT
    J Biol Chem; 1994 Feb; 269(5):3151-4. PubMed ID: 7906267
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis studies toward understanding allostery in thrombin.
    Qureshi SH; Yang L; Manithody C; Iakhiaev AV; Rezaie AR
    Biochemistry; 2009 Sep; 48(34):8261-70. PubMed ID: 19640005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis of thrombomodulin activation of slow thrombin.
    Adams TE; Li W; Huntington JA
    J Thromb Haemost; 2009 Oct; 7(10):1688-95. PubMed ID: 19656282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. How Thrombomodulin Enables W215A/E217A Thrombin to Cleave Protein C but Not Fibrinogen.
    Peacock RB; McGrann T; Zaragoza S; Komives EA
    Biochemistry; 2022 Jan; 61(2):77-84. PubMed ID: 34978431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of thrombin in a self-inhibited conformation.
    Pineda AO; Chen ZW; Bah A; Garvey LC; Mathews FS; Di Cera E
    J Biol Chem; 2006 Oct; 281(43):32922-8. PubMed ID: 16954215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The thrombin epitope recognizing thrombomodulin is a highly cooperative hot spot in exosite I.
    Pineda AO; Cantwell AM; Bush LA; Rose T; Di Cera E
    J Biol Chem; 2002 Aug; 277(35):32015-9. PubMed ID: 12068020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutation of protease domain residues Lys37-39 in human protein C inhibits activation by the thrombomodulin-thrombin complex without affecting activation by free thrombin.
    Gerlitz B; Grinnell BW
    J Biol Chem; 1996 Sep; 271(37):22285-8. PubMed ID: 8798383
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction of thrombin des-ETW with antithrombin III, the Kunitz inhibitors, thrombomodulin and protein C. Structural link between the autolysis loop and the Tyr-Pro-Pro-Trp insertion of thrombin.
    Le Bonniec BF; Guinto ER; Esmon CT
    J Biol Chem; 1992 Sep; 267(27):19341-8. PubMed ID: 1326550
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C.
    Xu H; Bush LA; Pineda AO; Caccia S; Di Cera E
    J Biol Chem; 2005 Mar; 280(9):7956-61. PubMed ID: 15582990
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex.
    Fuentes-Prior P; Iwanaga Y; Huber R; Pagila R; Rumennik G; Seto M; Morser J; Light DR; Bode W
    Nature; 2000 Mar; 404(6777):518-25. PubMed ID: 10761923
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.