214 related articles for article (PubMed ID: 19478560)
1. Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence.
Demidenko ZN; Shtutman M; Blagosklonny MV
Cell Cycle; 2009 Jun; 8(12):1896-900. PubMed ID: 19478560
[TBL] [Abstract][Full Text] [Related]
2. Aging-suppressants: cellular senescence (hyperactivation) and its pharmacologic deceleration.
Blagosklonny MV
Cell Cycle; 2009 Jun; 8(12):1883-7. PubMed ID: 19448395
[TBL] [Abstract][Full Text] [Related]
3. Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway.
Fukazawa H; Noguchi K; Murakami Y; Uehara Y
Mol Cancer Ther; 2002 Mar; 1(5):303-9. PubMed ID: 12489846
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
Tsurutani J; West KA; Sayyah J; Gills JJ; Dennis PA
Cancer Res; 2005 Sep; 65(18):8423-32. PubMed ID: 16166321
[TBL] [Abstract][Full Text] [Related]
5. MEK drives cyclin D1 hyperelevation during geroconversion.
Leontieva OV; Demidenko ZN; Blagosklonny MV
Cell Death Differ; 2013 Sep; 20(9):1241-9. PubMed ID: 23852369
[TBL] [Abstract][Full Text] [Related]
6. At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence.
Demidenko ZN; Blagosklonny MV
Cell Cycle; 2009 Jun; 8(12):1901-4. PubMed ID: 19471118
[TBL] [Abstract][Full Text] [Related]
7. Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways.
Penuel E; Martin GS
Mol Biol Cell; 1999 Jun; 10(6):1693-703. PubMed ID: 10359590
[TBL] [Abstract][Full Text] [Related]
8. Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
Lasithiotakis KG; Sinnberg TW; Schittek B; Flaherty KT; Kulms D; Maczey E; Garbe C; Meier FE
J Invest Dermatol; 2008 Aug; 128(8):2013-23. PubMed ID: 18323781
[TBL] [Abstract][Full Text] [Related]
9. Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway.
Shegogue D; Trojanowska M
J Biol Chem; 2004 May; 279(22):23166-75. PubMed ID: 15047702
[TBL] [Abstract][Full Text] [Related]
10. U0126 reverses Ki-ras-mediated transformation by blocking both mitogen-activated protein kinase and p70 S6 kinase pathways.
Fukazawa H; Uehara Y
Cancer Res; 2000 Apr; 60(8):2104-7. PubMed ID: 10786668
[TBL] [Abstract][Full Text] [Related]
11. Activation of phosphatidylinositol 3-kinase, protein kinase B, and p70 S6 kinases in lipopolysaccharide-stimulated Raw 264.7 cells: differential effects of rapamycin, Ly294002, and wortmannin on nitric oxide production.
Salh B; Wagey R; Marotta A; Tao JS; Pelech S
J Immunol; 1998 Dec; 161(12):6947-54. PubMed ID: 9862729
[TBL] [Abstract][Full Text] [Related]
12. Synaptically driven phosphorylation of ribosomal protein S6 is differentially regulated at active synapses versus dendrites and cell bodies by MAPK and PI3K/mTOR signaling pathways.
Pirbhoy PS; Farris S; Steward O
Learn Mem; 2017 Aug; 24(8):341-357. PubMed ID: 28716954
[TBL] [Abstract][Full Text] [Related]
13. Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
Li W; Sumpio BE
Am J Physiol Heart Circ Physiol; 2005 Apr; 288(4):H1591-7. PubMed ID: 15591103
[TBL] [Abstract][Full Text] [Related]
14. Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients.
Chow S; Minden MD; Hedley DW
Exp Hematol; 2006 Sep; 34(9):1183-91. PubMed ID: 16939811
[TBL] [Abstract][Full Text] [Related]
15. Not only insulin stimulates mitochondriogenesis in muscle cells, but mitochondria are also essential for insulin-mediated myogenesis.
Pawlikowska P; Gajkowska B; Hocquette JF; Orzechowski A
Cell Prolif; 2006 Apr; 39(2):127-45. PubMed ID: 16542348
[TBL] [Abstract][Full Text] [Related]
16. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
Ikezoe T; Nishioka C; Bandobashi K; Yang Y; Kuwayama Y; Adachi Y; Takeuchi T; Koeffler HP; Taguchi H
Leuk Res; 2007 May; 31(5):673-82. PubMed ID: 17007924
[TBL] [Abstract][Full Text] [Related]
17. Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines.
Maeda N; Fu W; Ortin A; de las Heras M; Fan H
J Virol; 2005 Apr; 79(7):4440-50. PubMed ID: 15767444
[TBL] [Abstract][Full Text] [Related]
18. IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells.
Tuhácková Z; Sloncová E; Vojtechová M; Sovová V
Int J Mol Med; 2004 Apr; 13(4):601-5. PubMed ID: 15010863
[TBL] [Abstract][Full Text] [Related]
19. Akt2, but not Akt1 or Akt3 mediates pressure-stimulated serum-opsonized latex bead phagocytosis through activating mTOR and p70 S6 kinase.
Shiratsuchi H; Basson MD
J Cell Biochem; 2007 Oct; 102(2):353-67. PubMed ID: 17372934
[TBL] [Abstract][Full Text] [Related]
20. Targeting cancer stem cells in glioblastoma multiforme using mTOR inhibitors and the differentiating agent all-trans retinoic acid.
Friedman MD; Jeevan DS; Tobias M; Murali R; Jhanwar-Uniyal M
Oncol Rep; 2013 Oct; 30(4):1645-50. PubMed ID: 23877261
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
