105 related articles for article (PubMed ID: 19479254)
1. Phase I clinical and pharmacokinetic study of the glucose-conjugated cytotoxic agent D-19575 (glufosfamide) in patients with solid tumors.
Shimizu T; Okamoto I; Tamura K; Satoh T; Miyazaki M; Akashi Y; Ozaki T; Fukuoka M; Nakagawa K
Cancer Chemother Pharmacol; 2010 Jan; 65(2):243-50. PubMed ID: 19479254
[TBL] [Abstract][Full Text] [Related]
2. Phase I trial of 6-hour infusion of glufosfamide, a new alkylating agent with potentially enhanced selectivity for tumors that overexpress transmembrane glucose transporters: a study of the European Organization for Research and Treatment of Cancer Early Clinical Studies Group.
Briasoulis E; Judson I; Pavlidis N; Beale P; Wanders J; Groot Y; Veerman G; Schuessler M; Niebch G; Siamopoulos K; Tzamakou E; Rammou D; Wolf L; Walker R; Hanauske A
J Clin Oncol; 2000 Oct; 18(20):3535-44. PubMed ID: 11032596
[TBL] [Abstract][Full Text] [Related]
3. European Organization for Research and Treatment of Cancer (EORTC) open label phase II study on glufosfamide administered as a 60-minute infusion every 3 weeks in recurrent glioblastoma multiforme.
van den Bent MJ; Grisold W; Frappaz D; Stupp R; Desir JP; Lesimple T; Dittrich C; de Jonge MJ; Brandes A; Frenay M; Carpentier AF; Chollet P; Oliveira J; Baron B; Lacombe D; Schuessler M; Fumoleau P; ;
Ann Oncol; 2003 Dec; 14(12):1732-4. PubMed ID: 14630677
[TBL] [Abstract][Full Text] [Related]
4. Glufosfamide as a new oxazaphosphorine anticancer agent.
Mazur L; Opydo-Chanek M; Stojak M
Anticancer Drugs; 2011 Jul; 22(6):488-93. PubMed ID: 21427562
[TBL] [Abstract][Full Text] [Related]
5. Glufosfamide: beta-D-Glc-IPM, D 19575.
Drugs R D; 2005; 6(1):49-52. PubMed ID: 15801867
[TBL] [Abstract][Full Text] [Related]
6. Glufosfamide administered using a 1-hour infusion given as first-line treatment for advanced pancreatic cancer. A phase II trial of the EORTC-new drug development group.
Briasoulis E; Pavlidis N; Terret C; Bauer J; Fiedler W; Schöffski P; Raoul JL; Hess D; Selvais R; Lacombe D; Bachmann P; Fumoleau P
Eur J Cancer; 2003 Nov; 39(16):2334-40. PubMed ID: 14556925
[TBL] [Abstract][Full Text] [Related]
7. Glufosfamide administered by 1-hour infusion as a second-line treatment for advanced non-small cell lung cancer; a phase II trial of the EORTC-New Drug Development Group.
Giaccone G; Smit EF; de Jonge M; Dansin E; Briasoulis E; Ardizzoni A; Douillard JY; Spaeth D; Lacombe D; Baron B; Bachmann P; Fumoleau P;
Eur J Cancer; 2004 Mar; 40(5):667-72. PubMed ID: 15010066
[TBL] [Abstract][Full Text] [Related]
8. A Phase 1 dose-escalation trial of glufosfamide in combination with gemcitabine in solid tumors including pancreatic adenocarcinoma.
Chiorean EG; Dragovich T; Hamm J; Langmuir VK; Kroll S; Jung DT; Colowick AB; Tidmarsh GF; Loehrer PJ
Cancer Chemother Pharmacol; 2008 May; 61(6):1019-26. PubMed ID: 17661038
[TBL] [Abstract][Full Text] [Related]
9. Phase 1 study of the safety, tolerability, and pharmacokinetics of TH-302, a hypoxia-activated prodrug, in patients with advanced solid malignancies.
Weiss GJ; Infante JR; Chiorean EG; Borad MJ; Bendell JC; Molina JR; Tibes R; Ramanathan RK; Lewandowski K; Jones SF; Lacouture ME; Langmuir VK; Lee H; Kroll S; Burris HA
Clin Cancer Res; 2011 May; 17(9):2997-3004. PubMed ID: 21415214
[TBL] [Abstract][Full Text] [Related]
10. A phase I study of the dolastatin-15 analogue tasidotin (ILX651) administered intravenously daily for 5 consecutive days every 3 weeks in patients with advanced solid tumors.
Ebbinghaus S; Rubin E; Hersh E; Cranmer LD; Bonate PL; Fram RJ; Jekunen A; Weitman S; Hammond LA
Clin Cancer Res; 2005 Nov; 11(21):7807-16. PubMed ID: 16278403
[TBL] [Abstract][Full Text] [Related]
11. Design of new oxazaphosphorine anticancer drugs.
Liang J; Huang M; Duan W; Yu XQ; Zhou S
Curr Pharm Des; 2007; 13(9):963-78. PubMed ID: 17430192
[TBL] [Abstract][Full Text] [Related]
12. Phase I clinical trial and pharmacokinetic study of the spicamycin analog KRN5500 administered as a 1-hour intravenous infusion for five consecutive days to patients with refractory solid tumors.
Supko JG; Eder JP; Ryan DP; Seiden MV; Lynch TJ; Amrein PC; Kufe DW; Clark JW
Clin Cancer Res; 2003 Nov; 9(14):5178-86. PubMed ID: 14613997
[TBL] [Abstract][Full Text] [Related]
13. A phase I evaluation of multitargeted antifolate (MTA, LY231514), administered every 21 days, utilizing the modified continual reassessment method for dose escalation.
Rinaldi DA; Kuhn JG; Burris HA; Dorr FA; Rodriguez G; Eckhardt SG; Jones S; Woodworth JR; Baker S; Langley C; Mascorro D; Abrahams T; Von Hoff DD
Cancer Chemother Pharmacol; 1999; 44(5):372-80. PubMed ID: 10501910
[TBL] [Abstract][Full Text] [Related]
14. Phase I and pharmacokinetic study of irofulven administered weekly or biweekly in advanced solid tumor patients.
Alexandre J; Raymond E; Kaci MO; Brain EC; Lokiec F; Kahatt C; Faivre S; Yovine A; Goldwasser F; Smith SL; MacDonald JR; Misset JL; Cvitkovic E
Clin Cancer Res; 2004 May; 10(10):3377-85. PubMed ID: 15161692
[TBL] [Abstract][Full Text] [Related]
15. Phase I clinical and pharmacokinetic study of flavopiridol administered as a daily 1-hour infusion in patients with advanced neoplasms.
Tan AR; Headlee D; Messmann R; Sausville EA; Arbuck SG; Murgo AJ; Melillo G; Zhai S; Figg WD; Swain SM; Senderowicz AM
J Clin Oncol; 2002 Oct; 20(19):4074-82. PubMed ID: 12351605
[TBL] [Abstract][Full Text] [Related]
16. Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-hour continuous intravenous infusion in patients with solid malignancies.
Ryan DP; Supko JG; Eder JP; Seiden MV; Demetri G; Lynch TJ; Fischman AJ; Davis J; Jimeno J; Clark JW
Clin Cancer Res; 2001 Feb; 7(2):231-42. PubMed ID: 11234874
[TBL] [Abstract][Full Text] [Related]
17. Phase I and pharmacokinetic study of the dolastatin 10 analogue TZT-1027, given on days 1 and 8 of a 3-week cycle in patients with advanced solid tumors.
de Jonge MJ; van der Gaast A; Planting AS; van Doorn L; Lems A; Boot I; Wanders J; Satomi M; Verweij J
Clin Cancer Res; 2005 May; 11(10):3806-13. PubMed ID: 15897580
[TBL] [Abstract][Full Text] [Related]
18. Anticancer activity of stabilized palifosfamide in vivo: schedule effects, oral bioavailability, and enhanced activity with docetaxel and doxorubicin.
Jones B; Komarnitsky P; Miller GT; Amedio J; Wallner BP
Anticancer Drugs; 2012 Feb; 23(2):173-84. PubMed ID: 22027537
[TBL] [Abstract][Full Text] [Related]
19. Phase I and pharmacokinetic study of edotecarin, a novel topoisomerase I inhibitor, administered once every 3 weeks in patients with solid tumors.
Yamada Y; Tamura T; Yamamoto N; Shimoyama T; Ueda Y; Murakami H; Kusaba H; Kamiya Y; Saka H; Tanigawara Y; McGovren JP; Natsumeda Y
Cancer Chemother Pharmacol; 2006 Aug; 58(2):173-82. PubMed ID: 16308697
[TBL] [Abstract][Full Text] [Related]
20. D-19575--a sugar-linked isophosphoramide mustard derivative exploiting transmembrane glucose transport.
Pohl J; Bertram B; Hilgard P; Nowrousian MR; Stüben J; Wiessler M
Cancer Chemother Pharmacol; 1995; 35(5):364-70. PubMed ID: 7850916
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
