136 related articles for article (PubMed ID: 19482478)
1. Retinoid receptor subtype-selective modulators through synthetic modifications of RARgamma agonists.
Alvarez S; Alvarez R; Khanwalkar H; Germain P; Lemaire G; Rodríguez-Barrios F; Gronemeyer H; de Lera AR
Bioorg Med Chem; 2009 Jul; 17(13):4345-59. PubMed ID: 19482478
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists.
Géhin M; Vivat V; Wurtz JM; Losson R; Chambon P; Moras D; Gronemeyer H
Chem Biol; 1999 Aug; 6(8):519-29. PubMed ID: 10421757
[TBL] [Abstract][Full Text] [Related]
3. Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cells.
Koo JS; Jetten AM; Belloni P; Yoon JH; Kim YD; Nettesheim P
Biochem J; 1999 Mar; 338 ( Pt 2)(Pt 2):351-7. PubMed ID: 10024510
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids.
Dhar A; Liu S; Klucik J; Berlin KD; Madler MM; Lu S; Ivey RT; Zacheis D; Brown CW; Nelson EC; Birckbichler PJ; Benbrook DM
J Med Chem; 1999 Sep; 42(18):3602-14. PubMed ID: 10479291
[TBL] [Abstract][Full Text] [Related]
5. C3 halogen and c8'' substituents on stilbene arotinoids modulate retinoic Acid receptor subtype function.
Alvarez S; Khanwalkar H; Alvarez R; Erb C; Martínez C; Rodríguez-Barrios F; Germain P; Gronemeyer H; de Lera AR
ChemMedChem; 2009 Oct; 4(10):1630-40. PubMed ID: 19670208
[TBL] [Abstract][Full Text] [Related]
6. Pyrazine arotinoids with inverse agonist activities on the retinoid and rexinoid receptors.
García J; Khanwalkar H; Pereira R; Erb C; Voegel JJ; Collette P; Mauvais P; Bourguet W; Gronemeyer H; de Lera AR
Chembiochem; 2009 May; 10(7):1252-9. PubMed ID: 19343742
[TBL] [Abstract][Full Text] [Related]
7. Retinoic acid receptor beta,gamma-selective ligands: synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids.
Yu KL; Spinazze P; Ostrowski J; Currier SJ; Pack EJ; Hammer L; Roalsvig T; Honeyman JA; Tortolani DR; Reczek PR; Mansuri MM; Starrett JE
J Med Chem; 1996 Jun; 39(12):2411-21. PubMed ID: 8691435
[TBL] [Abstract][Full Text] [Related]
8. Marked improvement induced in photoaged skin of hairless mouse by ER36009, a novel RARgamma-specific retinoid, but not by ER35794, an RXR-selective agonist.
Sakuta T; Kanayama T
Int J Dermatol; 2006 Nov; 45(11):1288-95. PubMed ID: 17076708
[TBL] [Abstract][Full Text] [Related]
9. Design of selective nuclear receptor modulators: RAR and RXR as a case study.
de Lera AR; Bourguet W; Altucci L; Gronemeyer H
Nat Rev Drug Discov; 2007 Oct; 6(10):811-20. PubMed ID: 17906643
[TBL] [Abstract][Full Text] [Related]
10. Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.
Klaholz BP; Mitschler A; Moras D
J Mol Biol; 2000 Sep; 302(1):155-70. PubMed ID: 10964567
[TBL] [Abstract][Full Text] [Related]
11. Determinants of retinoid X receptor transcriptional antagonism.
Cavasotto CN; Liu G; James SY; Hobbs PD; Peterson VJ; Bhattacharya AA; Kolluri SK; Zhang XK; Leid M; Abagyan R; Liddington RC; Dawson MI
J Med Chem; 2004 Aug; 47(18):4360-72. PubMed ID: 15317450
[TBL] [Abstract][Full Text] [Related]
12. A conserved retinoid X receptor (RXR) from the mollusk Biomphalaria glabrata transactivates transcription in the presence of retinoids.
Bouton D; Escriva H; de Mendonça RL; Glineur C; Bertin B; Noël C; Robinson-Rechavi M; de Groot A; Cornette J; Laudet V; Pierce RJ
J Mol Endocrinol; 2005 Apr; 34(2):567-82. PubMed ID: 15821117
[TBL] [Abstract][Full Text] [Related]
13. Synthetic retinoids: structure-activity relationships.
Barnard JH; Collings JC; Whiting A; Przyborski SA; Marder TB
Chemistry; 2009 Nov; 15(43):11430-42. PubMed ID: 19821467
[TBL] [Abstract][Full Text] [Related]
14. RARbeta ligand-binding domain bound to an SRC-1 co-activator peptide: purification, crystallization and preliminary X-ray diffraction analysis.
Kammerer S; Germain P; Flaig R; Peluso-Iltis C; Mitschler A; Rochel N; Gronemeyer H; Moras D
Acta Crystallogr D Biol Crystallogr; 2004 Nov; 60(Pt 11):2048-50. PubMed ID: 15502323
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and evaluation of retinoids with novel bulky hydrophobic partial structures.
Amano Y; Noguchi M; Nakagomi M; Muratake H; Fukasawa H; Shudo K
Bioorg Med Chem; 2013 Jul; 21(14):4342-50. PubMed ID: 23685180
[TBL] [Abstract][Full Text] [Related]
16. Silicon analogues of the RXR-selective retinoid agonist SR11237 (BMS649): chemistry and biology.
Lippert WP; Burschka C; Götz K; Kaupp M; Ivanova D; Gaudon C; Sato Y; Antony P; Rochel N; Moras D; Gronemeyer H; Tacke R
ChemMedChem; 2009 Jul; 4(7):1143-52. PubMed ID: 19496083
[TBL] [Abstract][Full Text] [Related]
17. RAR and RXR modulation in cancer and metabolic disease.
Altucci L; Leibowitz MD; Ogilvie KM; de Lera AR; Gronemeyer H
Nat Rev Drug Discov; 2007 Oct; 6(10):793-810. PubMed ID: 17906642
[TBL] [Abstract][Full Text] [Related]
18. Disila-analogues of the synthetic retinoids EC23 and TTNN: synthesis, structure and biological evaluation.
Gluyas JB; Burschka C; Dörrich S; Vallet J; Gronemeyer H; Tacke R
Org Biomol Chem; 2012 Sep; 10(34):6914-29. PubMed ID: 22814352
[TBL] [Abstract][Full Text] [Related]
19. Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles.
Pérez-Rodríguez S; Ortiz MA; Pereira R; Rodríguez-Barrios F; de Lera AR; Piedrafita FJ
Eur J Med Chem; 2009 Jun; 44(6):2434-46. PubMed ID: 19216008
[TBL] [Abstract][Full Text] [Related]
20. Mechanism of regulation and suppression of melanoma invasiveness by novel retinoic acid receptor-gamma target gene carbohydrate sulfotransferase 10.
Zhao X; Graves C; Ames SJ; Fisher DE; Spanjaard RA
Cancer Res; 2009 Jun; 69(12):5218-25. PubMed ID: 19470764
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]