170 related articles for article (PubMed ID: 19488402)
21. Nuclear relocation of normal huntingtin.
Tao T; Tartakoff AM
Traffic; 2001 Jun; 2(6):385-94. PubMed ID: 11389766
[TBL] [Abstract][Full Text] [Related]
22. Aggregation in Huntington's disease: insights through modelling.
Cajavec B; Bernard S; Herzel H
Genome Inform; 2005; 16(1):262-71. PubMed ID: 16362929
[TBL] [Abstract][Full Text] [Related]
23. NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
Solt LA; Madge LA; May MJ
J Biol Chem; 2009 Oct; 284(40):27596-608. PubMed ID: 19666475
[TBL] [Abstract][Full Text] [Related]
24. Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.
Busch A; Engemann S; Lurz R; Okazawa H; Lehrach H; Wanker EE
J Biol Chem; 2003 Oct; 278(42):41452-61. PubMed ID: 12888569
[TBL] [Abstract][Full Text] [Related]
25. Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblasts.
Sawa A; Nagata E; Sutcliffe S; Dulloor P; Cascio MB; Ozeki Y; Roy S; Ross CA; Snyder SH
Neurobiol Dis; 2005 Nov; 20(2):267-74. PubMed ID: 15890517
[TBL] [Abstract][Full Text] [Related]
26. Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons.
Anne SL; Saudou F; Humbert S
J Neurosci; 2007 Jul; 27(27):7318-28. PubMed ID: 17611284
[TBL] [Abstract][Full Text] [Related]
27. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
Ratovitski T; Arbez N; Stewart JC; Chighladze E; Ross CA
Cell Cycle; 2015; 14(11):1716-29. PubMed ID: 25927346
[TBL] [Abstract][Full Text] [Related]
28. IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway.
Adli M; Merkhofer E; Cogswell P; Baldwin AS
PLoS One; 2010 Feb; 5(2):e9428. PubMed ID: 20195534
[TBL] [Abstract][Full Text] [Related]
29. Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
Cho KJ; Lee BI; Cheon SY; Kim HW; Kim HJ; Kim GW
Neuroscience; 2009 Nov; 163(4):1128-34. PubMed ID: 19646509
[TBL] [Abstract][Full Text] [Related]
30. Inducing huntingtin inclusion formation in primary neuronal cell culture and in vivo by high-capacity adenoviral vectors expressing truncated and full-length huntingtin with polyglutamine expansion.
Huang B; Schiefer J; Sass C; Kosinski CM; Kochanek S
J Gene Med; 2008 Mar; 10(3):269-79. PubMed ID: 18067195
[TBL] [Abstract][Full Text] [Related]
31. Interleukin-1-induced NF-kappaB activation is NEMO-dependent but does not require IKKbeta.
Solt LA; Madge LA; Orange JS; May MJ
J Biol Chem; 2007 Mar; 282(12):8724-33. PubMed ID: 17244613
[TBL] [Abstract][Full Text] [Related]
32. Experimental mutagenesis of huntingtin to map cleavage sites: different outcomes in cell and mouse models.
Tebbenkamp AT; Xu G; Siemienski ZB; Janus C; Fromholt SE; Brown HH; Swing D; Tessarollo L; Borchelt DR
J Huntingtons Dis; 2014; 3(1):73-86. PubMed ID: 25062766
[TBL] [Abstract][Full Text] [Related]
33. Amyloid precursor protein binding protein Fe65 is cleaved by caspases during DNA damage-induced apoptosis.
Saeki K; Nose Y; Hirao N; Takasawa R; Tanuma S
Biol Pharm Bull; 2011; 34(2):290-4. PubMed ID: 21415543
[TBL] [Abstract][Full Text] [Related]
34. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Orr AL; Li S; Wang CE; Li H; Wang J; Rong J; Xu X; Mastroberardino PG; Greenamyre JT; Li XJ
J Neurosci; 2008 Mar; 28(11):2783-92. PubMed ID: 18337408
[TBL] [Abstract][Full Text] [Related]
35. Adenovirus vector-based in vitro neuronal cell model for Huntington's disease with human disease-like differential aggregation and degeneration.
Dong X; Zong S; Witting A; Lindenberg KS; Kochanek S; Huang B
J Gene Med; 2012 Jul; 14(7):468-81. PubMed ID: 22700462
[TBL] [Abstract][Full Text] [Related]
36. Huntingtin is degraded to small fragments by calpain after ischemic injury.
Kim M; Roh JK; Yoon BW; Kang L; Kim YJ; Aronin N; DiFiglia M
Exp Neurol; 2003 Sep; 183(1):109-15. PubMed ID: 12957494
[TBL] [Abstract][Full Text] [Related]
37. Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
Boudreau RL; McBride JL; Martins I; Shen S; Xing Y; Carter BJ; Davidson BL
Mol Ther; 2009 Jun; 17(6):1053-63. PubMed ID: 19240687
[TBL] [Abstract][Full Text] [Related]
38. Stimulation of NeuroD activity by huntingtin and huntingtin-associated proteins HAP1 and MLK2.
Marcora E; Gowan K; Lee JE
Proc Natl Acad Sci U S A; 2003 Aug; 100(16):9578-83. PubMed ID: 12881483
[TBL] [Abstract][Full Text] [Related]
39. Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models.
Leyva MJ; Degiacomo F; Kaltenbach LS; Holcomb J; Zhang N; Gafni J; Park H; Lo DC; Salvesen GS; Ellerby LM; Ellman JA
Chem Biol; 2010 Nov; 17(11):1189-200. PubMed ID: 21095569
[TBL] [Abstract][Full Text] [Related]
40. Wild-type huntingtin plays a role in brain development and neuronal survival.
Reiner A; Dragatsis I; Zeitlin S; Goldowitz D
Mol Neurobiol; 2003 Dec; 28(3):259-76. PubMed ID: 14709789
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]