These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 19494119)

  • 1. Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53.
    Sykes SM; Stanek TJ; Frank A; Murphy ME; McMahon SB
    J Biol Chem; 2009 Jul; 284(30):20197-205. PubMed ID: 19494119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
    J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis.
    Adlakha YK; Saini N
    Cell Death Dis; 2013 Mar; 4(3):e542. PubMed ID: 23492773
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria.
    Matissek KJ; Mossalam M; Okal A; Lim CS
    Mol Pharm; 2013 Oct; 10(10):3592-602. PubMed ID: 23968395
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis.
    Nieminen AI; Eskelinen VM; Haikala HM; Tervonen TA; Yan Y; Partanen JI; Klefström J
    Proc Natl Acad Sci U S A; 2013 May; 110(20):E1839-48. PubMed ID: 23589839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.
    Ha JH; Shin JS; Yoon MK; Lee MS; He F; Bae KH; Yoon HS; Lee CK; Park SG; Muto Y; Chi SW
    J Biol Chem; 2013 Mar; 288(10):7387-98. PubMed ID: 23316052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
    Senft D; Weber A; Saathoff F; Berking C; Heppt MV; Kammerbauer C; Rothenfusser S; Kellner S; Kurgyis Z; Besch R; Häcker G
    Cell Death Dis; 2015 Nov; 6(11):e1996. PubMed ID: 26610208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.
    Han J; Goldstein LA; Hou W; Gastman BR; Rabinowich H
    J Biol Chem; 2010 Jul; 285(29):22473-83. PubMed ID: 20404322
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acetylation of p53 Protein at Lysine 120 Up-regulates Apaf-1 Protein and Sensitizes the Mitochondrial Apoptotic Pathway.
    Yun T; Yu K; Yang S; Cui Y; Wang Z; Ren H; Chen S; Li L; Liu X; Fang M; Jiang X
    J Biol Chem; 2016 Apr; 291(14):7386-95. PubMed ID: 26851285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL.
    Sot B; Freund SM; Fersht AR
    J Biol Chem; 2007 Oct; 282(40):29193-200. PubMed ID: 17699158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The tetramerization domain of p53 is required for efficient BAK oligomerization.
    Pietsch EC; Leu JI; Frank A; Dumont P; George DL; Murphy ME
    Cancer Biol Ther; 2007 Oct; 6(10):1576-83. PubMed ID: 17895645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
    Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
    Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between Puma and Mcl-1.
    Nakajima W; Tanaka N
    Biochem Biophys Res Commun; 2011 Oct; 413(4):643-8. PubMed ID: 21945433
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anti-apoptosis proteins Mcl-1 and Bcl-xL have different p53-binding profiles.
    Yao H; Mi S; Gong W; Lin J; Xu N; Perrett S; Xia B; Wang J; Feng Y
    Biochemistry; 2013 Sep; 52(37):6324-34. PubMed ID: 23977882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.
    Zhang X; Li CF; Zhang L; Wu CY; Han L; Jin G; Rezaeian AH; Han F; Liu C; Xu C; Xu X; Huang CY; Tsai FJ; Tsai CH; Watabe K; Lin HK
    Mol Cell; 2016 Nov; 64(4):803-814. PubMed ID: 27818144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation.
    Gogna R; Madan E; Khan M; Pati U; Kuppusamy P
    EMBO Mol Med; 2013 Nov; 5(11):1662-83. PubMed ID: 24096875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain.
    Mellert H; Sykes SM; Murphy ME; McMahon SB
    Cell Cycle; 2007 Jun; 6(11):1304-6. PubMed ID: 17534149
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain.
    Pietsch EC; Perchiniak E; Canutescu AA; Wang G; Dunbrack RL; Murphy ME
    J Biol Chem; 2008 Jul; 283(30):21294-304. PubMed ID: 18524770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of HA14-1 on apoptosis-regulating proteins in HeLa cells.
    Rehman K; Tariq M; Akash MS; Gillani Z; Qazi MH
    Chem Biol Drug Des; 2014 Mar; 83(3):317-23. PubMed ID: 24118733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.