BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 19494119)

  • 1. Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53.
    Sykes SM; Stanek TJ; Frank A; Murphy ME; McMahon SB
    J Biol Chem; 2009 Jul; 284(30):20197-205. PubMed ID: 19494119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
    J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis.
    Adlakha YK; Saini N
    Cell Death Dis; 2013 Mar; 4(3):e542. PubMed ID: 23492773
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria.
    Matissek KJ; Mossalam M; Okal A; Lim CS
    Mol Pharm; 2013 Oct; 10(10):3592-602. PubMed ID: 23968395
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis.
    Nieminen AI; Eskelinen VM; Haikala HM; Tervonen TA; Yan Y; Partanen JI; Klefström J
    Proc Natl Acad Sci U S A; 2013 May; 110(20):E1839-48. PubMed ID: 23589839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.
    Ha JH; Shin JS; Yoon MK; Lee MS; He F; Bae KH; Yoon HS; Lee CK; Park SG; Muto Y; Chi SW
    J Biol Chem; 2013 Mar; 288(10):7387-98. PubMed ID: 23316052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
    Senft D; Weber A; Saathoff F; Berking C; Heppt MV; Kammerbauer C; Rothenfusser S; Kellner S; Kurgyis Z; Besch R; Häcker G
    Cell Death Dis; 2015 Nov; 6(11):e1996. PubMed ID: 26610208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.
    Han J; Goldstein LA; Hou W; Gastman BR; Rabinowich H
    J Biol Chem; 2010 Jul; 285(29):22473-83. PubMed ID: 20404322
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acetylation of p53 Protein at Lysine 120 Up-regulates Apaf-1 Protein and Sensitizes the Mitochondrial Apoptotic Pathway.
    Yun T; Yu K; Yang S; Cui Y; Wang Z; Ren H; Chen S; Li L; Liu X; Fang M; Jiang X
    J Biol Chem; 2016 Apr; 291(14):7386-95. PubMed ID: 26851285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL.
    Sot B; Freund SM; Fersht AR
    J Biol Chem; 2007 Oct; 282(40):29193-200. PubMed ID: 17699158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The tetramerization domain of p53 is required for efficient BAK oligomerization.
    Pietsch EC; Leu JI; Frank A; Dumont P; George DL; Murphy ME
    Cancer Biol Ther; 2007 Oct; 6(10):1576-83. PubMed ID: 17895645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
    Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
    Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between Puma and Mcl-1.
    Nakajima W; Tanaka N
    Biochem Biophys Res Commun; 2011 Oct; 413(4):643-8. PubMed ID: 21945433
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anti-apoptosis proteins Mcl-1 and Bcl-xL have different p53-binding profiles.
    Yao H; Mi S; Gong W; Lin J; Xu N; Perrett S; Xia B; Wang J; Feng Y
    Biochemistry; 2013 Sep; 52(37):6324-34. PubMed ID: 23977882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.
    Zhang X; Li CF; Zhang L; Wu CY; Han L; Jin G; Rezaeian AH; Han F; Liu C; Xu C; Xu X; Huang CY; Tsai FJ; Tsai CH; Watabe K; Lin HK
    Mol Cell; 2016 Nov; 64(4):803-814. PubMed ID: 27818144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation.
    Gogna R; Madan E; Khan M; Pati U; Kuppusamy P
    EMBO Mol Med; 2013 Nov; 5(11):1662-83. PubMed ID: 24096875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain.
    Mellert H; Sykes SM; Murphy ME; McMahon SB
    Cell Cycle; 2007 Jun; 6(11):1304-6. PubMed ID: 17534149
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain.
    Pietsch EC; Perchiniak E; Canutescu AA; Wang G; Dunbrack RL; Murphy ME
    J Biol Chem; 2008 Jul; 283(30):21294-304. PubMed ID: 18524770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of HA14-1 on apoptosis-regulating proteins in HeLa cells.
    Rehman K; Tariq M; Akash MS; Gillani Z; Qazi MH
    Chem Biol Drug Des; 2014 Mar; 83(3):317-23. PubMed ID: 24118733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.