BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 19495690)

  • 1. Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi.
    Towne C; Aebischer P
    Methods Mol Biol; 2009; 555():87-108. PubMed ID: 19495690
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice.
    Towne C; Raoul C; Schneider BL; Aebischer P
    Mol Ther; 2008 Jun; 16(6):1018-25. PubMed ID: 18414477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model.
    Ralph GS; Radcliffe PA; Day DM; Carthy JM; Leroux MA; Lee DC; Wong LF; Bilsland LG; Greensmith L; Kingsman SM; Mitrophanous KA; Mazarakis ND; Azzouz M
    Nat Med; 2005 Apr; 11(4):429-33. PubMed ID: 15768029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis.
    Wang H; Yang B; Qiu L; Yang C; Kramer J; Su Q; Guo Y; Brown RH; Gao G; Xu Z
    Hum Mol Genet; 2014 Feb; 23(3):668-81. PubMed ID: 24108104
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.
    Raoul C; Abbas-Terki T; Bensadoun JC; Guillot S; Haase G; Szulc J; Henderson CE; Aebischer P
    Nat Med; 2005 Apr; 11(4):423-8. PubMed ID: 15768028
    [TBL] [Abstract][Full Text] [Related]  

  • 6. VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.
    Azzouz M; Ralph GS; Storkebaum E; Walmsley LE; Mitrophanous KA; Kingsman SM; Carmeliet P; Mazarakis ND
    Nature; 2004 May; 429(6990):413-7. PubMed ID: 15164063
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice.
    Towne C; Setola V; Schneider BL; Aebischer P
    Mol Ther; 2011 Feb; 19(2):274-83. PubMed ID: 21102563
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adeno-associated virus-mediated delivery of a recombinant single-chain antibody against misfolded superoxide dismutase for treatment of amyotrophic lateral sclerosis.
    Patel P; Kriz J; Gravel M; Soucy G; Bareil C; Gravel C; Julien JP
    Mol Ther; 2014 Mar; 22(3):498-510. PubMed ID: 24394188
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNAi therapy: dominant disease gene gets silenced.
    Xu Z; Xia XG
    Gene Ther; 2005 Aug; 12(15):1159-60. PubMed ID: 15858609
    [No Abstract]   [Full Text] [Related]  

  • 10. Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS.
    Foust KD; Salazar DL; Likhite S; Ferraiuolo L; Ditsworth D; Ilieva H; Meyer K; Schmelzer L; Braun L; Cleveland DW; Kaspar BK
    Mol Ther; 2013 Dec; 21(12):2148-59. PubMed ID: 24008656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cervical spinal cord delivery of a rabies G protein pseudotyped lentiviral vector in the SOD-1 transgenic mouse. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004.
    Tanase K; Teng Q; Krishnaney AA; Liu JK; Garrity-Moses ME; Boulis NM
    J Neurosurg Spine; 2004 Jul; 1(1):128-36. PubMed ID: 15291033
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis.
    Wang LJ; Lu YY; Muramatsu S; Ikeguchi K; Fujimoto K; Okada T; Mizukami H; Matsushita T; Hanazono Y; Kume A; Nagatsu T; Ozawa K; Nakano I
    J Neurosci; 2002 Aug; 22(16):6920-8. PubMed ID: 12177190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.
    Ayers JI; Fromholt S; Sinyavskaya O; Siemienski Z; Rosario AM; Li A; Crosby KW; Cruz PE; DiNunno NM; Janus C; Ceballos-Diaz C; Borchelt DR; Golde TE; Chakrabarty P; Levites Y
    Mol Ther; 2015 Jan; 23(1):53-62. PubMed ID: 25228069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Slow Intrathecal Injection of rAAVrh10 Enhances its Transduction of Spinal Cord and Therapeutic Efficacy in a Mutant SOD1 Model of ALS.
    Li D; Liu C; Yang C; Wang D; Wu D; Qi Y; Su Q; Gao G; Xu Z; Guo Y
    Neuroscience; 2017 Dec; 365():192-205. PubMed ID: 29024785
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis.
    Miller TM; Kaspar BK; Kops GJ; Yamanaka K; Christian LJ; Gage FH; Cleveland DW
    Ann Neurol; 2005 May; 57(5):773-6. PubMed ID: 15852369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AAV6-mediated gene silencing fALS short.
    Mandel RJ; Lowenstein PR; Byrne BJ
    Mol Ther; 2011 Feb; 19(2):231-3. PubMed ID: 21289637
    [No Abstract]   [Full Text] [Related]  

  • 17. Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis.
    Nanou A; Higginbottom A; Valori CF; Wyles M; Ning K; Shaw P; Azzouz M
    Mol Ther; 2013 Aug; 21(8):1486-96. PubMed ID: 23732987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model.
    Stoica L; Todeasa SH; Cabrera GT; Salameh JS; ElMallah MK; Mueller C; Brown RH; Sena-Esteves M
    Ann Neurol; 2016 Apr; 79(4):687-700. PubMed ID: 26891182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.
    Borel F; Gernoux G; Cardozo B; Metterville JP; Toro Cabrera GC; Song L; Su Q; Gao GP; Elmallah MK; Brown RH; Mueller C
    Hum Gene Ther; 2016 Jan; 27(1):19-31. PubMed ID: 26710998
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.
    Xia XG; Zhou H; Zhou S; Yu Y; Wu R; Xu Z
    J Neurochem; 2005 Jan; 92(2):362-7. PubMed ID: 15663483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.