BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

547 related articles for article (PubMed ID: 19496619)

  • 1. Novel molecular mechanism for actinomycin D activity as an oncogenic promoter G-quadruplex binder.
    Kang HJ; Park HJ
    Biochemistry; 2009 Aug; 48(31):7392-8. PubMed ID: 19496619
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigating actinomycin D binding to G-quadruplex, i-motif and double-stranded DNA in 27-nt segment of c-MYC gene promoter.
    Niknezhad Z; Hassani L; Norouzi D
    Mater Sci Eng C Mater Biol Appl; 2016 Jan; 58():1188-93. PubMed ID: 26478420
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex.
    Ou TM; Lin J; Lu YJ; Hou JQ; Tan JH; Chen SH; Li Z; Li YP; Li D; Gu LQ; Huang ZS
    J Med Chem; 2011 Aug; 54(16):5671-9. PubMed ID: 21774525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
    Ou TM; Lu YJ; Zhang C; Huang ZS; Wang XD; Tan JH; Chen Y; Ma DL; Wong KY; Tang JC; Chan AS; Gu LQ
    J Med Chem; 2007 Apr; 50(7):1465-74. PubMed ID: 17346034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer.
    Chan DS; Yang H; Kwan MH; Cheng Z; Lee P; Bai LP; Jiang ZH; Wong CY; Fong WF; Leung CH; Ma DL
    Biochimie; 2011 Jun; 93(6):1055-64. PubMed ID: 21377506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression.
    Wu P; Ma DL; Leung CH; Yan SC; Zhu N; Abagyan R; Che CM
    Chemistry; 2009 Dec; 15(47):13008-21. PubMed ID: 19876976
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-affinity homologous peptide nucleic acid probes for targeting a quadruplex-forming sequence from a MYC promoter element.
    Roy S; Tanious FA; Wilson WD; Ly DH; Armitage BA
    Biochemistry; 2007 Sep; 46(37):10433-43. PubMed ID: 17718513
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Disubstituted 1,8-dipyrazolcarbazole derivatives as a new type of c-myc G-quadruplex binding ligands.
    Chen WJ; Zhou CX; Yao PF; Wang XX; Tan JH; Li D; Ou TM; Gu LQ; Huang ZS
    Bioorg Med Chem; 2012 May; 20(9):2829-36. PubMed ID: 22484007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Water regulation of actinomycin-D binding to DNA: the interplay among drug affinity, DNA long-range conformation, and hydration.
    Ruggiero Neto J; Colombo MF
    Biopolymers; 2000 Jan; 53(1):46-59. PubMed ID: 10644950
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA.
    Wang P; Leung CH; Ma DL; Yan SC; Che CM
    Chemistry; 2010 Jun; 16(23):6900-11. PubMed ID: 20437426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Silencing c-MYC expression by targeting quadruplex in P1 promoter using locked nucleic acid trap.
    Kumar N; Patowary A; Sivasubbu S; Petersen M; Maiti S
    Biochemistry; 2008 Dec; 47(50):13179-88. PubMed ID: 19053274
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Furan based cyclic homo-oligopeptides bind G-quadruplex selectively and repress c-MYC transcription.
    Agarwal T; Roy S; Chakraborty TK; Maiti S
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4346-9. PubMed ID: 20615700
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of the equilibrium between G-quadruplex and duplex DNA in promoter of human c-myc oncogene by a pyrene derivative.
    Zhang Z; He X; Yuan G
    Int J Biol Macromol; 2011 Dec; 49(5):1173-6. PubMed ID: 21683090
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel interaction of the Z-DNA binding domain of human ADAR1 with the oncogenic c-Myc promoter G-quadruplex.
    Kang HJ; Le TV; Kim K; Hur J; Kim KK; Park HJ
    J Mol Biol; 2014 Jul; 426(14):2594-604. PubMed ID: 24813121
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc.
    Ma Y; Ou TM; Hou JQ; Lu YJ; Tan JH; Gu LQ; Huang ZS
    Bioorg Med Chem; 2008 Aug; 16(16):7582-91. PubMed ID: 18674916
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.
    Siddiqui-Jain A; Grand CL; Bearss DJ; Hurley LH
    Proc Natl Acad Sci U S A; 2002 Sep; 99(18):11593-8. PubMed ID: 12195017
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In silico identification of novel ligands for G-quadruplex in the c-MYC promoter.
    Kang HJ; Park HJ
    J Comput Aided Mol Des; 2015 Apr; 29(4):339-48. PubMed ID: 25527072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Drug targeting of the c-MYC promoter to repress gene expression via a G-quadruplex silencer element.
    Hurley LH; Von Hoff DD; Siddiqui-Jain A; Yang D
    Semin Oncol; 2006 Aug; 33(4):498-512. PubMed ID: 16890804
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective recognition of oncogene promoter G-quadruplexes by Mg2+.
    Yan YY; Lin J; Ou TM; Tan JH; Li D; Gu LQ; Huang ZS
    Biochem Biophys Res Commun; 2010 Nov; 402(4):614-8. PubMed ID: 20971074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spontaneous DNA lesions modulate DNA structural transitions occurring at nuclease hypersensitive element III(1) of the human c-myc proto-oncogene.
    Beckett J; Burns J; Broxson C; Tornaletti S
    Biochemistry; 2012 Jul; 51(26):5257-68. PubMed ID: 22667821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.