BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

301 related articles for article (PubMed ID: 19498041)

  • 1. Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor.
    Sykes DA; Dowling MR; Charlton SJ
    Mol Pharmacol; 2009 Sep; 76(3):543-51. PubMed ID: 19498041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An investigation of whether agonist-selective receptor conformations occur with respect to M2 and M4 muscarinic acetylcholine receptor signalling via Gi/o and Gs proteins.
    Mistry R; Dowling MR; Challiss RA
    Br J Pharmacol; 2005 Feb; 144(4):566-75. PubMed ID: 15655507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interactions of agonists with M2 and M4 muscarinic receptor subtypes mediating cyclic AMP inhibition.
    McKinney M; Miller JH; Gibson VA; Nickelson L; Aksoy S
    Mol Pharmacol; 1991 Dec; 40(6):1014-22. PubMed ID: 1722002
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual effects of muscarinic M(2) acetylcholine receptors on the synthesis of cyclic AMP in CHO cells: dependence on time, receptor density and receptor agonists.
    Michal P; Lysíková M; Tucek S
    Br J Pharmacol; 2001 Mar; 132(6):1217-28. PubMed ID: 11250872
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.
    Jakubík J; El-Fakahany EE; Dolezal V
    Mol Pharmacol; 2006 Aug; 70(2):656-66. PubMed ID: 16675658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced high-affinity agonist binding at the M(1) muscarinic receptor in Alzheimer's disease brain: differential sensitivity to agonists and divalent cations.
    Ladner CJ; Lee JM
    Exp Neurol; 1999 Aug; 158(2):451-8. PubMed ID: 10415152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.
    May LT; Avlani VA; Langmead CJ; Herdon HJ; Wood MD; Sexton PM; Christopoulos A
    Mol Pharmacol; 2007 Aug; 72(2):463-76. PubMed ID: 17525129
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo.
    Schrage R; Holze J; Klöckner J; Balkow A; Klause AS; Schmitz AL; De Amici M; Kostenis E; Tränkle C; Holzgrabe U; Mohr K
    Biochem Pharmacol; 2014 Aug; 90(3):307-19. PubMed ID: 24863257
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors.
    Olianas MC; Adem A; Karlsson E; Onali P
    Eur J Pharmacol; 2004 Mar; 487(1-3):65-72. PubMed ID: 15033377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human colon cancer cell proliferation mediated by the M3 muscarinic cholinergic receptor.
    Frucht H; Jensen RT; Dexter D; Yang WL; Xiao Y
    Clin Cancer Res; 1999 Sep; 5(9):2532-9. PubMed ID: 10499630
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy.
    Jakubík J; Janíčková H; El-Fakahany EE; Doležal V
    Br J Pharmacol; 2011 Mar; 162(5):1029-44. PubMed ID: 20958290
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single- and double-knockout mice.
    Gautam D; Heard TS; Cui Y; Miller G; Bloodworth L; Wess J
    Mol Pharmacol; 2004 Aug; 66(2):260-7. PubMed ID: 15266016
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FRET-based sensors for the human M1-, M3-, and M5-acetylcholine receptors.
    Ziegler N; Bätz J; Zabel U; Lohse MJ; Hoffmann C
    Bioorg Med Chem; 2011 Feb; 19(3):1048-54. PubMed ID: 20716489
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vivo demonstration of M3 muscarinic receptor subtype selectivity of darifenacin in mice.
    Yamada S; Maruyama S; Takagi Y; Uchida S; Oki T
    Life Sci; 2006 Dec; 80(2):127-32. PubMed ID: 16996089
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effects on [35S]GTPgammaS binding using muscarinic agonists and antagonists in the gerbil brain.
    Pilar-Cuéllar F; Paniagua MA; Mostany R; Pérez CC; Fernández-López A
    J Chem Neuroanat; 2005 Oct; 30(2-3):119-28. PubMed ID: 16095872
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Probing the molecular mechanism of interaction between 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the muscarinic M(1) receptor: direct pharmacological evidence that AC-42 is an allosteric agonist.
    Langmead CJ; Fry VA; Forbes IT; Branch CL; Christopoulos A; Wood MD; Herdon HJ
    Mol Pharmacol; 2006 Jan; 69(1):236-46. PubMed ID: 16207821
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M(2) and M(4) muscarinic receptors in rat brain.
    Machová E; Jakubík J; El-Fakahany EE; Dolezal V
    J Pharmacol Exp Ther; 2007 Jul; 322(1):316-23. PubMed ID: 17446301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The relationship between muscarinic receptor occupancy and adenylate cyclase inhibition in the rabbit myocardium.
    Ehlert FJ
    Mol Pharmacol; 1985 Nov; 28(5):410-21. PubMed ID: 4058422
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Application of competition kinetics to investigate rat brain muscarinic receptors.
    Schreiber G; Henis YI; Sokolovsky M
    Isr J Med Sci; 1987; 23(1-2):36-43. PubMed ID: 3570744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A simple method for estimation of agonist activity at receptor subtypes: comparison of native and cloned M3 muscarinic receptors in guinea pig ileum and transfected cells.
    Ehlert FJ; Griffin MT; Sawyer GW; Bailon R
    J Pharmacol Exp Ther; 1999 May; 289(2):981-92. PubMed ID: 10215678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.