BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 19498170)

  • 1. Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity.
    Subramaniam S; Sixt KM; Barrow R; Snyder SH
    Science; 2009 Jun; 324(5932):1327-30. PubMed ID: 19498170
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy.
    Carbo M; Brandi V; Pascarella G; Staid DS; Colotti G; Polticelli F; Ilari A; Morea V
    Int J Mol Med; 2019 Dec; 44(6):2223-2233. PubMed ID: 31638189
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of Rhes, Ras homolog enriched in striatum, in neurodegenerative processes.
    Harrison LM; Lahoste GJ
    Exp Cell Res; 2013 Sep; 319(15):2310-5. PubMed ID: 23583659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Huntington's disease is a disorder of the corpus striatum: focus on Rhes (Ras homologue enriched in the striatum).
    Subramaniam S; Snyder SH
    Neuropharmacology; 2011 Jun; 60(7-8):1187-92. PubMed ID: 21044641
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
    Swarnkar S; Chen Y; Pryor WM; Shahani N; Page DT; Subramaniam S
    Neurobiol Dis; 2015 Oct; 82():66-77. PubMed ID: 26048156
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SUMO modification of Huntingtin and Huntington's disease pathology.
    Steffan JS; Agrawal N; Pallos J; Rockabrand E; Trotman LC; Slepko N; Illes K; Lukacsovich T; Zhu YZ; Cattaneo E; Pandolfi PP; Thompson LM; Marsh JL
    Science; 2004 Apr; 304(5667):100-4. PubMed ID: 15064418
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Golgi protein ACBD3 mediates neurotoxicity associated with Huntington's disease.
    Sbodio JI; Paul BD; Machamer CE; Snyder SH
    Cell Rep; 2013 Sep; 4(5):890-7. PubMed ID: 24012756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Striatal Induction and Spread of the Huntington's Disease Protein: A Novel Rhes Route.
    Subramaniam S
    J Huntingtons Dis; 2022; 11(3):281-290. PubMed ID: 35871361
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rhes suppression enhances disease phenotypes in Huntington's disease mice.
    Lee JH; Sowada MJ; Boudreau RL; Aerts AM; Thedens DR; Nopoulos P; Davidson BL
    J Huntingtons Dis; 2014; 3(1):65-71. PubMed ID: 25062765
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.
    Khoshnan A; Ko J; Watkin EE; Paige LA; Reinhart PH; Patterson PH
    J Neurosci; 2004 Sep; 24(37):7999-8008. PubMed ID: 15371500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.
    Subramaniam S; Mealer RG; Sixt KM; Barrow RK; Usiello A; Snyder SH
    J Biol Chem; 2010 Jul; 285(27):20428-32. PubMed ID: 20424159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brain.
    Ramírez-Jarquín UN; Sharma M; Shahani N; Li Y; Boregowda S; Subramaniam S
    Sci Adv; 2022 Mar; 8(12):eabm3877. PubMed ID: 35319973
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I
    Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity.
    Li H; Li SH; Johnston H; Shelbourne PF; Li XJ
    Nat Genet; 2000 Aug; 25(4):385-9. PubMed ID: 10932179
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.
    Dunah AW; Jeong H; Griffin A; Kim YM; Standaert DG; Hersch SM; Mouradian MM; Young AB; Tanese N; Krainc D
    Science; 2002 Jun; 296(5576):2238-43. PubMed ID: 11988536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
    Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.
    Mealer RG; Murray AJ; Shahani N; Subramaniam S; Snyder SH
    J Biol Chem; 2014 Feb; 289(6):3547-54. PubMed ID: 24324270
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin.
    Lajoie P; Snapp EL
    J Cell Sci; 2011 Oct; 124(Pt 19):3332-43. PubMed ID: 21896647
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.
    Martín-Flores N; Romaní-Aumedes J; Rué L; Canal M; Sanders P; Straccia M; Allen ND; Alberch J; Canals JM; Pérez-Navarro E; Malagelada C
    Mol Neurobiol; 2016 Jul; 53(5):2857-2868. PubMed ID: 25876513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease.
    Paul BD; Sbodio JI; Xu R; Vandiver MS; Cha JY; Snowman AM; Snyder SH
    Nature; 2014 May; 509(7498):96-100. PubMed ID: 24670645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.