168 related articles for article (PubMed ID: 19501051)
1. hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome.
McPate MJ; Zhang H; Cordeiro JM; Dempsey CE; Witchel HJ; Hancox JC
Biochem Biophys Res Commun; 2009 Aug; 386(1):111-7. PubMed ID: 19501051
[TBL] [Abstract][Full Text] [Related]
2. Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform.
Du CY; El Harchi A; McPate MJ; Orchard CH; Hancox JC
Biochem Biophys Res Commun; 2011 Feb; 405(2):222-7. PubMed ID: 21219869
[TBL] [Abstract][Full Text] [Related]
3. hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels.
McNally BA; Pendon ZD; Trudeau MC
J Biol Chem; 2017 Dec; 292(52):21548-21557. PubMed ID: 29089383
[TBL] [Abstract][Full Text] [Related]
4. Fentanyl-Induced Block of hERG Channels Is Exacerbated by Hypoxia, Hypokalemia, Alkalosis, and the Presence of hERG1b.
Tschirhart JN; Zhang S
Mol Pharmacol; 2020 Oct; 98(4):508-517. PubMed ID: 32321735
[TBL] [Abstract][Full Text] [Related]
5. Comparative effects of the short QT N588K mutation at 37 degrees C on hERG K+ channel current during ventricular, Purkinje fibre and atrial action potentials: an action potential clamp study.
McPate MJ; Zhang H; Adeniran I; Cordeiro JM; Witchel HJ; Hancox JC
J Physiol Pharmacol; 2009 Mar; 60(1):23-41. PubMed ID: 19439805
[TBL] [Abstract][Full Text] [Related]
6. A stable cell line inducibly expressing hERG1a/1b heteromeric channels.
Ríos-Pérez EB; Liu F; Stevens-Sostre WA; Eichel CA; Silignavong J; Robertson GA
J Pharmacol Toxicol Methods; 2021; 110():107081. PubMed ID: 34058320
[TBL] [Abstract][Full Text] [Related]
7. The N588K-HERG K+ channel mutation in the 'short QT syndrome': mechanism of gain-in-function determined at 37 degrees C.
McPate MJ; Duncan RS; Milnes JT; Witchel HJ; Hancox JC
Biochem Biophys Res Commun; 2005 Aug; 334(2):441-9. PubMed ID: 16011830
[TBL] [Abstract][Full Text] [Related]
8. Pharmacology of the short QT syndrome N588K-hERG K+ channel mutation: differential impact on selected class I and class III antiarrhythmic drugs.
McPate MJ; Duncan RS; Hancox JC; Witchel HJ
Br J Pharmacol; 2008 Nov; 155(6):957-66. PubMed ID: 18724381
[TBL] [Abstract][Full Text] [Related]
9. Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart.
Robertson GA; Jones EM; Wang J
Novartis Found Symp; 2005; 266():4-15; discussion 15-8, 44-5. PubMed ID: 16050259
[TBL] [Abstract][Full Text] [Related]
10. Modulation of I(Kr) inactivation by mutation N588K in KCNH2: a link to arrhythmogenesis in short QT syndrome.
Cordeiro JM; Brugada R; Wu YS; Hong K; Dumaine R
Cardiovasc Res; 2005 Aug; 67(3):498-509. PubMed ID: 16039272
[TBL] [Abstract][Full Text] [Related]
11. Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study.
Perissinotti LL; De Biase PM; Guo J; Yang PC; Lee MC; Clancy CE; Duff HJ; Noskov SY
Front Physiol; 2018; 9():207. PubMed ID: 29706893
[TBL] [Abstract][Full Text] [Related]
12. Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current.
Jonsson MK; van der Heyden MA; van Veen TA
J Mol Cell Cardiol; 2012 Sep; 53(3):369-74. PubMed ID: 22742967
[TBL] [Abstract][Full Text] [Related]
13. hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome.
Trudeau MC; Leung LM; Roti ER; Robertson GA
J Gen Physiol; 2011 Dec; 138(6):581-92. PubMed ID: 22124116
[TBL] [Abstract][Full Text] [Related]
14. Action potential clamp and pharmacology of the variant 1 Short QT Syndrome T618I hERG K⁺ channel.
El Harchi A; Melgari D; Zhang YH; Zhang H; Hancox JC
PLoS One; 2012; 7(12):e52451. PubMed ID: 23300672
[TBL] [Abstract][Full Text] [Related]
15. Differential effects of the β-adrenoceptor blockers carvedilol and metoprolol on SQT1- and SQT2-mutant channels.
Bodi I; Franke G; Pantulu ND; Wu K; Perez-Feliz S; Bode C; Zehender M; zur Hausen A; Brunner M; Odening KE
J Cardiovasc Electrophysiol; 2013 Oct; 24(10):1163-71. PubMed ID: 23718892
[TBL] [Abstract][Full Text] [Related]
16. Isoform-specific dominant-negative effects associated with hERG1 G628S mutation in long QT syndrome.
Stump MR; Gong Q; Zhou Z
PLoS One; 2012; 7(8):e42552. PubMed ID: 22876326
[TBL] [Abstract][Full Text] [Related]
17. The N-linker region of hERG1a upregulates hERG1b potassium channels.
Johnson AA; Crawford TR; Trudeau MC
J Biol Chem; 2022 Sep; 298(9):102233. PubMed ID: 35798139
[TBL] [Abstract][Full Text] [Related]
18. Modulation of K
Sale H; Roy S; Warrier J; Thangathirupathy S; Vadari Y; Gopal SK; Krishnamurthy P; Ramarao M
Br J Pharmacol; 2017 Aug; 174(15):2484-2500. PubMed ID: 28500657
[TBL] [Abstract][Full Text] [Related]
19. Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.
Larsen AP; Olesen SP; Grunnet M; Jespersen T
Pflugers Arch; 2008 Sep; 456(6):1137-48. PubMed ID: 18504605
[TBL] [Abstract][Full Text] [Related]
20. A novel mutation in the KCNH2 gene associated with short QT syndrome.
Sun Y; Quan XQ; Fromme S; Cox RH; Zhang P; Zhang L; Guo D; Guo J; Patel C; Kowey PR; Yan GX
J Mol Cell Cardiol; 2011 Mar; 50(3):433-41. PubMed ID: 21130771
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
