BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 19501590)

  • 1. Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.
    Mueller MT; Hermann PC; Witthauer J; Rubio-Viqueira B; Leicht SF; Huber S; Ellwart JW; Mustafa M; Bartenstein P; D'Haese JG; Schoenberg MH; Berger F; Jauch KW; Hidalgo M; Heeschen C
    Gastroenterology; 2009 Sep; 137(3):1102-13. PubMed ID: 19501590
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions.
    Matsubara S; Ding Q; Miyazaki Y; Kuwahata T; Tsukasa K; Takao S
    Sci Rep; 2013 Nov; 3():3230. PubMed ID: 24231729
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclopamine reverts acquired chemoresistance and down-regulates cancer stem cell markers in pancreatic cancer cell lines.
    Yao J; An Y; Wie JS; Ji ZL; Lu ZP; Wu JL; Jiang KR; Chen P; Xu ZK; Miao Y
    Swiss Med Wkly; 2011; 141():w13208. PubMed ID: 21630164
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells.
    Zhang GN; Liang Y; Zhou LJ; Chen SP; Chen G; Zhang TP; Kang T; Zhao YP
    Cancer Lett; 2011 Dec; 313(2):137-44. PubMed ID: 22030254
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer.
    Zhang Y; Liu L; Fan P; Bauer N; Gladkich J; Ryschich E; Bazhin AV; Giese NA; Strobel O; Hackert T; Hinz U; Gross W; Fortunato F; Herr I
    Oncotarget; 2015 Apr; 6(12):9999-10015. PubMed ID: 25846752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance.
    Huang FT; Zhuan-Sun YX; Zhuang YY; Wei SL; Tang J; Chen WB; Zhang SN
    Int J Oncol; 2012 Nov; 41(5):1707-14. PubMed ID: 22923052
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.
    Feldmann G; Dhara S; Fendrich V; Bedja D; Beaty R; Mullendore M; Karikari C; Alvarez H; Iacobuzio-Donahue C; Jimeno A; Gabrielson KL; Matsui W; Maitra A
    Cancer Res; 2007 Mar; 67(5):2187-96. PubMed ID: 17332349
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A combination of DR5 agonistic monoclonal antibody with gemcitabine targets pancreatic cancer stem cells and results in long-term disease control in human pancreatic cancer model.
    Rajeshkumar NV; Rasheed ZA; García-García E; López-Ríos F; Fujiwara K; Matsui WH; Hidalgo M
    Mol Cancer Ther; 2010 Sep; 9(9):2582-92. PubMed ID: 20660600
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combination of hedgehog signaling blockage and chemotherapy leads to tumor reduction in pancreatic adenocarcinomas.
    Bahra M; Kamphues C; Boas-Knoop S; Lippert S; Esendik U; Schüller U; Hartmann W; Waha A; Neuhaus P; Heppner F; Pietsch T; Koch A
    Pancreas; 2012 Mar; 41(2):222-9. PubMed ID: 22076568
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exosomes derived from cancer stem cells of gemcitabine-resistant pancreatic cancer cells enhance drug resistance by delivering miR-210.
    Yang Z; Zhao N; Cui J; Wu H; Xiong J; Peng T
    Cell Oncol (Dordr); 2020 Feb; 43(1):123-136. PubMed ID: 31713003
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Finding and killing the CRABs of pancreatic cancer.
    Caldwell ME; Tuveson DA
    Gastroenterology; 2009 Sep; 137(3):782-5. PubMed ID: 19643193
    [No Abstract]   [Full Text] [Related]  

  • 12. Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.
    Miyazaki Y; Matsubara S; Ding Q; Tsukasa K; Yoshimitsu M; Kosai K; Takao S
    Mol Cancer; 2016 Jun; 15(1):49. PubMed ID: 27349387
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling.
    Balic A; Sørensen MD; Trabulo SM; Sainz B; Cioffi M; Vieira CR; Miranda-Lorenzo I; Hidalgo M; Kleeff J; Erkan M; Heeschen C
    Mol Cancer Ther; 2014 Jul; 13(7):1758-71. PubMed ID: 24785258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells.
    Du Z; Qin R; Wei C; Wang M; Shi C; Tian R; Peng C
    Dig Dis Sci; 2011 Mar; 56(3):741-50. PubMed ID: 20683663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Highly lymphatic metastatic pancreatic cancer cells possess stem cell-like properties.
    Luo G; Long J; Cui X; Xiao Z; Liu Z; Shi S; Liu L; Liu C; Xu J; Li M; Yu X
    Int J Oncol; 2013 Mar; 42(3):979-84. PubMed ID: 23338123
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine.
    Hayashi T; Ding Q; Kuwahata T; Maeda K; Miyazaki Y; Matsubara S; Obara T; Natsugoe S; Takao S
    Cancer Sci; 2012 May; 103(5):889-96. PubMed ID: 22320450
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling.
    Chai X; Chu H; Yang X; Meng Y; Shi P; Gou S
    Sci Rep; 2015 Sep; 5():14404. PubMed ID: 26391180
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal.
    Rodova M; Fu J; Watkins DN; Srivastava RK; Shankar S
    PLoS One; 2012; 7(9):e46083. PubMed ID: 23029396
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
    Lonardo E; Hermann PC; Mueller MT; Huber S; Balic A; Miranda-Lorenzo I; Zagorac S; Alcala S; Rodriguez-Arabaolaza I; Ramirez JC; Torres-Ruíz R; Garcia E; Hidalgo M; Cebrián DÁ; Heuchel R; Löhr M; Berger F; Bartenstein P; Aicher A; Heeschen C
    Cell Stem Cell; 2011 Nov; 9(5):433-46. PubMed ID: 22056140
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of pancreatic cancer stem cell characteristics by α-Mangostin: Molecular mechanisms involving Sonic hedgehog and Nanog.
    Ma Y; Yu W; Shrivastava A; Srivastava RK; Shankar S
    J Cell Mol Med; 2019 Apr; 23(4):2719-2730. PubMed ID: 30712329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.