88 related articles for article (PubMed ID: 19504532)
1. Characterization of new PPARgamma agonists: benzimidazole derivatives - the importance of position 2.
Goebel M; Staels B; Unger T; Kintscher U; Gust R
ChemMedChem; 2009 Jul; 4(7):1136-42. PubMed ID: 19504532
[TBL] [Abstract][Full Text] [Related]
2. Characterization of new PPARgamma agonists: benzimidazole derivatives-importance of positions 5 and 6, and computational studies on the binding mode.
Goebel M; Wolber G; Markt P; Staels B; Unger T; Kintscher U; Gust R
Bioorg Med Chem; 2010 Aug; 18(16):5885-95. PubMed ID: 20656494
[TBL] [Abstract][Full Text] [Related]
3. Characterization of new PPARgamma agonists: analysis of telmisartan's structural components.
Goebel M; Clemenz M; Staels B; Unger T; Kintscher U; Gust R
ChemMedChem; 2009 Mar; 4(3):445-56. PubMed ID: 19197922
[TBL] [Abstract][Full Text] [Related]
4. Characterization of telmisartan-derived PPARγ agonists: importance of moiety shift from position 6 to 5 on potency, efficacy and cofactor recruitment.
Herbst L; Goebel M; Bandholtz S; Gust R; Kintscher U
ChemMedChem; 2012 Nov; 7(11):1935-42. PubMed ID: 24155042
[TBL] [Abstract][Full Text] [Related]
5. New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile.
Obermoser V; Urban ME; Murgueitio MS; Wolber G; Kintscher U; Gust R
Eur J Med Chem; 2016 Nov; 124():138-152. PubMed ID: 27569195
[TBL] [Abstract][Full Text] [Related]
6. Importance of 5/6-aryl substitution on the pharmacological profile of 4'-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid derived PPARγ agonists.
Obermoser V; Mauersberger R; Schuster D; Czifersky M; Lipova M; Siegl M; Kintscher U; Gust R
Eur J Med Chem; 2017 Jan; 126():590-603. PubMed ID: 27918994
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity.
Hieke M; Ness J; Steri R; Dittrich M; Greiner C; Werz O; Baumann K; Schubert-Zsilavecz M; Weggen S; Zettl H
J Med Chem; 2010 Jun; 53(12):4691-700. PubMed ID: 20503989
[TBL] [Abstract][Full Text] [Related]
8. Structural basis for telmisartan-mediated partial activation of PPAR gamma.
Amano Y; Yamaguchi T; Ohno K; Niimi T; Orita M; Sakashita H; Takeuchi M
Hypertens Res; 2012 Jul; 35(7):715-9. PubMed ID: 22357520
[TBL] [Abstract][Full Text] [Related]
9. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
Tapia I; Alonso-Cires L; López-Tudanca PL; Mosquera R; Labeaga L; Innerárity A; Orjales A
J Med Chem; 1999 Jul; 42(15):2870-80. PubMed ID: 10425096
[TBL] [Abstract][Full Text] [Related]
10. Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor γ (PPARγ) modulators.
Liu W; Lau F; Liu K; Wood HB; Zhou G; Chen Y; Li Y; Akiyama TE; Castriota G; Einstein M; Wang C; McCann ME; Doebber TW; Wu M; Chang CH; McNamara L; McKeever B; Mosley RT; Berger JP; Meinke PT
J Med Chem; 2011 Dec; 54(24):8541-54. PubMed ID: 22070604
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and Characterization of Telmisartan-Derived Cell Death Modulators to Circumvent Imatinib Resistance in Chronic Myeloid Leukemia.
Schoepf AM; Salcher S; Hohn V; Veider F; Obexer P; Gust R
ChemMedChem; 2020 Jun; 15(12):1067-1077. PubMed ID: 32298535
[TBL] [Abstract][Full Text] [Related]
12. Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.
Yuen CY; Wong WT; Tian XY; Wong SL; Lau CW; Yu J; Tomlinson B; Yao X; Huang Y
Cardiovasc Res; 2011 Apr; 90(1):122-9. PubMed ID: 21156825
[TBL] [Abstract][Full Text] [Related]
13. Rhodanine derivatives as novel peroxisome proliferator-activated receptor gamma agonists.
Liu Q; Zhang YY; Lu HL; Li QY; Zhou CH; Wang MW
Acta Pharmacol Sin; 2007 Dec; 28(12):2033-9. PubMed ID: 18031620
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome.
Mizuno CS; Chittiboyina AG; Shah FH; Patny A; Kurtz TW; Pershadsingh HA; Speth RC; Karamyan VT; Carvalho PB; Avery MA
J Med Chem; 2010 Feb; 53(3):1076-85. PubMed ID: 20073471
[TBL] [Abstract][Full Text] [Related]
15. Relaxant activity of 2-(substituted phenyl)-1H-benzimidazoles on isolated rat aortic rings: design and synthesis of 5-nitro derivatives.
Estrada-Soto S; Villalobos-Molina R; Aguirre-Crespo F; Vergara-Galicia J; Moreno-Díaz H; Torres-Piedra M; Navarrete-Vázquez G
Life Sci; 2006 Jun; 79(5):430-5. PubMed ID: 16487544
[TBL] [Abstract][Full Text] [Related]
16. Anti-adipogenic diarylheptanoids from Alnus hirsuta f. sibirica on 3T3-L1 cells.
Lee M; Song JY; Chin YW; Sung SH
Bioorg Med Chem Lett; 2013 Apr; 23(7):2069-73. PubMed ID: 23465614
[TBL] [Abstract][Full Text] [Related]
17. Analgesic and antispasmodic activities of 2-(2-nitro-phenyl)-1H-benzimidazole 5-carboxylic acid: evidence for the importance of the 2-(o-substituted phenyl) group.
Aydin S; Beis R; Can OD
Pharmazie; 2003 Jun; 58(6):405-8. PubMed ID: 12857004
[TBL] [Abstract][Full Text] [Related]
18. Telmisartan increases localization of glucose transporter 4 to the plasma membrane and increases glucose uptake via peroxisome proliferator-activated receptor γ in 3T3-L1 adipocytes.
Furukawa H; Mawatari K; Koyama K; Yasui S; Morizumi R; Shimohata T; Harada N; Takahashi A; Nakaya Y
Eur J Pharmacol; 2011 Jun; 660(2-3):485-91. PubMed ID: 21514293
[TBL] [Abstract][Full Text] [Related]
19. Novel Danshen methoxybenzo[b]furan derivative antagonizing adipogenic differentiation and production of inflammatory adipokines.
Sung HY; Jun JG; Kang SW; Kim HS; Shin D; Kang IJ; Kang YH
Chem Biol Interact; 2010 Dec; 188(3):457-66. PubMed ID: 20863820
[TBL] [Abstract][Full Text] [Related]
20. N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 2. Structure-activity relationship and optimization of the phenyl alkyl ether moiety.
Collins JL; Blanchard SG; Boswell GE; Charifson PS; Cobb JE; Henke BR; Hull-Ryde EA; Kazmierski WM; Lake DH; Leesnitzer LM; Lehmann J; Lenhard JM; Orband-Miller LA; Gray-Nunez Y; Parks DJ; Plunkett KD; Tong WQ
J Med Chem; 1998 Dec; 41(25):5037-54. PubMed ID: 9836621
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]