337 related articles for article (PubMed ID: 19506019)
1. Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation.
Halawani D; LeBlanc AC; Rouiller I; Michnick SW; Servant MJ; Latterich M
Mol Cell Biol; 2009 Aug; 29(16):4484-94. PubMed ID: 19506019
[TBL] [Abstract][Full Text] [Related]
2. The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP.
Niwa H; Ewens CA; Tsang C; Yeung HO; Zhang X; Freemont PS
J Biol Chem; 2012 Mar; 287(11):8561-70. PubMed ID: 22270372
[TBL] [Abstract][Full Text] [Related]
3. D1 ring is stable and nucleotide-independent, whereas D2 ring undergoes major conformational changes during the ATPase cycle of p97-VCP.
Wang Q; Song C; Yang X; Li CC
J Biol Chem; 2003 Aug; 278(35):32784-93. PubMed ID: 12807884
[TBL] [Abstract][Full Text] [Related]
4. Cryo-EM of the pathogenic VCP variant R155P reveals long-range conformational changes in the D2 ATPase ring.
Mountassif D; Fabre L; Zaid Y; Halawani D; Rouiller I
Biochem Biophys Res Commun; 2015 Dec; 468(4):636-41. PubMed ID: 26549226
[TBL] [Abstract][Full Text] [Related]
5. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.
Tresse E; Salomons FA; Vesa J; Bott LC; Kimonis V; Yao TP; Dantuma NP; Taylor JP
Autophagy; 2010 Feb; 6(2):217-27. PubMed ID: 20104022
[TBL] [Abstract][Full Text] [Related]
6. Multifunctional roles of the conserved Arg residues in the second region of homology of p97/valosin-containing protein.
Wang Q; Song C; Irizarry L; Dai R; Zhang X; Li CC
J Biol Chem; 2005 Dec; 280(49):40515-23. PubMed ID: 16216872
[TBL] [Abstract][Full Text] [Related]
7. Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
Custer SK; Neumann M; Lu H; Wright AC; Taylor JP
Hum Mol Genet; 2010 May; 19(9):1741-55. PubMed ID: 20147319
[TBL] [Abstract][Full Text] [Related]
8. Altered cofactor regulation with disease-associated p97/VCP mutations.
Zhang X; Gui L; Zhang X; Bulfer SL; Sanghez V; Wong DE; Lee Y; Lehmann L; Lee JS; Shih PY; Lin HJ; Iacovino M; Weihl CC; Arkin MR; Wang Y; Chou TF
Proc Natl Acad Sci U S A; 2015 Apr; 112(14):E1705-14. PubMed ID: 25775548
[TBL] [Abstract][Full Text] [Related]
9. A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.
Erzurumlu Y; Kose FA; Gozen O; Gozuacik D; Toth EA; Ballar P
Int J Biochem Cell Biol; 2013 Apr; 45(4):773-82. PubMed ID: 23333620
[TBL] [Abstract][Full Text] [Related]
10. Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.
Weihl CC; Miller SE; Hanson PI; Pestronk A
Hum Mol Genet; 2007 Apr; 16(8):919-28. PubMed ID: 17329348
[TBL] [Abstract][Full Text] [Related]
11. COP9 signalosome interacts ATP-dependently with p97/valosin-containing protein (VCP) and controls the ubiquitination status of proteins bound to p97/VCP.
Cayli S; Klug J; Chapiro J; Fröhlich S; Krasteva G; Orel L; Meinhardt A
J Biol Chem; 2009 Dec; 284(50):34944-53. PubMed ID: 19826004
[TBL] [Abstract][Full Text] [Related]
12. Altered intersubunit communication is the molecular basis for functional defects of pathogenic p97 mutants.
Tang WK; Xia D
J Biol Chem; 2013 Dec; 288(51):36624-35. PubMed ID: 24196964
[TBL] [Abstract][Full Text] [Related]
13. Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.
Weihl CC; Dalal S; Pestronk A; Hanson PI
Hum Mol Genet; 2006 Jan; 15(2):189-99. PubMed ID: 16321991
[TBL] [Abstract][Full Text] [Related]
14. Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy.
Ju JS; Weihl CC
Hum Mol Genet; 2010 Apr; 19(R1):R38-45. PubMed ID: 20410287
[TBL] [Abstract][Full Text] [Related]
15. Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.
Blythe EE; Olson KC; Chau V; Deshaies RJ
Proc Natl Acad Sci U S A; 2017 May; 114(22):E4380-E4388. PubMed ID: 28512218
[TBL] [Abstract][Full Text] [Related]
16. Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities.
Wang Q; Song C; Li CC
Biochem Biophys Res Commun; 2003 Jan; 300(2):253-60. PubMed ID: 12504076
[TBL] [Abstract][Full Text] [Related]
17. Valosin-containing protein (VCP) is a novel IQ motif-containing GTPase activating protein 1 (IQGAP1)-interacting protein.
Itoh N; Nagai T; Watanabe T; Taki K; Nabeshima T; Kaibuchi K; Yamada K
Biochem Biophys Res Commun; 2017 Dec; 493(4):1384-1389. PubMed ID: 28970065
[TBL] [Abstract][Full Text] [Related]
18. Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains.
Chou TF; Bulfer SL; Weihl CC; Li K; Lis LG; Walters MA; Schoenen FJ; Lin HJ; Deshaies RJ; Arkin MR
J Mol Biol; 2014 Jul; 426(15):2886-99. PubMed ID: 24878061
[TBL] [Abstract][Full Text] [Related]
19. Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region.
Song C; Wang Q; Song C; Lockett SJ; Colburn NH; Li CC; Wang JM; Rogers TJ
Biochim Biophys Acta; 2015 Jan; 1853(1):222-32. PubMed ID: 25447673
[TBL] [Abstract][Full Text] [Related]
20. Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells.
Kobayashi T; Tanaka K; Inoue K; Kakizuka A
J Biol Chem; 2002 Dec; 277(49):47358-65. PubMed ID: 12351637
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]