BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 19508886)

  • 21. Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.
    Tang SC; Nguyen LN; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Int J Cancer; 2014 Mar; 134(6):1484-94. PubMed ID: 24037730
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Interactions between Maraviroc and the ABCB1, ABCG2, and ABCC2 Transporters: An Important Role in Transplacental Pharmacokinetics.
    Tupova L; Ceckova M; Ambrus C; Sorf A; Ptackova Z; Gaborik Z; Staud F
    Drug Metab Dispos; 2019 Sep; 47(9):954-960. PubMed ID: 31266750
    [TBL] [Abstract][Full Text] [Related]  

  • 23. P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib.
    Tang SC; Lankheet NA; Poller B; Wagenaar E; Beijnen JH; Schinkel AH
    J Pharmacol Exp Ther; 2012 Apr; 341(1):164-73. PubMed ID: 22238213
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption.
    Uhr M; Steckler T; Yassouridis A; Holsboer F
    Neuropsychopharmacology; 2000 Apr; 22(4):380-7. PubMed ID: 10700657
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The role of the efflux carriers Abcg2 and Abcc2 for the hepatobiliary elimination of benzo[a]pyrene and its metabolites in mice.
    Kranz J; Hessel S; Aretz J; Seidel A; Petzinger E; Geyer J; Lampen A
    Chem Biol Interact; 2014 Dec; 224():36-41. PubMed ID: 25451572
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration.
    Vautier S; Milane A; Fernandez C; Chacun H; Lacomblez L; Farinotti R
    J Pharm Pharm Sci; 2009; 12(2):199-208. PubMed ID: 19732497
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Oral availability and brain penetration of the B-RAFV600E inhibitor vemurafenib can be enhanced by the P-GLYCOprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar.
    Durmus S; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
    Mol Pharm; 2012 Nov; 9(11):3236-45. PubMed ID: 23020847
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis.
    Cotte S; von Ahsen N; Kruse N; Huber B; Winkelmann A; Zettl UK; Starck M; König N; Tellez N; Dörr J; Paul F; Zipp F; Lühder F; Koepsell H; Pannek H; Montalban X; Gold R; Chan A
    Brain; 2009 Sep; 132(Pt 9):2517-30. PubMed ID: 19605531
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
    Yu XY; Lin SG; Chen X; Zhou ZW; Liang J; Duan W; Chowbay B; Wen JY; Chan E; Cao J; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):365-78. PubMed ID: 17504224
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.
    Vlaming ML; van Esch A; Pala Z; Wagenaar E; van de Wetering K; van Tellingen O; Schinkel AH
    Mol Cancer Ther; 2009 Dec; 8(12):3350-9. PubMed ID: 19996279
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout mouse models.
    Tiwari AK; Zhang R; Gallo JM
    Mol Cancer Ther; 2013 Jul; 12(7):1343-55. PubMed ID: 23635651
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance.
    Shi Z; Peng XX; Kim IW; Shukla S; Si QS; Robey RW; Bates SE; Shen T; Ashby CR; Fu LW; Ambudkar SV; Chen ZS
    Cancer Res; 2007 Nov; 67(22):11012-20. PubMed ID: 18006847
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Multidrug resistance phosphoglycoprotein (ABCB1) in the mouse placenta: fetal protection.
    Kalabis GM; Kostaki A; Andrews MH; Petropoulos S; Gibb W; Matthews SG
    Biol Reprod; 2005 Oct; 73(4):591-7. PubMed ID: 15917342
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the blood-brain barrier without restriction by ABCB1 and ABCG2.
    Lin F; Buil L; Sherris D; Beijnen JH; van Tellingen O
    Int J Cancer; 2013 Sep; 133(5):1222-33. PubMed ID: 23436212
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.
    de Waart DR; Vlaming ML; Kunne C; Schinkel AH; Oude Elferink RP
    Drug Metab Dispos; 2009 Aug; 37(8):1698-702. PubMed ID: 19443695
    [TBL] [Abstract][Full Text] [Related]  

  • 36. ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier.
    Do TM; Noel-Hudson MS; Ribes S; Besengez C; Smirnova M; Cisternino S; Buyse M; Calon F; Chimini G; Chacun H; Scherrmann JM; Farinotti R; Bourasset F
    J Alzheimers Dis; 2012; 30(1):155-66. PubMed ID: 22391220
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk.
    Campa D; Butterbach K; Slager SL; Skibola CF; de Sanjosé S; Benavente Y; Becker N; Foretova L; Maynadie M; Cocco P; Staines A; Kaaks R; Boffetta P; Brennan P; Conde L; Bracci PM; Caporaso NE; Strom SS; Camp NJ; Cerhan JR; ; Canzian F; Nieters A
    Int J Cancer; 2012 Aug; 131(4):803-12. PubMed ID: 21918980
    [TBL] [Abstract][Full Text] [Related]  

  • 38. P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice.
    Wang J; Gan C; Retmana IA; Sparidans RW; Li W; Lebre MC; Beijnen JH; Schinkel AH
    Int J Pharm; 2019 Feb; 556():172-180. PubMed ID: 30553002
    [TBL] [Abstract][Full Text] [Related]  

  • 39. P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice.
    Wang J; Gan C; Sparidans RW; Wagenaar E; van Hoppe S; Beijnen JH; Schinkel AH
    Pharmacol Res; 2018 Mar; 129():414-423. PubMed ID: 29155017
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.
    van Waterschoot RA; ter Heine R; Wagenaar E; van der Kruijssen CM; Rooswinkel RW; Huitema AD; Beijnen JH; Schinkel AH
    Br J Pharmacol; 2010 Jul; 160(5):1224-33. PubMed ID: 20590614
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.