185 related articles for article (PubMed ID: 19509419)
1. Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase.
Tchesnokov EP; Obikhod A; Massud I; Lisco A; Vanpouille C; Brichacek B; Balzarini J; McGuigan C; Derudas M; Margolis L; Schinazi RF; Götte M
J Biol Chem; 2009 Aug; 284(32):21496-504. PubMed ID: 19509419
[TBL] [Abstract][Full Text] [Related]
2. Thymidine analogue resistance suppression by V75I of HIV-1 reverse transcriptase: effects of substituting valine 75 on stavudine excision and discrimination.
Matamoros T; Nevot M; Martínez MA; Menéndez-Arias L
J Biol Chem; 2009 Nov; 284(47):32792-802. PubMed ID: 19801659
[TBL] [Abstract][Full Text] [Related]
3. The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation.
McMahon MA; Siliciano JD; Lai J; Liu JO; Stivers JT; Siliciano RF; Kohli RM
J Biol Chem; 2008 Nov; 283(46):31289-93. PubMed ID: 18818198
[TBL] [Abstract][Full Text] [Related]
4. Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase.
Tchesnokov EP; Obikhod A; Schinazi RF; Götte M
J Biol Chem; 2008 Dec; 283(49):34218-28. PubMed ID: 18940786
[TBL] [Abstract][Full Text] [Related]
5. Molecular mechanism of HIV-1 resistance to 3'-azido-2',3'-dideoxyguanosine.
Meteer JD; Schinazi RF; Mellors JW; Sluis-Cremer N
Antiviral Res; 2014 Jan; 101():62-7. PubMed ID: 24211331
[TBL] [Abstract][Full Text] [Related]
6. Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.
Vanpouille C; Lisco A; Introini A; Grivel JC; Munawwar A; Merbah M; Schinazi RF; Derudas M; McGuigan C; Balzarini J; Margolis L
Antimicrob Agents Chemother; 2012 May; 56(5):2604-11. PubMed ID: 22314523
[TBL] [Abstract][Full Text] [Related]
7. Sensitivity of V75I HIV-1 reverse transcriptase mutant selected in vitro by acyclovir to anti-HIV drugs.
McMahon MA; Siliciano JD; Kohli RM; Siliciano RF
AIDS; 2010 Jan; 24(2):319-23. PubMed ID: 20009920
[TBL] [Abstract][Full Text] [Related]
8. Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance.
Bertoletti N; Chan AH; Schinazi RF; Anderson KS
Molecules; 2020 Oct; 25(20):. PubMed ID: 33096918
[TBL] [Abstract][Full Text] [Related]
9. Amino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway.
Álvarez M; Nevot M; Mendieta J; Martínez MA; Menéndez-Arias L
J Biol Chem; 2018 Feb; 293(7):2247-2259. PubMed ID: 29275329
[TBL] [Abstract][Full Text] [Related]
10. Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.
Lisco A; Vanpouille C; Tchesnokov EP; Grivel JC; Biancotto A; Brichacek B; Elliott J; Fromentin E; Shattock R; Anton P; Gorelick R; Balzarini J; McGuigan C; Derudas M; Götte M; Schinazi RF; Margolis L
Cell Host Microbe; 2008 Sep; 4(3):260-270. PubMed ID: 18779052
[TBL] [Abstract][Full Text] [Related]
11. Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine.
Feng JY; Myrick FT; Margot NA; Mulamba GB; Rimsky L; Borroto-Esoda K; Selmi B; Canard B
Nucleosides Nucleotides Nucleic Acids; 2006; 25(1):89-107. PubMed ID: 16440988
[TBL] [Abstract][Full Text] [Related]
12. Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
Sluis-Cremer N; Sheen CW; Zelina S; Torres PS; Parikh UM; Mellors JW
Antimicrob Agents Chemother; 2007 Jan; 51(1):48-53. PubMed ID: 17088490
[TBL] [Abstract][Full Text] [Related]
13. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
14. The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.
Isel C; Ehresmann C; Walter P; Ehresmann B; Marquet R
J Biol Chem; 2001 Dec; 276(52):48725-32. PubMed ID: 11668180
[TBL] [Abstract][Full Text] [Related]
15. Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.
White KL; Chen JM; Margot NA; Wrin T; Petropoulos CJ; Naeger LK; Swaminathan S; Miller MD
Antimicrob Agents Chemother; 2004 Mar; 48(3):992-1003. PubMed ID: 14982794
[TBL] [Abstract][Full Text] [Related]
16. Biochemical studies on the mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to 1-(beta-D-dioxolane)thymine triphosphate.
Lennerstrand J; Chu CK; Schinazi RF
Antimicrob Agents Chemother; 2007 Jun; 51(6):2078-84. PubMed ID: 17403997
[TBL] [Abstract][Full Text] [Related]
17. Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase.
Frankel FA; Marchand B; Turner D; Götte M; Wainberg MA
Antimicrob Agents Chemother; 2005 Jul; 49(7):2657-64. PubMed ID: 15980333
[TBL] [Abstract][Full Text] [Related]
18. The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.
Miranda LR; Götte M; Liang F; Kuritzkes DR
Antimicrob Agents Chemother; 2005 Jul; 49(7):2648-56. PubMed ID: 15980332
[TBL] [Abstract][Full Text] [Related]
19. Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure.
Miller V; Larder BA
Antivir Ther; 2001; 6 Suppl 3():25-44. PubMed ID: 11678471
[TBL] [Abstract][Full Text] [Related]
20. Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC.
Girouard M; Diallo K; Marchand B; McCormick S; Götte M
J Biol Chem; 2003 Sep; 278(36):34403-10. PubMed ID: 12819190
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]