BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 19519523)

  • 1. A unique mechanism of chaperone action: heme regulation of Hap1 activity involves separate control of repression and activation.
    Lee HC; Zhang L
    Protein Pept Lett; 2009; 16(6):642-9. PubMed ID: 19519523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel mode of chaperone action: heme activation of Hap1 by enhanced association of Hsp90 with the repressed Hsp70-Hap1 complex.
    Lan C; Lee HC; Tang S; Zhang L
    J Biol Chem; 2004 Jun; 279(26):27607-12. PubMed ID: 15102838
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Hsp70-Ydj1 molecular chaperone represses the activity of the heme activator protein Hap1 in the absence of heme.
    Hon T; Lee HC; Hach A; Johnson JL; Craig EA; Erdjument-Bromage H; Tempst P; Zhang L
    Mol Cell Biol; 2001 Dec; 21(23):7923-32. PubMed ID: 11689685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heme levels switch the function of Hap1 of Saccharomyces cerevisiae between transcriptional activator and transcriptional repressor.
    Hickman MJ; Winston F
    Mol Cell Biol; 2007 Nov; 27(21):7414-24. PubMed ID: 17785431
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The heme activator protein Hap1 represses transcription by a heme-independent mechanism in Saccharomyces cerevisiae.
    Hon T; Lee HC; Hu Z; Iyer VR; Zhang L
    Genetics; 2005 Mar; 169(3):1343-52. PubMed ID: 15654089
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The molecular chaperone Hsp90 mediates heme activation of the yeast transcriptional activator Hap1.
    Lee HC; Hon T; Zhang L
    J Biol Chem; 2002 Mar; 277(9):7430-7. PubMed ID: 11751848
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The yeast heme-responsive transcriptional activator Hap1 is a preexisting dimer in the absence of heme.
    Hon T; Hach A; Tamalis D; Zhu Y; Zhang L
    J Biol Chem; 1999 Aug; 274(32):22770-4. PubMed ID: 10428861
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hsp90/Hsp70 chaperone machine regulation of the Saccharomyces MAL-activator as determined in vivo using noninducible and constitutive mutant alleles.
    Ran F; Bali M; Michels CA
    Genetics; 2008 May; 179(1):331-43. PubMed ID: 18458105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hsp110 chaperones control client fate determination in the hsp70-Hsp90 chaperone system.
    Mandal AK; Gibney PA; Nillegoda NB; Theodoraki MA; Caplan AJ; Morano KA
    Mol Biol Cell; 2010 May; 21(9):1439-48. PubMed ID: 20237159
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the HAP1 gene involves positive actions of histone deacetylases.
    Xin X; Lan C; Lee HC; Zhang L
    Biochem Biophys Res Commun; 2007 Oct; 362(1):120-125. PubMed ID: 17706600
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular mechanism governing heme signaling in yeast: a higher-order complex mediates heme regulation of the transcriptional activator HAP1.
    Zhang L; Hach A; Wang C
    Mol Cell Biol; 1998 Jul; 18(7):3819-28. PubMed ID: 9632766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors.
    Paul A; Garcia YA; Zierer B; Patwardhan C; Gutierrez O; Hildenbrand Z; Harris DC; Balsiger HA; Sivils JC; Johnson JL; Buchner J; Chadli A; Cox MB
    J Biol Chem; 2014 May; 289(22):15297-308. PubMed ID: 24753260
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Functional and physical interaction between yeast Hsp90 and Hsp70.
    Kravats AN; Hoskins JR; Reidy M; Johnson JL; Doyle SM; Genest O; Masison DC; Wickner S
    Proc Natl Acad Sci U S A; 2018 Mar; 115(10):E2210-E2219. PubMed ID: 29463764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Sch9 protein kinase regulates Hsp90 chaperone complex signal transduction activity in vivo.
    Morano KA; Thiele DJ
    EMBO J; 1999 Nov; 18(21):5953-62. PubMed ID: 10545107
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple domains mediate heme control of the yeast activator HAP1.
    Haldi ML; Guarente L
    Mol Gen Genet; 1995 Jul; 248(2):229-35. PubMed ID: 7651346
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system.
    Brychzy A; Rein T; Winklhofer KF; Hartl FU; Young JC; Obermann WM
    EMBO J; 2003 Jul; 22(14):3613-23. PubMed ID: 12853476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase.
    Truman AW; Kristjansdottir K; Wolfgeher D; Ricco N; Mayampurath A; Volchenboum SL; Clotet J; Kron SJ
    J Proteomics; 2015 Jan; 112():285-300. PubMed ID: 25452130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.
    SolĂ­s EJ; Pandey JP; Zheng X; Jin DX; Gupta PB; Airoldi EM; Pincus D; Denic V
    Mol Cell; 2016 Jul; 63(1):60-71. PubMed ID: 27320198
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase.
    Morishima Y; Lau M; Pratt WB; Osawa Y
    J Biol Chem; 2023 Feb; 299(2):102856. PubMed ID: 36596358
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural environment dictates the biological significance of heme-responsive motifs and the role of Hsp90 in the activation of the heme activator protein Hap1.
    Lee HC; Hon T; Lan C; Zhang L
    Mol Cell Biol; 2003 Aug; 23(16):5857-66. PubMed ID: 12897155
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.