These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

93 related articles for article (PubMed ID: 19519866)

  • 21. Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.
    Beckers A; Organe S; Timmermans L; Scheys K; Peeters A; Brusselmans K; Verhoeven G; Swinnen JV
    Cancer Res; 2007 Sep; 67(17):8180-7. PubMed ID: 17804731
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.
    Matsuzawa-Nagata N; Takamura T; Ando H; Nakamura S; Kurita S; Misu H; Ota T; Yokoyama M; Honda M; Miyamoto K; Kaneko S
    Metabolism; 2008 Aug; 57(8):1071-7. PubMed ID: 18640384
    [TBL] [Abstract][Full Text] [Related]  

  • 23. High-fat diet feeding impairs both the expression and activity of AMPKa in rats' skeletal muscle.
    Liu Y; Wan Q; Guan Q; Gao L; Zhao J
    Biochem Biophys Res Commun; 2006 Jan; 339(2):701-7. PubMed ID: 16316631
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Impairment of fat oxidation under high- vs. low-glycemic index diet occurs before the development of an obese phenotype.
    Isken F; Klaus S; Petzke KJ; Loddenkemper C; Pfeiffer AF; Weickert MO
    Am J Physiol Endocrinol Metab; 2010 Feb; 298(2):E287-95. PubMed ID: 19934403
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Expression and characterization of recombinant fungal acetyl-CoA carboxylase and isolation of a soraphen-binding domain.
    Weatherly SC; Volrath SL; Elich TD
    Biochem J; 2004 May; 380(Pt 1):105-10. PubMed ID: 14766011
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Four weeks high fat feeding induces insulin resistance without affecting dopamine release or gene expression patterns in the hypothalamus of C57Bl6 mice.
    de Leeuw van Weenen JE; Hu L; Jansen-Van Zelm K; de Vries MG; Tamsma JT; Romijn JA; Pijl H
    Brain Res; 2009 Jan; 1250():141-8. PubMed ID: 19028458
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
    Taylor A; Irwin N; McKillop AM; Flatt PR; Gault VA
    Biol Chem; 2008 Apr; 389(4):441-5. PubMed ID: 18225986
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Prevention of diet-induced obesity by dietary isomerized hop extract containing isohumulones, in rodents.
    Yajima H; Noguchi T; Ikeshima E; Shiraki M; Kanaya T; Tsuboyama-Kasaoka N; Ezaki O; Oikawa S; Kondo K
    Int J Obes (Lond); 2005 Aug; 29(8):991-7. PubMed ID: 15852044
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet.
    Hägerkvist R; Jansson L; Welsh N
    Clin Sci (Lond); 2008 Jan; 114(1):65-71. PubMed ID: 17868036
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.
    Savage DB; Choi CS; Samuel VT; Liu ZX; Zhang D; Wang A; Zhang XM; Cline GW; Yu XX; Geisler JG; Bhanot S; Monia BP; Shulman GI
    J Clin Invest; 2006 Mar; 116(3):817-24. PubMed ID: 16485039
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation.
    Keil S; Müller M; Zoller G; Haschke G; Schroeter K; Glien M; Ruf S; Focken I; Herling AW; Schmoll D
    J Med Chem; 2010 Dec; 53(24):8679-87. PubMed ID: 21082864
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.
    Harriman G; Greenwood J; Bhat S; Huang X; Wang R; Paul D; Tong L; Saha AK; Westlin WF; Kapeller R; Harwood HJ
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):E1796-805. PubMed ID: 26976583
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice.
    Oh W; Abu-Elheiga L; Kordari P; Gu Z; Shaikenov T; Chirala SS; Wakil SJ
    Proc Natl Acad Sci U S A; 2005 Feb; 102(5):1384-9. PubMed ID: 15677334
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A Novel Acetyl-CoA Carboxylase 2 Selective Inhibitor Improves Whole-Body Insulin Resistance and Hyperglycemia in Diabetic Mice through Target-Dependent Pathways.
    Takagi H; Tanimoto K; Shimazaki A; Tonomura Y; Momosaki S; Sakamoto S; Abe K; Notoya M; Yukioka H
    J Pharmacol Exp Ther; 2020 Mar; 372(3):256-263. PubMed ID: 31900320
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity.
    Choi CS; Savage DB; Abu-Elheiga L; Liu ZX; Kim S; Kulkarni A; Distefano A; Hwang YJ; Reznick RM; Codella R; Zhang D; Cline GW; Wakil SJ; Shulman GI
    Proc Natl Acad Sci U S A; 2007 Oct; 104(42):16480-5. PubMed ID: 17923673
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structure.
    Griffith DA; Dow RL; Huard K; Edmonds DJ; Bagley SW; Polivkova J; Zeng D; Garcia-Irizarry CN; Southers JA; Esler W; Amor P; Loomis K; McPherson K; Bahnck KB; Préville C; Banks T; Moore DE; Mathiowetz AM; Menhaji-Klotz E; Smith AC; Doran SD; Beebe DA; Dunn MF
    J Med Chem; 2013 Sep; 56(17):7110-9. PubMed ID: 23981033
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of the yeast ACC1 gene product (acetyl-CoA carboxylase) as the target of the polyketide fungicide soraphen A.
    Vahlensieck HF; Pridzun L; Reichenbach H; Hinnen A
    Curr Genet; 1994 Feb; 25(2):95-100. PubMed ID: 7916271
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
    Gross AS; Zimmermann A; Pendl T; Schroeder S; Schoenlechner H; Knittelfelder O; Lamplmayr L; Santiso A; Aufschnaiter A; Waltenstorfer D; Ortonobes Lara S; Stryeck S; Kast C; Ruckenstuhl C; Hofer SJ; Michelitsch B; Woelflingseder M; Müller R; Carmona-Gutierrez D; Madl T; Büttner S; Fröhlich KU; Shevchenko A; Eisenberg T
    J Biol Chem; 2019 Aug; 294(32):12020-12039. PubMed ID: 31209110
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.
    Corominas-Faja B; Cuyàs E; Gumuzio J; Bosch-Barrera J; Leis O; Martin ÁG; Menendez JA
    Oncotarget; 2014 Sep; 5(18):8306-16. PubMed ID: 25246709
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product.
    Shen Y; Volrath SL; Weatherly SC; Elich TD; Tong L
    Mol Cell; 2004 Dec; 16(6):881-91. PubMed ID: 15610732
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.