181 related articles for article (PubMed ID: 19525225)
21. The miR-1-NOTCH3-Asef pathway is important for colorectal tumor cell migration.
Furukawa S; Kawasaki Y; Miyamoto M; Hiyoshi M; Kitayama J; Akiyama T
PLoS One; 2013; 8(11):e80609. PubMed ID: 24244701
[TBL] [Abstract][Full Text] [Related]
22. Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.
Meng F; Meliton A; Moldobaeva N; Mutlu G; Kawasaki Y; Akiyama T; Birukova AA
Am J Physiol Lung Cell Mol Physiol; 2015 Mar; 308(5):L452-63. PubMed ID: 25539852
[TBL] [Abstract][Full Text] [Related]
23. Advances and Insights of APC-Asef Inhibitors for Metastatic Colorectal Cancer Therapy.
Yang X; Zhong J; Zhang Q; Feng L; Zheng Z; Zhang J; Lu S
Front Mol Biosci; 2021; 8():662579. PubMed ID: 33968990
[TBL] [Abstract][Full Text] [Related]
24. Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier.
Tian Y; Gawlak G; Shah AS; Higginbotham K; Tian X; Kawasaki Y; Akiyama T; Sacks DB; Birukova AA
J Biol Chem; 2015 Feb; 290(7):4097-109. PubMed ID: 25492863
[TBL] [Abstract][Full Text] [Related]
25. Design, synthesis and biological evaluation of 2-H pyrazole derivatives containing morpholine moieties as highly potent small molecule inhibitors of APC-Asef interaction.
Yan XQ; Wang ZC; Qi PF; Li G; Zhu HL
Eur J Med Chem; 2019 Sep; 177():425-447. PubMed ID: 31158755
[TBL] [Abstract][Full Text] [Related]
26. PH domain-mediated membrane targeting of Asef.
Muroya K; Kawasaki Y; Hayashi T; Ohwada S; Akiyama T
Biochem Biophys Res Commun; 2007 Mar; 355(1):85-8. PubMed ID: 17292853
[TBL] [Abstract][Full Text] [Related]
27. Htid-1, the human homolog of the Drosophila melanogaster l(2)tid tumor suppressor, defines a novel physiological role of APC.
Kurzik-Dumke U; Czaja J
Cell Signal; 2007 Sep; 19(9):1973-85. PubMed ID: 17588722
[TBL] [Abstract][Full Text] [Related]
28. Identification of a link between the tumour suppressor APC and the kinesin superfamily.
Jimbo T; Kawasaki Y; Koyama R; Sato R; Takada S; Haraguchi K; Akiyama T
Nat Cell Biol; 2002 Apr; 4(4):323-7. PubMed ID: 11912492
[TBL] [Abstract][Full Text] [Related]
29. Asef is a Cdc42-specific guanine nucleotide exchange factor.
Gotthardt K; Ahmadian MR
Biol Chem; 2007 Jan; 388(1):67-71. PubMed ID: 17214551
[TBL] [Abstract][Full Text] [Related]
30. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.
Prossomariti A; Piazzi G; D'Angelo L; Miccoli S; Turchetti D; Alquati C; Montagna C; Bazzoli F; Ricciardiello L
Mol Cancer Res; 2018 Dec; 16(12):1965-1976. PubMed ID: 30072583
[TBL] [Abstract][Full Text] [Related]
31. Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover.
Evans JC; Hines KM; Forsythe JG; Erdogan B; Shi M; Hill S; Rose KL; McLean JA; Webb DJ
J Proteome Res; 2014 Jul; 13(7):3303-13. PubMed ID: 24874604
[TBL] [Abstract][Full Text] [Related]
32. Conformational Selection Mechanism Provides Structural Insights into the Optimization of APC-Asef Inhibitors.
He X; Huang N; Qiu Y; Zhang J; Liu Y; Yin XL; Lu S
Molecules; 2021 Feb; 26(4):. PubMed ID: 33670371
[TBL] [Abstract][Full Text] [Related]
33. A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Phull MS; Jadav SS; Gundla R; Mainkar PS
Eur J Med Chem; 2021 Feb; 212():113149. PubMed ID: 33445154
[TBL] [Abstract][Full Text] [Related]
34. Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation.
Royal I; Lamarche-Vane N; Lamorte L; Kaibuchi K; Park M
Mol Biol Cell; 2000 May; 11(5):1709-25. PubMed ID: 10793146
[TBL] [Abstract][Full Text] [Related]
35. Phosphorylation of p85 beta PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth.
Shin EY; Shin KS; Lee CS; Woo KN; Quan SH; Soung NK; Kim YG; Cha CI; Kim SR; Park D; Bokoch GM; Kim EG
J Biol Chem; 2002 Nov; 277(46):44417-30. PubMed ID: 12226077
[TBL] [Abstract][Full Text] [Related]
36. The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.
Huang X; Langelotz C; Hetfeld-Pechoc BK; Schwenk W; Dubiel W
J Mol Biol; 2009 Aug; 391(4):691-702. PubMed ID: 19576224
[TBL] [Abstract][Full Text] [Related]
37. Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein.
Homma MK; Li D; Krebs EG; Yuasa Y; Homma Y
Proc Natl Acad Sci U S A; 2002 Apr; 99(9):5959-64. PubMed ID: 11972058
[TBL] [Abstract][Full Text] [Related]
38. Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signalling.
Brauburger K; Akyildiz S; Ruppert JG; Graeb M; Bernkopf DB; Hadjihannas MV; Behrens J
FEBS J; 2014 Feb; 281(3):787-801. PubMed ID: 24251807
[TBL] [Abstract][Full Text] [Related]
39. Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.
Näthke I
Nat Rev Cancer; 2006 Dec; 6(12):967-74. PubMed ID: 17093505
[TBL] [Abstract][Full Text] [Related]
40. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
Friedrich A; Kullmann F
Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
