142 related articles for article (PubMed ID: 19525443)
1. Hemangiosarcoma in rodents: mode-of-action evaluation and human relevance.
Cohen SM; Storer RD; Criswell KA; Doerrer NG; Dellarco VL; Pegg DG; Wojcinski ZW; Malarkey DE; Jacobs AC; Klaunig JE; Swenberg JA; Cook JC
Toxicol Sci; 2009 Sep; 111(1):4-18. PubMed ID: 19525443
[TBL] [Abstract][Full Text] [Related]
2. From the Cover: Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.
Cook JC; Obert LA; Koza-Taylor P; Coskran TM; Opsahl AC; Ziemek D; Roy M; Qian J; Lawton MP; Criswell KA
Toxicol Sci; 2018 Jan; 161(1):58-75. PubMed ID: 28973697
[TBL] [Abstract][Full Text] [Related]
3. Mode of action associated with development of hemangiosarcoma in mice given pregabalin and assessment of human relevance.
Criswell KA; Cook JC; Wojcinski Z; Pegg D; Herman J; Wesche D; Giddings J; Brady JT; Anderson T
Toxicol Sci; 2012 Jul; 128(1):57-71. PubMed ID: 22539620
[TBL] [Abstract][Full Text] [Related]
4. A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA Risk Assessment Guidelines.
Doull J; Cattley R; Elcombe C; Lake BG; Swenberg J; Wilkinson C; Williams G; van Gemert M
Regul Toxicol Pharmacol; 1999 Jun; 29(3):327-57. PubMed ID: 10388618
[TBL] [Abstract][Full Text] [Related]
5. Key components of the mode of action for hemangiosarcoma induction in pregabalin-treated mice: evidence of increased bicarbonate, dysregulated erythropoiesis, macrophage activation, and increased angiogenic growth factors in mice but not in rats.
Criswell KA; Wojcinski Z; Pegg D; Albassam M; Duddy S; Olsen E; Bailie M; Foote S; Anderson T
Toxicol Sci; 2012 Jul; 128(1):22-41. PubMed ID: 22539625
[TBL] [Abstract][Full Text] [Related]
6. Cancer risk assessment for 1,3-butadiene: data integration opportunities.
Preston RJ
Chem Biol Interact; 2007 Mar; 166(1-3):150-5. PubMed ID: 16647696
[TBL] [Abstract][Full Text] [Related]
7. Mode of action in relevance of rodent liver tumors to human cancer risk.
Holsapple MP; Pitot HC; Cohen SM; Boobis AR; Klaunig JE; Pastoor T; Dellarco VL; Dragan YP
Toxicol Sci; 2006 Jan; 89(1):51-6. PubMed ID: 16221960
[TBL] [Abstract][Full Text] [Related]
8. Rodent carcinogenicity of peroxisome proliferators and issues on human relevance.
Lai DY
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2004 May; 22(1):37-55. PubMed ID: 15845221
[TBL] [Abstract][Full Text] [Related]
9. Formaldehyde and glutaraldehyde and nasal cytotoxicity: case study within the context of the 2006 IPCS Human Framework for the Analysis of a cancer mode of action for humans.
McGregor D; Bolt H; Cogliano V; Richter-Reichhelm HB
Crit Rev Toxicol; 2006; 36(10):821-35. PubMed ID: 17118731
[TBL] [Abstract][Full Text] [Related]
10. Mode of action of butoxyethanol-induced mouse liver hemangiosarcomas and hepatocellular carcinomas.
Klaunig JE; Kamendulis LM
Toxicol Lett; 2005 Mar; 156(1):107-15. PubMed ID: 15705491
[TBL] [Abstract][Full Text] [Related]
11. Development of a quantitative model incorporating key events in a hepatotoxic mode of action to predict tumor incidence.
Luke NS; Sams R; DeVito MJ; Conolly RB; El-Masri HA
Toxicol Sci; 2010 May; 115(1):253-66. PubMed ID: 20106946
[TBL] [Abstract][Full Text] [Related]
12. Carcinogenic mode of action of folpet in mice and evaluation of its relevance to humans.
Cohen SM; Gordon EB; Singh P; Arce GT; Nyska A
Crit Rev Toxicol; 2010 Jul; 40(6):531-45. PubMed ID: 20521864
[TBL] [Abstract][Full Text] [Related]
13. Pregabalin induces hepatic hypoxia and increases endothelial cell proliferation in mice, a process inhibited by dietary vitamin E supplementation.
Criswell KA; Cook JC; Morse D; Lawton M; Somps C; Obert L; Roy M; Sokolowski S; Koza-Taylor P; Colangelo J; Navetta K; Brady J; Pegg D; Wojcinski Z; Rahbari R; Duddy S; Anderson T
Toxicol Sci; 2012 Jul; 128(1):42-56. PubMed ID: 22539613
[TBL] [Abstract][Full Text] [Related]
14. Kupffer cells participate in 2-butoxyethanol-induced liver hemangiosarcomas.
Kamendulis LM; Corthals SM; Klaunig JE
Toxicology; 2010 Apr; 270(2-3):131-6. PubMed ID: 20153399
[TBL] [Abstract][Full Text] [Related]
15. A mechanistic interpretation of the oncogenicity of chlorothalonil in rodents and an assessment of human relevance.
Wilkinson CF; Killeen JC
Regul Toxicol Pharmacol; 1996 Aug; 24(1 Pt 1):69-84. PubMed ID: 8921547
[TBL] [Abstract][Full Text] [Related]
16. An evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide.
McCarroll N; Keshava N; Cimino M; Chu M; Dearfield K; Keshava C; Kligerman A; Owen R; Protzel A; Putzrath R; Schoeny R
Environ Mol Mutagen; 2008 Mar; 49(2):117-31. PubMed ID: 18240158
[TBL] [Abstract][Full Text] [Related]
17. Mechanisms of 2-butoxyethanol-induced hemangiosarcomas.
Corthals SM; Kamendulis LM; Klaunig JE
Toxicol Sci; 2006 Aug; 92(2):378-86. PubMed ID: 16675516
[TBL] [Abstract][Full Text] [Related]
18. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
Walker VE; Walker DM; Meng Q; McDonald JD; Scott BR; Seilkop SK; Claffey DJ; Upton PB; Powley MW; Swenberg JA; Henderson RF;
Res Rep Health Eff Inst; 2009 Aug; (144):3-79. PubMed ID: 20017413
[TBL] [Abstract][Full Text] [Related]
19. Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment.
Proctor DM; Gatto NM; Hong SJ; Allamneni KP
Toxicol Sci; 2007 Aug; 98(2):313-26. PubMed ID: 17426108
[TBL] [Abstract][Full Text] [Related]
20. Mode-of-action analysis for induction of rat liver tumors by pyrethrins: relevance to human cancer risk.
Osimitz TG; Lake BG
Crit Rev Toxicol; 2009; 39(6):501-11. PubMed ID: 19463055
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]