These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. PGE synthase inhibitors as an alternative to COX-2 inhibitors. Jachak SM Curr Opin Investig Drugs; 2007 May; 8(5):411-5. PubMed ID: 17520870 [TBL] [Abstract][Full Text] [Related]
4. Inhibitors of the microsomal prostaglandin E(2) synthase-1 as alternative to non steroidal anti-inflammatory drugs (NSAIDs)--a critical review. Koeberle A; Werz O Curr Med Chem; 2009; 16(32):4274-96. PubMed ID: 19754418 [TBL] [Abstract][Full Text] [Related]
5. Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders. Koeberle A; Werz O Biochem Pharmacol; 2015 Nov; 98(1):1-15. PubMed ID: 26123522 [TBL] [Abstract][Full Text] [Related]
6. Characterization of microsomal prostaglandin E synthase 1 inhibitors. Korotkova M; Jakobsson PJ Basic Clin Pharmacol Toxicol; 2014 Jan; 114(1):64-9. PubMed ID: 24138533 [TBL] [Abstract][Full Text] [Related]
7. Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor. Mbalaviele G; Pauley AM; Shaffer AF; Zweifel BS; Mathialagan S; Mnich SJ; Nemirovskiy OV; Carter J; Gierse JK; Wang JL; Vazquez ML; Moore WM; Masferrer JL Biochem Pharmacol; 2010 May; 79(10):1445-54. PubMed ID: 20067770 [TBL] [Abstract][Full Text] [Related]
8. Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. Guerrero MD; Aquino M; Bruno I; Riccio R; Terencio MC; Payá M Eur J Pharmacol; 2009 Oct; 620(1-3):112-9. PubMed ID: 19686718 [TBL] [Abstract][Full Text] [Related]
9. Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro. Bruno A; Di Francesco L; Coletta I; Mangano G; Alisi MA; Polenzani L; Milanese C; Anzellotti P; Ricciotti E; Dovizio M; Di Francesco A; Tacconelli S; Capone ML; Patrignani P Biochem Pharmacol; 2010 Apr; 79(7):974-81. PubMed ID: 19925781 [TBL] [Abstract][Full Text] [Related]
10. Inhibitors of microsomal prostaglandin E2 synthase-1 enzyme as emerging anti-inflammatory candidates. Bahia MS; Katare YK; Silakari O; Vyas B; Silakari P Med Res Rev; 2014 Jul; 34(4):825-55. PubMed ID: 25019142 [TBL] [Abstract][Full Text] [Related]
12. Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation. Arhancet GB; Walker DP; Metz S; Fobian YM; Heasley SE; Carter JS; Springer JR; Jones DE; Hayes MJ; Shaffer AF; Jerome GM; Baratta MT; Zweifel B; Moore WM; Masferrer JL; Vazquez ML Bioorg Med Chem Lett; 2013 Feb; 23(4):1114-9. PubMed ID: 23260349 [TBL] [Abstract][Full Text] [Related]
13. Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E(2) synthase-1. Koeberle A; Haberl EM; Rossi A; Pergola C; Dehm F; Northoff H; Troschuetz R; Sautebin L; Werz O Bioorg Med Chem; 2009 Dec; 17(23):7924-32. PubMed ID: 19884011 [TBL] [Abstract][Full Text] [Related]
14. Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer. Rådmark O; Samuelsson B J Intern Med; 2010 Jul; 268(1):5-14. PubMed ID: 20497297 [TBL] [Abstract][Full Text] [Related]
15. Microsomal prostaglandin E synthase-1 enhances bone cancer growth and bone cancer-related pain behaviors in mice. Isono M; Suzuki T; Hosono K; Hayashi I; Sakagami H; Uematsu S; Akira S; DeClerck YA; Okamoto H; Majima M Life Sci; 2011 Apr; 88(15-16):693-700. PubMed ID: 21324324 [TBL] [Abstract][Full Text] [Related]
16. Prostaglandin E synthase: a novel drug target for inflammation and cancer. Murakami M; Kudo I Curr Pharm Des; 2006; 12(8):943-54. PubMed ID: 16533161 [TBL] [Abstract][Full Text] [Related]
17. MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation. Xu D; Rowland SE; Clark P; Giroux A; Côté B; Guiral S; Salem M; Ducharme Y; Friesen RW; Méthot N; Mancini J; Audoly L; Riendeau D J Pharmacol Exp Ther; 2008 Sep; 326(3):754-63. PubMed ID: 18524979 [TBL] [Abstract][Full Text] [Related]
18. Nonacidic inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1) identified by a multistep virtual screening protocol. Rörsch F; Wobst I; Zettl H; Schubert-Zsilavecz M; Grösch S; Geisslinger G; Schneider G; Proschak E J Med Chem; 2010 Jan; 53(2):911-5. PubMed ID: 20025212 [TBL] [Abstract][Full Text] [Related]
19. Selective inducible microsomal prostaglandin E(2) synthase-1 (mPGES-1) inhibitors derived from an oxicam template. Wang J; Limburg D; Carter J; Mbalaviele G; Gierse J; Vazquez M Bioorg Med Chem Lett; 2010 Mar; 20(5):1604-9. PubMed ID: 20144869 [TBL] [Abstract][Full Text] [Related]
20. Development of 2-aryl substituted quinazolin-4(3H)-one, pyrido[4,3-d]pyrimidin-4(3H)-one and pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as microsomal prostaglandin E(2) synthase-1 inhibitors. Banerjee A; Pawar MY; Patil S; Yadav PS; Kadam PA; Kattige VG; Deshpande DS; Pednekar PV; Pisat MK; Gharat LA Bioorg Med Chem Lett; 2014 Oct; 24(20):4838-44. PubMed ID: 25260492 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]