588 related articles for article (PubMed ID: 19532856)
1. The discovery of antibacterial agents using diversity-oriented synthesis.
Galloway WR; Bender A; Welch M; Spring DR
Chem Commun (Camb); 2009 May; (18):2446-62. PubMed ID: 19532856
[TBL] [Abstract][Full Text] [Related]
2. The design and synthesis of libraries for the discovery of antibacterial and antifungal substances.
Edwards PJ
Drug Discov Today; 2011 Mar; 16(5-6):278-9. PubMed ID: 21277383
[No Abstract] [Full Text] [Related]
3. Synthesis and antibiotic activity of a small molecules library of 1,2,3-triazole derivatives.
Aufort M; Herscovici J; Bouhours P; Moreau N; Girard C
Bioorg Med Chem Lett; 2008 Feb; 18(3):1195-8. PubMed ID: 18086525
[TBL] [Abstract][Full Text] [Related]
4. Molecular library design using multi-objective optimization methods.
Nicolaou CA; Kannas CC
Methods Mol Biol; 2011; 685():53-69. PubMed ID: 20981518
[TBL] [Abstract][Full Text] [Related]
5. Identification of lead compounds as antagonists of protein Bcl-xL with a diversity-oriented multidisciplinary approach.
Di Micco S; Vitale R; Pellecchia M; Rega MF; Riva R; Basso A; Bifulco G
J Med Chem; 2009 Dec; 52(23):7856-67. PubMed ID: 19852471
[TBL] [Abstract][Full Text] [Related]
6. Diversity-oriented synthesis; a spectrum of approaches and results.
Spandl RJ; Bender A; Spring DR
Org Biomol Chem; 2008 Apr; 6(7):1149-58. PubMed ID: 18362950
[TBL] [Abstract][Full Text] [Related]
7. Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces.
Kim J; Kim H; Park SB
J Am Chem Soc; 2014 Oct; 136(42):14629-38. PubMed ID: 25310802
[TBL] [Abstract][Full Text] [Related]
8. Smaller is better for antibiotic discovery.
Waldrop GL
ACS Chem Biol; 2009 Jun; 4(6):397-9. PubMed ID: 19537754
[TBL] [Abstract][Full Text] [Related]
9. Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors.
Shih HW; Chen KT; Chen SK; Huang CY; Cheng TJ; Ma C; Wong CH; Cheng WC
Org Biomol Chem; 2010 Jun; 8(11):2586-93. PubMed ID: 20485795
[TBL] [Abstract][Full Text] [Related]
10. Fragment-based ligand discovery.
Fischer M; Hubbard RE
Mol Interv; 2009 Feb; 9(1):22-30. PubMed ID: 19299661
[TBL] [Abstract][Full Text] [Related]
11. Principles, implementation, and application of biology-oriented synthesis (BIOS).
Wilk W; Zimmermann TJ; Kaiser M; Waldmann H
Biol Chem; 2010 May; 391(5):491-7. PubMed ID: 20030592
[TBL] [Abstract][Full Text] [Related]
12. A scalable approach to combinatorial library design.
Sharma P; Salapaka S; Beck C
Methods Mol Biol; 2011; 685():71-89. PubMed ID: 20981519
[TBL] [Abstract][Full Text] [Related]
13. Combinatorial library design from reagent pharmacophore fingerprints.
Chen H; Engkvist O; Blomberg N
Methods Mol Biol; 2011; 685():135-52. PubMed ID: 20981522
[TBL] [Abstract][Full Text] [Related]
14. Diversity-oriented fluorescence library approaches for probe discovery and development.
Vendrell M; Lee JS; Chang YT
Curr Opin Chem Biol; 2010 Jun; 14(3):383-9. PubMed ID: 20227904
[TBL] [Abstract][Full Text] [Related]
15. High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening.
Srinivasan R; Tan LP; Wu H; Yang PY; Kalesh KA; Yao SQ
Org Biomol Chem; 2009 May; 7(9):1821-8. PubMed ID: 19590777
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of a positional scanning library of pentamers of N-alkylglycines assisted by microwave activation and validation via the identification of trypsin inhibitors.
Messeguer J; Cortés N; García-Sanz N; Navarro-Vendrell G; Ferrer-Montiel A; Messeguer A
J Comb Chem; 2008; 10(6):974-80. PubMed ID: 18847288
[TBL] [Abstract][Full Text] [Related]
17. New directions in library design and analysis.
Gillet VJ
Curr Opin Chem Biol; 2008 Jun; 12(3):372-8. PubMed ID: 18331851
[TBL] [Abstract][Full Text] [Related]
18. How to discover new antibiotics: harvesting the parvome.
Davies J
Curr Opin Chem Biol; 2011 Feb; 15(1):5-10. PubMed ID: 21111668
[TBL] [Abstract][Full Text] [Related]
19. Utilizing diversity-oriented synthesis in antimicrobial drug discovery.
Comer E; Duvall JR; duPont Lee M
Future Med Chem; 2014; 6(17):1927-42. PubMed ID: 25495985
[TBL] [Abstract][Full Text] [Related]
20. Historical overview of chemical library design.
Dolle RE
Methods Mol Biol; 2011; 685():3-25. PubMed ID: 20981516
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]