BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 19533749)

  • 1. Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.
    Stockwin LH; Han B; Yu SX; Hollingshead MG; ElSohly MA; Gul W; Slade D; Galal AM; Newton DL; Bumke MA
    Int J Cancer; 2009 Sep; 125(6):1266-75. PubMed ID: 19533749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
    Haynes RK; Cheu KW; N'Da D; Coghi P; Monti D
    Infect Disord Drug Targets; 2013 Aug; 13(4):217-77. PubMed ID: 24304352
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Paradoxical effects of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) activator gingerol on NG115-401L neuronal cells: failure to augment ER Ca(2+) uptake and protect against ER stress-induced cell death.
    Zhang C; Bose DD; Thomas DW
    Eur J Pharmacol; 2015 Sep; 762():165-73. PubMed ID: 26033206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced endoplasmic reticulum SERCA activity by overexpression of hepatic stimulator substance gene prevents hepatic cells from ER stress-induced apoptosis.
    Zhang J; Li Y; Jiang S; Yu H; An W
    Am J Physiol Cell Physiol; 2014 Feb; 306(3):C279-90. PubMed ID: 24284796
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N-acetylcysteine attenuates reactive-oxygen-species-mediated endoplasmic reticulum stress during liver ischemia-reperfusion injury.
    Sun Y; Pu LY; Lu L; Wang XH; Zhang F; Rao JH
    World J Gastroenterol; 2014 Nov; 20(41):15289-98. PubMed ID: 25386077
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Purified E255L mutant SERCA1a and purified PfATP6 are sensitive to SERCA-type inhibitors but insensitive to artemisinins.
    Cardi D; Pozza A; Arnou B; Marchal E; Clausen JD; Andersen JP; Krishna S; Møller JV; le Maire M; Jaxel C
    J Biol Chem; 2010 Aug; 285(34):26406-16. PubMed ID: 20530490
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Artemisinins target the SERCA of Plasmodium falciparum.
    Eckstein-Ludwig U; Webb RJ; Van Goethem ID; East JM; Lee AG; Kimura M; O'Neill PM; Bray PG; Ward SA; Krishna S
    Nature; 2003 Aug; 424(6951):957-61. PubMed ID: 12931192
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii.
    Nagamune K; Beatty WL; Sibley LD
    Eukaryot Cell; 2007 Nov; 6(11):2147-56. PubMed ID: 17766463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells.
    Park KS; Poburko D; Wollheim CB; Demaurex N
    Br J Pharmacol; 2009 Apr; 156(8):1296-304. PubMed ID: 19302589
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of the sarco/endoplasmic reticulum (ER) Ca
    Sehgal P; Szalai P; Olesen C; Praetorius HA; Nissen P; Christensen SB; Engedal N; Møller JV
    J Biol Chem; 2017 Dec; 292(48):19656-19673. PubMed ID: 28972171
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells.
    Tonnesen MF; Grunnet LG; Friberg J; Cardozo AK; Billestrup N; Eizirik DL; Størling J; Mandrup-Poulsen T
    Endocrinology; 2009 Sep; 150(9):4094-103. PubMed ID: 19556421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Berberine-induced apoptosis in human glioblastoma T98G cells is mediated by endoplasmic reticulum stress accompanying reactive oxygen species and mitochondrial dysfunction.
    Eom KS; Kim HJ; So HS; Park R; Kim TY
    Biol Pharm Bull; 2010; 33(10):1644-9. PubMed ID: 20930370
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fluorochloridone induces primary cultured Sertoli cells apoptosis: Involvement of ROS and intracellular calcium ions-mediated ERK1/2 activation.
    Liu L; Chang X; Zhang Y; Wu C; Li R; Tang L; Zhou Z
    Toxicol In Vitro; 2018 Mar; 47():228-237. PubMed ID: 29248592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Endoplasmic reticulum stress inducers provide protection against 6-hydroxydopamine-induced cytotoxicity.
    Hara H; Kamiya T; Adachi T
    Neurochem Int; 2011 Jan; 58(1):35-43. PubMed ID: 20974203
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2.
    Li W; Ouyang Z; Zhang Q; Wang L; Shen Y; Wu X; Gu Y; Shu Y; Yu B; Wu X; Sun Y; Xu Q
    Cell Death Dis; 2014 Dec; 5(12):e1581. PubMed ID: 25522275
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.
    Wootton LL; Michelangeli F
    J Biol Chem; 2006 Mar; 281(11):6970-6. PubMed ID: 16410239
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression.
    Lee GH; Kim HK; Chae SW; Kim DS; Ha KC; Cuddy M; Kress C; Reed JC; Kim HR; Chae HJ
    J Biol Chem; 2007 Jul; 282(30):21618-28. PubMed ID: 17526500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of endoplasmic reticulum calcium leak by 2-APB depends on the luminal calcium concentration.
    Leon-Aparicio D; Chavez-Reyes J; Guerrero-Hernandez A
    Cell Calcium; 2017 Jul; 65():80-90. PubMed ID: 28249687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heme-Dependent ER Stress Apoptosis: A Mechanism for the Selective Toxicity of the Dihydroartemisinin, NSC735847, in Colorectal Cancer Cells.
    Elhassanny AEM; Soliman E; Marie M; McGuire P; Gul W; ElSohly M; Van Dross R
    Front Oncol; 2020; 10():965. PubMed ID: 32626657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ER-Dependent Ca++-mediated Cytosolic ROS as an Effector for Induction of Mitochondrial Apoptotic and ATM-JNK Signal Pathways in Gallic Acid-treated Human Oral Cancer Cells.
    Lu YC; Lin ML; Su HL; Chen SS
    Anticancer Res; 2016 Feb; 36(2):697-705. PubMed ID: 26851027
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.