174 related articles for article (PubMed ID: 19534674)
1. Inhibition of HIV-1 ribonuclease H activity by novel frangula-emodine derivatives.
Tatyana K; Francesca E; Luca Z; Giovanni F; Cheng YC; Ginger ED; Enzo T
Med Chem; 2009 Sep; 5(5):398-410. PubMed ID: 19534674
[TBL] [Abstract][Full Text] [Related]
2. New anthraquinone derivatives as inhibitors of the HIV-1 reverse transcriptase-associated ribonuclease H function.
Esposito F; Corona A; Zinzula L; Kharlamova T; Tramontano E
Chemotherapy; 2012; 58(4):299-307. PubMed ID: 23128501
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.
Corona A; Onnis V; Deplano A; Bianco G; Demurtas M; Distinto S; Cheng YC; Alcaro S; Esposito F; Tramontano E
Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28859311
[TBL] [Abstract][Full Text] [Related]
4. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
Boyer PL; Smith SJ; Zhao XZ; Das K; Gruber K; Arnold E; Burke TR; Hughes SH
J Virol; 2018 Jul; 92(13):. PubMed ID: 29643235
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.
Borkow G; Fletcher RS; Barnard J; Arion D; Motakis D; Dmitrienko GI; Parniak MA
Biochemistry; 1997 Mar; 36(11):3179-85. PubMed ID: 9115994
[TBL] [Abstract][Full Text] [Related]
6. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
[TBL] [Abstract][Full Text] [Related]
7. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro.
Tramontano E; Esposito F; Badas R; Di Santo R; Costi R; La Colla P
Antiviral Res; 2005 Feb; 65(2):117-24. PubMed ID: 15708638
[TBL] [Abstract][Full Text] [Related]
8. Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases.
Esposito F; Kharlamova T; Distinto S; Zinzula L; Cheng YC; Dutschman G; Floris G; Markt P; Corona A; Tramontano E
FEBS J; 2011 May; 278(9):1444-57. PubMed ID: 21348941
[TBL] [Abstract][Full Text] [Related]
9. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.
Sun L; Gao P; Dong G; Zhang X; Cheng X; Ding X; Wang X; Daelemans D; De Clercq E; Pannecouque C; Menéndez-Arias L; Zhan P; Liu X
Eur J Med Chem; 2018 Jul; 155():714-724. PubMed ID: 29940462
[TBL] [Abstract][Full Text] [Related]
10. Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase.
Yanagita H; Urano E; Matsumoto K; Ichikawa R; Takaesu Y; Ogata M; Murakami T; Wu H; Chiba J; Komano J; Hoshino T
Bioorg Med Chem; 2011 Jan; 19(2):816-25. PubMed ID: 21193314
[TBL] [Abstract][Full Text] [Related]
11. Diketo acids derivatives as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain.
Di Santo R
Curr Med Chem; 2011; 18(22):3335-42. PubMed ID: 21728968
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
Tang J; Vernekar SKV; Chen YL; Miller L; Huber AD; Myshakina N; Sarafianos SG; Parniak MA; Wang Z
Eur J Med Chem; 2017 Jun; 133():85-96. PubMed ID: 28384548
[TBL] [Abstract][Full Text] [Related]
13. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
Corona A; Meleddu R; Esposito F; Distinto S; Bianco G; Masaoka T; Maccioni E; Menéndez-Arias L; Alcaro S; Le Grice SF; Tramontano E
PLoS One; 2016; 11(1):e0147225. PubMed ID: 26800261
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R; Cannas V; Distinto S; Sarais G; Del Vecchio C; Esposito F; Bianco G; Corona A; Cottiglia F; Alcaro S; Parolin C; Artese A; Scalise D; Fresta M; Arridu A; Ortuso F; Maccioni E; Tramontano E
ChemMedChem; 2014 Aug; 9(8):1869-79. PubMed ID: 24850787
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain.
Cuzzucoli Crucitti G; Métifiot M; Pescatori L; Messore A; Madia VN; Pupo G; Saccoliti F; Scipione L; Tortorella S; Esposito F; Corona A; Cadeddu M; Marchand C; Pommier Y; Tramontano E; Costi R; Di Santo R
J Med Chem; 2015 Feb; 58(4):1915-28. PubMed ID: 25629256
[TBL] [Abstract][Full Text] [Related]
16. Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.
Esposito F; Mandrone M; Del Vecchio C; Carli I; Distinto S; Corona A; Lianza M; Piano D; Tacchini M; Maccioni E; Cottiglia F; Saccon E; Poli F; Parolin C; Tramontano E
Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28637198
[TBL] [Abstract][Full Text] [Related]
17. Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.
Wang L; Sarafianos SG; Wang Z
Acc Chem Res; 2020 Jan; 53(1):218-230. PubMed ID: 31880912
[TBL] [Abstract][Full Text] [Related]
18. Combinatorial selection, inhibition, and antiviral activity of DNA thioaptamers targeting the RNase H domain of HIV-1 reverse transcriptase.
Somasunderam A; Ferguson MR; Rojo DR; Thiviyanathan V; Li X; O'Brien WA; Gorenstein DG
Biochemistry; 2005 Aug; 44(30):10388-95. PubMed ID: 16042416
[TBL] [Abstract][Full Text] [Related]
19. N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation.
Biondi MJ; Beilhartz GL; McCormick S; Götte M
J Biol Chem; 2010 Aug; 285(35):26966-26975. PubMed ID: 20530477
[TBL] [Abstract][Full Text] [Related]
20. Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.
Li TK; Barbieri CM; Lin HC; Rabson AB; Yang G; Fan Y; Gaffney BL; Jones RA; Pilch DS
Biochemistry; 2004 Aug; 43(30):9732-42. PubMed ID: 15274628
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
