BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 19535915)

  • 1. A cathepsin L-specific inhibitor preferentially inhibits degradation of autophagosomal LC3 and GABARAP in HeLa and Huh-7 cells.
    Ueno T; Takahashi K
    Autophagy; 2009 Aug; 5(6):878-9. PubMed ID: 19535915
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of CAA0225, a novel inhibitor specific for cathepsin L, as a probe for autophagic proteolysis.
    Takahashi K; Ueno T; Tanida I; Minematsu-Ikeguchi N; Murata M; Kominami E
    Biol Pharm Bull; 2009 Mar; 32(3):475-9. PubMed ID: 19252298
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trypanosoma brucei: chemical evidence that cathepsin L is essential for survival and a relevant drug target.
    Steverding D; Sexton DW; Wang X; Gehrke SS; Wagner GK; Caffrey CR
    Int J Parasitol; 2012 May; 42(5):481-8. PubMed ID: 22549023
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.
    Kabeya Y; Mizushima N; Yamamoto A; Oshitani-Okamoto S; Ohsumi Y; Yoshimori T
    J Cell Sci; 2004 Jun; 117(Pt 13):2805-12. PubMed ID: 15169837
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells.
    Schwartz-Roberts JL; Shajahan AN; Cook KL; Wärri A; Abu-Asab M; Clarke R
    Mol Cancer Ther; 2013 Apr; 12(4):448-59. PubMed ID: 23395885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. No ATG8s, no problem? How LC3/GABARAP proteins contribute to autophagy.
    Martens S
    J Cell Biol; 2016 Dec; 215(6):761-763. PubMed ID: 27888204
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of LC3/GABARAP sensors containing a LIR and a hydrophobic domain to monitor autophagy.
    Lee YK; Jun YW; Choi HE; Huh YH; Kaang BK; Jang DJ; Lee JA
    EMBO J; 2017 Apr; 36(8):1100-1116. PubMed ID: 28320742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cathepsin inhibition-induced lysosomal dysfunction enhances pancreatic beta-cell apoptosis in high glucose.
    Jung M; Lee J; Seo HY; Lim JS; Kim EK
    PLoS One; 2015; 10(1):e0116972. PubMed ID: 25625842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dissecting the involvement of LC3B and GATE-16 in p62 recruitment into autophagosomes.
    Shvets E; Abada A; Weidberg H; Elazar Z
    Autophagy; 2011 Jul; 7(7):683-8. PubMed ID: 21460636
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway.
    Tanida I; Wakabayashi M; Kanematsu T; Minematsu-Ikeguchi N; Sou YS; Hirata M; Ueno T; Kominami E
    Autophagy; 2006; 2(4):264-71. PubMed ID: 16874098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 3-hydroxy-3-methylglutaryl coenzyme A reductase is sterol-dependently cleaved by cathepsin L-type cysteine protease in the isolated endoplasmic reticulum.
    Moriyama T; Wada M; Urade R; Kito M; Katunuma N; Ogawa T; Simoni RD
    Arch Biochem Biophys; 2001 Feb; 386(2):205-12. PubMed ID: 11368343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.
    Nguyen TN; Padman BS; Usher J; Oorschot V; Ramm G; Lazarou M
    J Cell Biol; 2016 Dec; 215(6):857-874. PubMed ID: 27864321
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lipid Geometry and Bilayer Curvature Modulate LC3/GABARAP-Mediated Model Autophagosomal Elongation.
    Landajuela A; Hervás JH; Antón Z; Montes LR; Gil D; Valle M; Rodriguez JF; Goñi FM; Alonso A
    Biophys J; 2016 Jan; 110(2):411-422. PubMed ID: 26789764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and functional analysis of the GABARAP interaction motif (GIM).
    Rogov VV; Stolz A; Ravichandran AC; Rios-Szwed DO; Suzuki H; Kniss A; Löhr F; Wakatsuki S; Dötsch V; Dikic I; Dobson RC; McEwan DG
    EMBO Rep; 2017 Aug; 18(8):1382-1396. PubMed ID: 28655748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.
    Kirkin V; Lamark T; Sou YS; Bjørkøy G; Nunn JL; Bruun JA; Shvets E; McEwan DG; Clausen TH; Wild P; Bilusic I; Theurillat JP; Øvervatn A; Ishii T; Elazar Z; Komatsu M; Dikic I; Johansen T
    Mol Cell; 2009 Feb; 33(4):505-16. PubMed ID: 19250911
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Processing of autophagic protein LC3 by the 20S proteasome.
    Gao Z; Gammoh N; Wong PM; Erdjument-Bromage H; Tempst P; Jiang X
    Autophagy; 2010 Jan; 6(1):126-37. PubMed ID: 20061800
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LC3/GABARAP family proteins: autophagy-(un)related functions.
    Schaaf MB; Keulers TG; Vooijs MA; Rouschop KM
    FASEB J; 2016 Dec; 30(12):3961-3978. PubMed ID: 27601442
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis.
    Weidberg H; Shpilka T; Shvets E; Abada A; Shimron F; Elazar Z
    Dev Cell; 2011 Apr; 20(4):444-54. PubMed ID: 21497758
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impaired turnover of autophagolysosomes in cathepsin L deficiency.
    Dennemärker J; Lohmüller T; Müller S; Aguilar SV; Tobin DJ; Peters C; Reinheckel T
    Biol Chem; 2010 Aug; 391(8):913-22. PubMed ID: 20536383
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The evolutionarily conserved interaction between LC3 and p62 selectively mediates autophagy-dependent degradation of mutant huntingtin.
    Tung YT; Hsu WM; Lee H; Huang WP; Liao YF
    Cell Mol Neurobiol; 2010 Jul; 30(5):795-806. PubMed ID: 20204693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.