BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

565 related articles for article (PubMed ID: 19538463)

  • 21. A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1α and HIF2α stability and tumor growth, angiogenesis, and metastasis.
    Joshi S; Singh AR; Zulcic M; Durden DL
    Mol Cancer Res; 2014 Oct; 12(10):1520-31. PubMed ID: 25103499
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C; Moore JW; Robertson N; Harris AL
    Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anticancer imidazoacridinone C-1311 inhibits hypoxia-inducible factor-1α (HIF-1α), vascular endothelial growth factor (VEGF) and angiogenesis.
    Paradziej-Łukowicz J; Skwarska A; Peszyńska-Sularz G; Brillowska-Dąbrowska A; Konopa J
    Cancer Biol Ther; 2011 Oct; 12(7):586-97. PubMed ID: 21775820
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Liquiritigenin inhibits serum-induced HIF-1α and VEGF expression via the AKT/mTOR-p70S6K signalling pathway in HeLa cells.
    Xie SR; Wang Y; Liu CW; Luo K; Cai YQ
    Phytother Res; 2012 Aug; 26(8):1133-41. PubMed ID: 22170854
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Ginsenoside-Rg1 mediates a hypoxia-independent upregulation of hypoxia-inducible factor-1α to promote angiogenesis.
    Leung KW; Ng HM; Tang MK; Wong CC; Wong RN; Wong AS
    Angiogenesis; 2011 Dec; 14(4):515-22. PubMed ID: 21964931
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Role of HIF-1alpha and VEGF in human mesenchymal stem cell proliferation by 17beta-estradiol: involvement of PKC, PI3K/Akt, and MAPKs.
    Yun SP; Lee MY; Ryu JM; Song CH; Han HJ
    Am J Physiol Cell Physiol; 2009 Feb; 296(2):C317-26. PubMed ID: 18987249
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Aspirin Affects Tumor Angiogenesis and Sensitizes Human Glioblastoma Endothelial Cells to Temozolomide, Bevacizumab, and Sunitinib, Impairing Vascular Endothelial Growth Factor-Related Signaling.
    Navone SE; Guarnaccia L; Cordiglieri C; Crisà FM; Caroli M; Locatelli M; Schisano L; Rampini P; Miozzo M; La Verde N; Riboni L; Campanella R; Marfia G
    World Neurosurg; 2018 Dec; 120():e380-e391. PubMed ID: 30144594
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells.
    Manohar SM; Padgaonkar AA; Jalota-Badhwar A; Sonawane V; Rathos MJ; Kumar S; Joshi KS
    BMC Cancer; 2011 Aug; 11():338. PubMed ID: 21819554
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway.
    Park JH; Lee JY; Shin DH; Jang KS; Kim HJ; Kong G
    Oncogene; 2011 Nov; 30(45):4578-89. PubMed ID: 21602890
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
    Treins C; Giorgetti-Peraldi S; Murdaca J; Semenza GL; Van Obberghen E
    J Biol Chem; 2002 Aug; 277(31):27975-81. PubMed ID: 12032158
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification of approved and investigational drugs that inhibit hypoxia-inducible factor-1 signaling.
    Hsu CW; Huang R; Khuc T; Shou D; Bullock J; Grooby S; Griffin S; Zou C; Little A; Astley H; Xia M
    Oncotarget; 2016 Feb; 7(7):8172-83. PubMed ID: 26882567
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Far-infrared radiation alleviates cisplatin-induced vascular damage and impaired circulation via activation of HIF-1α.
    Chen CH; Chen MC; Hsu YH; Chou TC
    Cancer Sci; 2022 Jun; 113(6):2194-2206. PubMed ID: 35411640
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Roles of PI3K/Akt and c-Jun signaling pathways in human papillomavirus type 16 oncoprotein-induced HIF-1α, VEGF, and IL-8 expression and in vitro angiogenesis in non-small cell lung cancer cells.
    Zhang E; Feng X; Liu F; Zhang P; Liang J; Tang X
    PLoS One; 2014; 9(7):e103440. PubMed ID: 25058399
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Activation of HIF-1
    Schoos A; Gabriel C; Knab VM; Fux DA
    J Pharmacol Exp Ther; 2019 Sep; 370(3):480-489. PubMed ID: 31300611
    [TBL] [Abstract][Full Text] [Related]  

  • 35. UVB radiation induces expression of HIF-1alpha and VEGF through the EGFR/PI3K/DEC1 pathway.
    Li Y; Bi Z; Yan B; Wan Y
    Int J Mol Med; 2006 Oct; 18(4):713-9. PubMed ID: 16964427
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptors.
    Mahfouz N; Tahtouh R; Alaaeddine N; El Hajj J; Sarkis R; Hachem R; Raad I; Hilal G
    PLoS One; 2017; 12(6):e0179202. PubMed ID: 28594907
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice.
    Zhang EY; Gao B; Shi HL; Huang LF; Yang L; Wu XJ; Wang ZT
    Exp Mol Med; 2017 Oct; 49(10):e387. PubMed ID: 29075038
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization.
    Yang XM; Wang YS; Zhang J; Li Y; Xu JF; Zhu J; Zhao W; Chu DK; Wiedemann P
    Invest Ophthalmol Vis Sci; 2009 Apr; 50(4):1873-9. PubMed ID: 19098317
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 40. SU5416 inhibited VEGF and HIF-1alpha expression through the PI3K/AKT/p70S6K1 signaling pathway.
    Zhong XS; Zheng JZ; Reed E; Jiang BH
    Biochem Biophys Res Commun; 2004 Nov; 324(2):471-80. PubMed ID: 15474452
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.