434 related articles for article (PubMed ID: 19539408)
1. New azoles with potent antifungal activity: design, synthesis and molecular docking.
Che X; Sheng C; Wang W; Cao Y; Xu Y; Ji H; Dong G; Miao Z; Yao J; Zhang W
Eur J Med Chem; 2009 Oct; 44(10):4218-26. PubMed ID: 19539408
[TBL] [Abstract][Full Text] [Related]
2. Discovery of highly potent novel antifungal azoles by structure-based rational design.
Wang W; Sheng C; Che X; Ji H; Cao Y; Miao Z; Yao J; Zhang W
Bioorg Med Chem Lett; 2009 Oct; 19(20):5965-9. PubMed ID: 19748782
[TBL] [Abstract][Full Text] [Related]
3. Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives.
Xu Y; Sheng C; Wang W; Che X; Cao Y; Dong G; Wang S; Ji H; Miao Z; Yao J; Zhang W
Bioorg Med Chem Lett; 2010 May; 20(9):2942-5. PubMed ID: 20362444
[TBL] [Abstract][Full Text] [Related]
4. Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization.
Sheng C; Wang W; Che X; Dong G; Wang S; Ji H; Miao Z; Yao J; Zhang W
ChemMedChem; 2010 Mar; 5(3):390-7. PubMed ID: 20157915
[TBL] [Abstract][Full Text] [Related]
5. Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.
Sheng C; Zhang W; Ji H; Zhang M; Song Y; Xu H; Zhu J; Miao Z; Jiang Q; Yao J; Zhou Y; Zhu J; Lü J
J Med Chem; 2006 Apr; 49(8):2512-25. PubMed ID: 16610794
[TBL] [Abstract][Full Text] [Related]
6. New azoles with antifungal activity: Design, synthesis, and molecular docking.
Chai X; Zhang J; Cao Y; Zou Y; Wu Q; Zhang D; Jiang Y; Sun Q
Bioorg Med Chem Lett; 2011 Jan; 21(2):686-9. PubMed ID: 21190856
[TBL] [Abstract][Full Text] [Related]
7. Structure-based design, synthesis, and antifungal activity of new triazole derivatives.
Sheng C; Che X; Wang W; Wang S; Cao Y; Yao J; Miao Z; Zhang W
Chem Biol Drug Des; 2011 Aug; 78(2):309-13. PubMed ID: 21585708
[TBL] [Abstract][Full Text] [Related]
8. Identification of Y118 amino acid residue in Candida albicans sterol 14alpha-demethylase associated with the enzyme activity and selective antifungal activity of azole analogues.
Chen SH; Sheng CQ; Xu XH; Jiang YY; Zhang WN; He C
Biol Pharm Bull; 2007 Jul; 30(7):1246-53. PubMed ID: 17603162
[TBL] [Abstract][Full Text] [Related]
9. New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies.
Doğan İS; Saraç S; Sari S; Kart D; Eşsiz Gökhan Ş; Vural İ; Dalkara S
Eur J Med Chem; 2017 Apr; 130():124-138. PubMed ID: 28242548
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and evaluation of novel azoles as potent antifungal agents.
Li L; Ding H; Wang B; Yu S; Zou Y; Chai X; Wu Q
Bioorg Med Chem Lett; 2014 Jan; 24(1):192-4. PubMed ID: 24332489
[TBL] [Abstract][Full Text] [Related]
11. Discovery of new azoles with potent activity against Candida spp. and Candida albicans biofilms through virtual screening.
Sari S; Kart D; Öztürk N; Kaynak FB; Gencel M; Taşkor G; Karakurt A; Saraç S; Eşsiz Ş; Dalkara S
Eur J Med Chem; 2019 Oct; 179():634-648. PubMed ID: 31279296
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14alpha-demethylase (CYP51) of fungi.
Zhu J; Lu J; Zhou Y; Li Y; Cheng J; Zheng C
Bioorg Med Chem Lett; 2006 Oct; 16(20):5285-9. PubMed ID: 16905318
[TBL] [Abstract][Full Text] [Related]
13. Novel conformationally restricted triazole derivatives with potent antifungal activity.
Wang W; Wang S; Liu Y; Dong G; Cao Y; Miao Z; Yao J; Zhang W; Sheng C
Eur J Med Chem; 2010 Dec; 45(12):6020-6. PubMed ID: 20950895
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and microbiological evaluation of new Candida albicans CYP51 inhibitors.
Schiaffella F; Macchiarulo A; Milanese L; Vecchiarelli A; Costantino G; Pietrella D; Fringuelli R
J Med Chem; 2005 Dec; 48(24):7658-66. PubMed ID: 16302806
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives.
Xu J; Cao Y; Zhang J; Yu S; Zou Y; Chai X; Wu Q; Zhang D; Jiang Y; Sun Q
Eur J Med Chem; 2011 Jul; 46(7):3142-8. PubMed ID: 21420761
[TBL] [Abstract][Full Text] [Related]
16. Design and Synthesis of New Antifungals Based on N-Un-substituted Azoles as 14α Demethylase Inhibitor.
Davood A; Rahimi A; Iman M; Azerang P; Sardari S; Mahboubi A
Curr Comput Aided Drug Des; 2021; 17(2):235-243. PubMed ID: 32065093
[TBL] [Abstract][Full Text] [Related]
17. Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents.
Sanglard D; Ischer F; Koymans L; Bille J
Antimicrob Agents Chemother; 1998 Feb; 42(2):241-53. PubMed ID: 9527767
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of the combination mode of azoles antifungal inhibitors with CACYP51 and the influence of Site-directed mutation.
Sun B; Huang W; Liu M
J Mol Graph Model; 2017 May; 73():157-165. PubMed ID: 28282632
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and antifungal activity of new thienyl and aryl conazoles.
Chevreuil F; Landreau A; Seraphin D; Larcher G; Bouchara JP; Richomme P
J Enzyme Inhib Med Chem; 2006 Jun; 21(3):293-303. PubMed ID: 16918077
[TBL] [Abstract][Full Text] [Related]
20. [Synthesis and antifungal activity of 1-(2-[(4-substituted-phenyl) methoxy]-2-(substituted-phenyl) ethyl)-1H-azoles].
Wu QY; Li K; Liu CM; Liu GX; Wang XY
Yao Xue Xue Bao; 1993; 28(9):661-7. PubMed ID: 8010011
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
