BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 19540195)

  • 1. Selective cytotoxicity of a bicyclic Ras inhibitor in cancer cells expressing K-Ras(G13D).
    Palmioli A; Sacco E; Airoldi C; Di Nicolantonio F; D'Urzo A; Shirasawa S; Sasazuki T; Di Domizio A; De Gioia L; Martegani E; Bardelli A; Peri F; Vanoni M
    Biochem Biophys Res Commun; 2009 Sep; 386(4):593-7. PubMed ID: 19540195
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells.
    Sacco E; Metalli D; Spinelli M; Manzoni R; Samalikova M; Grandori R; Morrione A; Traversa S; Alberghina L; Vanoni M
    Biotechnol Adv; 2012; 30(1):233-43. PubMed ID: 21620943
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.
    Niida A; Sasaki S; Yonemori K; Sameshima T; Yaguchi M; Asami T; Sakamoto K; Kamaura M
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2757-2761. PubMed ID: 28457754
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).
    Vanoni M; Bertini R; Sacco E; Fontanella L; Rieppi M; Colombo S; Martegani E; Carrera V; Moroni A; Bizzarri C; Sabbatini V; Cattozzo M; Colagrande A; Alberghina L
    J Biol Chem; 1999 Dec; 274(51):36656-62. PubMed ID: 10593969
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of sugar-derived Ras inhibitors.
    Peri F; Airoldi C; Colombo S; Martegani E; van Neuren AS; Stein M; Marinzi C; Nicotra F
    Chembiochem; 2005 Oct; 6(10):1839-48. PubMed ID: 16196015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.
    Sacco E; Fantinato S; Manzoni R; Metalli D; De Gioia L; Fantucci P; Alberghina L; Vanoni M
    FEBS Lett; 2005 Dec; 579(30):6851-8. PubMed ID: 16325815
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A dominant negative RAS-specific guanine nucleotide exchange factor reverses neoplastic phenotype in K-ras transformed mouse fibroblasts.
    Bossù P; Vanoni M; Wanke V; Cesaroni MP; Tropea F; Melillo G; Asti C; Porzio S; Ruggiero P; Di Cioccio V; Maurizi G; Ciabini A; Alberghina L
    Oncogene; 2000 Apr; 19(17):2147-54. PubMed ID: 10815806
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibitors of K-Ras plasma membrane localization.
    Cho KJ; van der Hoeven D; Hancock JF
    Enzymes; 2013; 33 Pt A():249-65. PubMed ID: 25033808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology.
    Sakamoto K; Kamada Y; Sameshima T; Yaguchi M; Niida A; Sasaki S; Miwa M; Ohkubo S; Sakamoto JI; Kamaura M; Cho N; Tani A
    Biochem Biophys Res Commun; 2017 Mar; 484(3):605-611. PubMed ID: 28153726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells.
    Norum JH; Méthi T; Mattingly RR; Levy FO
    FEBS J; 2005 May; 272(9):2304-16. PubMed ID: 15853814
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
    Leaner VD; Donninger H; Ellis CA; Clark GJ; Birrer MJ
    Mol Cell Biol; 2005 Apr; 25(8):3324-37. PubMed ID: 15798216
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
    Alamo P; Gallardo A; Di Nicolantonio F; Pavón MA; Casanova I; Trias M; Mangues MA; Lopez-Pousa A; Villaverde A; Vázquez E; Bardelli A; Céspedes MV; Mangues R
    FASEB J; 2015 Feb; 29(2):464-76. PubMed ID: 25359494
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit
    Kaya P; Schaffner-Reckinger E; Manoharan GB; Vukic V; Kiriazis A; Ledda M; Burgos Renedo M; Pavic K; Gaigneaux A; Glaab E; Abankwa DK
    J Med Chem; 2024 Jun; 67(11):8569-8584. PubMed ID: 38758695
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor.
    Chen SY; Huff SY; Lai CC; Der CJ; Powers S
    Oncogene; 1994 Sep; 9(9):2691-8. PubMed ID: 8058333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21.
    Shou C; Farnsworth CL; Neel BG; Feig LA
    Nature; 1992 Jul; 358(6384):351-4. PubMed ID: 1379346
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model.
    Zhang B; Zhang Y; Shacter E; Zheng Y
    Biochemistry; 2005 Feb; 44(7):2566-76. PubMed ID: 15709769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug Discovery by Targeting Mutant KRAS.
    Ye N
    Curr Top Med Chem; 2019; 19(23):2079-2080. PubMed ID: 31762422
    [No Abstract]   [Full Text] [Related]  

  • 18. Anthraquinones as Inhibitors of SOS RAS-GEF Activity.
    Fernández-Medarde A; Fuentes-Mateos R; García-Navas R; Juan AO; Sánchez-López JM; Fernández-Medarde A; Santos E
    Biomolecules; 2021 Jul; 11(8):. PubMed ID: 34439794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Two new bicyclic cembranolides from a new Sarcophyton species and determination of the absolute configuration of sarcoglaucol-16-one.
    Gross H; Wright AD; Beil W; König GM
    Org Biomol Chem; 2004 Apr; 2(8):1133-8. PubMed ID: 15064788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rasp21 sequences opposite the nucleotide binding pocket are required for GRF-mediated nucleotide release.
    Leonardsen L; DeClue JE; Lybaek H; Lowy DR; Willumsen BM
    Oncogene; 1996 Nov; 13(10):2177-87. PubMed ID: 8950985
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.