BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 19543980)

  • 1. Homospermidine in transgenic tobacco results in considerably reduced spermidine levels but is not converted to pyrrolizidine alkaloid precursors.
    Abdelhady MI; Beuerle T; Ober D
    Plant Mol Biol; 2009 Sep; 71(1-2):145-55. PubMed ID: 19543980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence for general occurrence of homospermidine in plants and its supposed origin as by-product of deoxyhypusine synthase.
    Ober D; Gibas L; Witte L; Hartmann T
    Phytochemistry; 2003 Feb; 62(3):339-44. PubMed ID: 12620346
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular evolution by change of function. Alkaloid-specific homospermidine synthase retained all properties of deoxyhypusine synthase except binding the eIF5A precursor protein.
    Ober D; Harms R; Witte L; Hartmann T
    J Biol Chem; 2003 Apr; 278(15):12805-12. PubMed ID: 12562768
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyrrolizidine alkaloid biosynthesis, evolution of a pathway in plant secondary metabolism.
    Ober D; Kaltenegger E
    Phytochemistry; 2009; 70(15-16):1687-95. PubMed ID: 19545881
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phylogenetic origin of a secondary pathway: the case of pyrrolizidine alkaloids.
    Ober D; Hartmann T
    Plant Mol Biol; 2000 Nov; 44(4):445-50. PubMed ID: 11197320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell-specific expression of homospermidine synthase, the entry enzyme of the pyrrolizidine alkaloid pathway in Senecio vernalis, in comparison with its ancestor, deoxyhypusine synthase.
    Moll S; Anke S; Kahmann U; Hänsch R; Hartmann T; Ober D
    Plant Physiol; 2002 Sep; 130(1):47-57. PubMed ID: 12226485
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Heterologous expression of a bacterial homospermidine synthase gene in transgenic tobacco: effects on the polyamine pathway.
    Kaiser A; Sell S; Hehl R
    Arch Pharm (Weinheim); 2002 Apr; 335(4):143-51. PubMed ID: 12112034
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Homospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved from deoxyhypusine synthase.
    Ober D; Hartmann T
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14777-82. PubMed ID: 10611289
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Repeated evolution of the pyrrolizidine alkaloid-mediated defense system in separate angiosperm lineages.
    Reimann A; Nurhayati N; Backenköhler A; Ober D
    Plant Cell; 2004 Oct; 16(10):2772-84. PubMed ID: 15466410
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deoxyhypusine synthase from tobacco. cDNA isolation, characterization, and bacterial expression of an enzyme with extended substrate specificity.
    Ober D; Hartmann T
    J Biol Chem; 1999 Nov; 274(45):32040-7. PubMed ID: 10542236
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evolution of homospermidine synthase in the convolvulaceae: a story of gene duplication, gene loss, and periods of various selection pressures.
    Kaltenegger E; Eich E; Ober D
    Plant Cell; 2013 Apr; 25(4):1213-27. PubMed ID: 23572540
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evolution of pyrrolizidine alkaloids in Phalaenopsis orchids and other monocotyledons: identification of deoxyhypusine synthase, homospermidine synthase and related pseudogenes.
    Nurhayati N; Gondé D; Ober D
    Phytochemistry; 2009 Mar; 70(4):508-16. PubMed ID: 19254800
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduction of Pyrrolizidine Alkaloid Levels in Comfrey (Symphytum officinale) Hairy Roots by RNAi Silencing of Homospermidine Synthase.
    Kruse LH; Stegemann T; Jensen-Kroll J; Engelhardt A; Wesseling AM; Lippert A; Ludwig-Müller J; Ober D
    Planta Med; 2019 Oct; 85(14-15):1177-1186. PubMed ID: 31450245
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tissue distribution, core biosynthesis and diversification of pyrrolizidine alkaloids of the lycopsamine type in three Boraginaceae species.
    Frölich C; Ober D; Hartmann T
    Phytochemistry; 2007 Apr; 68(7):1026-37. PubMed ID: 17320124
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution and multifarious horizontal transfer of an alternative biosynthetic pathway for the alternative polyamine sym-homospermidine.
    Shaw FL; Elliott KA; Kinch LN; Fuell C; Phillips MA; Michael AJ
    J Biol Chem; 2010 May; 285(19):14711-23. PubMed ID: 20194510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of an activity assay for characterizing deoxyhypusine synthase and its diverse reaction products.
    Kaltenegger E; Prakashrao AS; Çiçek SS; Ober D
    FEBS Open Bio; 2021 Jan; 11(1):10-25. PubMed ID: 33247548
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Different polyamine pathways from bacteria have replaced eukaryotic spermidine biosynthesis in ciliates Tetrahymena thermophila and Paramecium tetaurelia.
    Li B; Kim SH; Zhang Y; Hanfrey CC; Elliott KA; Ealick SE; Michael AJ
    Mol Microbiol; 2015 Sep; 97(5):791-807. PubMed ID: 25994085
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cloning and expression of a cDNA encoding homospermidine synthase from Senecio vulgaris (Asteraceae) in Escherichia coli.
    Kaiser A
    Plant J; 1999 Jul; 19(2):195-201. PubMed ID: 10476066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recruitment of alkaloid-specific homospermidine synthase (HSS) from ubiquitous deoxyhypusine synthase: Does Crotalaria possess a functional HSS that still has DHS activity?
    Nurhayati N; Ober D
    Phytochemistry; 2005 Jun; 66(11):1346-57. PubMed ID: 15935411
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spermidine metabolism in parasitic protozoa--a comparison to the situation in prokaryotes, viruses, plants and fungi.
    Kaiser AE; Gottwald AM; Wiersch CS; Maier WA; Seitz HM
    Folia Parasitol (Praha); 2003 Mar; 50(1):3-18. PubMed ID: 12735718
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.