BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 19544580)

  • 1. Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody.
    Sinha S; Zhang L; Duan S; Williams TD; Vlasak J; Ionescu R; Topp EM
    Protein Sci; 2009 Aug; 18(8):1573-84. PubMed ID: 19544580
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping.
    Zhang YT; Hu J; Pace AL; Wong R; Wang YJ; Kao YH
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Aug; 965():65-71. PubMed ID: 24999246
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of IgG1 Fc Deamidation at Asparagine 325 and Its Impact on Antibody-dependent Cell-mediated Cytotoxicity and FcγRIIIa Binding.
    Lu X; Machiesky LA; De Mel N; Du Q; Xu W; Washabaugh M; Jiang XR; Wang J
    Sci Rep; 2020 Jan; 10(1):383. PubMed ID: 31941950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Asparagine deamidation dependence on buffer type, pH, and temperature.
    Pace AL; Wong RL; Zhang YT; Kao YH; Wang YJ
    J Pharm Sci; 2013 Jun; 102(6):1712-1723. PubMed ID: 23568760
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo deamidation characterization of monoclonal antibody by LC/MS/MS.
    Huang L; Lu J; Wroblewski VJ; Beals JM; Riggin RM
    Anal Chem; 2005 Mar; 77(5):1432-9. PubMed ID: 15732928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.
    Yan B; Steen S; Hambly D; Valliere-Douglass J; Vanden Bos T; Smallwood S; Yates Z; Arroll T; Han Y; Gadgil H; Latypov RF; Wallace A; Lim A; Kleemann GR; Wang W; Balland A
    J Pharm Sci; 2009 Oct; 98(10):3509-21. PubMed ID: 19475547
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies.
    Furlong MT; Ouyang Z; Wu S; Tamura J; Olah T; Tymiak A; Jemal M
    Biomed Chromatogr; 2012 Aug; 26(8):1024-32. PubMed ID: 22623136
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of deamidation and isomerization sites on pharmaceutical recombinant antibody using H(2)(18)O.
    Terashima I; Koga A; Nagai H
    Anal Biochem; 2007 Sep; 368(1):49-60. PubMed ID: 17617368
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures.
    Diepold K; Bomans K; Wiedmann M; Zimmermann B; Petzold A; Schlothauer T; Mueller R; Moritz B; Stracke JO; Mølhøj M; Reusch D; Bulau P
    PLoS One; 2012; 7(1):e30295. PubMed ID: 22272329
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Independent highly sensitive characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS.
    Gahoual R; Beck A; François YN; Leize-Wagner E
    J Mass Spectrom; 2016 Feb; 51(2):150-8. PubMed ID: 26889931
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles-Part 2: Mass spectrometric methods.
    Reusch D; Haberger M; Falck D; Peter B; Maier B; Gassner J; Hook M; Wagner K; Bonnington L; Bulau P; Wuhrer M
    MAbs; 2015; 7(4):732-42. PubMed ID: 25996192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rate of Asparagine Deamidation in a Monoclonal Antibody Correlating with Hydrogen Exchange Rate at Adjacent Downstream Residues.
    Phillips JJ; Buchanan A; Andrews J; Chodorge M; Sridharan S; Mitchell L; Burmeister N; Kippen AD; Vaughan TJ; Higazi DR; Lowe D
    Anal Chem; 2017 Feb; 89(4):2361-2368. PubMed ID: 28194941
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure Based Prediction of Asparagine Deamidation Propensity in Monoclonal Antibodies.
    Yan Q; Huang M; Lewis MJ; Hu P
    MAbs; 2018; 10(6):901-912. PubMed ID: 29958069
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Traces of pFc' in IVIG interact with human IgG Fc domains and counteract aggregation.
    Rispens T; Himly M; Ooievaar-De Heer P; den Bleker TH; Aalberse RC
    Eur J Pharm Sci; 2010 Apr; 40(1):62-8. PubMed ID: 20211252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glutamine deamidation of a recombinant monoclonal antibody.
    Liu H; Gaza-Bulseco G; Chumsae C
    Rapid Commun Mass Spectrom; 2008 Dec; 22(24):4081-8. PubMed ID: 19021137
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human antibody Fc deamidation in vivo.
    Liu YD; van Enk JZ; Flynn GC
    Biologicals; 2009 Oct; 37(5):313-22. PubMed ID: 19608432
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Degradation products analysis of an Fc fusion protein using LC/MS methods.
    Ren D; Ratnaswamy G; Beierle J; Treuheit MJ; Brems DN; Bondarenko PV
    Int J Biol Macromol; 2009 Jan; 44(1):81-5. PubMed ID: 19014964
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles--part 1: separation-based methods.
    Reusch D; Haberger M; Maier B; Maier M; Kloseck R; Zimmermann B; Hook M; Szabo Z; Tep S; Wegstein J; Alt N; Bulau P; Wuhrer M
    MAbs; 2015; 7(1):167-79. PubMed ID: 25524468
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis.
    Gadgil HS; Bondarenko PV; Pipes GD; Dillon TM; Banks D; Abel J; Kleemann GR; Treuheit MJ
    Anal Biochem; 2006 Aug; 355(2):165-74. PubMed ID: 16828048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assessment method for deamidation in proteins using carboxylic acid derivatization-liquid chromatography-tandem mass spectrometry.
    Kawasue S; Sakaguchi Y; Koga R; Yoshida H; Nohta H
    J Pharm Biomed Anal; 2020 Mar; 181():113095. PubMed ID: 31962249
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.