BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 19546476)

  • 1. Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
    Fandy TE; Herman JG; Kerns P; Jiemjit A; Sugar EA; Choi SH; Yang AS; Aucott T; Dauses T; Odchimar-Reissig R; Licht J; McConnell MJ; Nasrallah C; Kim MK; Zhang W; Sun Y; Murgo A; Espinoza-Delgado I; Oteiza K; Owoeye I; Silverman LR; Gore SD; Carraway HE
    Blood; 2009 Sep; 114(13):2764-73. PubMed ID: 19546476
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand up 2 cancer study.
    Azad NS; El-Khoueiry A; Yin J; Oberg AL; Flynn P; Adkins D; Sharma A; Weisenberger DJ; Brown T; Medvari P; Jones PA; Easwaran H; Kamel I; Bahary N; Kim G; Picus J; Pitot HC; Erlichman C; Donehower R; Shen H; Laird PW; Piekarz R; Baylin S; Ahuja N
    Oncotarget; 2017 May; 8(21):35326-35338. PubMed ID: 28186961
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms.
    Gore SD; Baylin S; Sugar E; Carraway H; Miller CB; Carducci M; Grever M; Galm O; Dauses T; Karp JE; Rudek MA; Zhao M; Smith BD; Manning J; Jiemjit A; Dover G; Mays A; Zwiebel J; Murgo A; Weng LJ; Herman JG
    Cancer Res; 2006 Jun; 66(12):6361-9. PubMed ID: 16778214
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.
    Prebet T; Sun Z; Figueroa ME; Ketterling R; Melnick A; Greenberg PL; Herman J; Juckett M; Smith MR; Malick L; Paietta E; Czader M; Litzow M; Gabrilove J; Erba HP; Gore SD; Tallman MS
    J Clin Oncol; 2014 Apr; 32(12):1242-8. PubMed ID: 24663049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Azacitidine with or without Entinostat for the treatment of therapy-related myeloid neoplasm: further results of the E1905 North American Leukemia Intergroup study.
    Prebet T; Sun Z; Ketterling RP; Zeidan A; Greenberg P; Herman J; Juckett M; Smith MR; Malick L; Paietta E; Czader M; Figueroa M; Gabrilove J; Erba HP; Tallman MS; Litzow M; Gore SD;
    Br J Haematol; 2016 Feb; 172(3):384-91. PubMed ID: 26577691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation.
    Figueroa ME; Skrabanek L; Li Y; Jiemjit A; Fandy TE; Paietta E; Fernandez H; Tallman MS; Greally JM; Carraway H; Licht JD; Gore SD; Melnick A
    Blood; 2009 Oct; 114(16):3448-58. PubMed ID: 19652201
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies.
    Abaza YM; Kadia TM; Jabbour EJ; Konopleva MY; Borthakur G; Ferrajoli A; Estrov Z; Wierda WG; Alfonso A; Chong TH; Chuah C; Koh LP; Goh BC; Chang JE; Durkes DE; Foudray MC; Kantarjian HM; Dong XQ; Garcia-Manero G
    Cancer; 2017 Dec; 123(24):4851-4859. PubMed ID: 28841236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms and potential molecular markers of early response to combination epigenetic therapy in patients with myeloid malignancies.
    Liu HB; Urbanavicius D; Tan P; Spencer A; Dear AE
    Int J Oncol; 2014 Oct; 45(4):1742-8. PubMed ID: 25051119
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS.
    Leone G; Voso MT; Teofili L; Lübbert M
    Clin Immunol; 2003 Oct; 109(1):89-102. PubMed ID: 14585280
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome.
    Tellez CS; Grimes MJ; Picchi MA; Liu Y; March TH; Reed MD; Oganesian A; Taverna P; Belinsky SA
    Int J Cancer; 2014 Nov; 135(9):2223-31. PubMed ID: 24668305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study.
    Connolly RM; Li H; Jankowitz RC; Zhang Z; Rudek MA; Jeter SC; Slater SA; Powers P; Wolff AC; Fetting JH; Brufsky A; Piekarz R; Ahuja N; Laird PW; Shen H; Weisenberger DJ; Cope L; Herman JG; Somlo G; Garcia AA; Jones PA; Baylin SB; Davidson NE; Zahnow CA; Stearns V
    Clin Cancer Res; 2017 Jun; 23(11):2691-2701. PubMed ID: 27979916
    [No Abstract]   [Full Text] [Related]  

  • 12. Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine.
    Ahrens TD; Timme S; Hoeppner J; Ostendorp J; Hembach S; Follo M; Hopt UT; Werner M; Busch H; Boerries M; Lassmann S
    Epigenetics; 2015; 10(5):431-45. PubMed ID: 25923331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.
    Juergens RA; Wrangle J; Vendetti FP; Murphy SC; Zhao M; Coleman B; Sebree R; Rodgers K; Hooker CM; Franco N; Lee B; Tsai S; Delgado IE; Rudek MA; Belinsky SA; Herman JG; Baylin SB; Brock MV; Rudin CM
    Cancer Discov; 2011 Dec; 1(7):598-607. PubMed ID: 22586682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers.
    Diesch J; Zwick A; Garz AK; Palau A; Buschbeck M; Götze KS
    Clin Epigenetics; 2016; 8():71. PubMed ID: 27330573
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.
    Belinsky SA; Grimes MJ; Picchi MA; Mitchell HD; Stidley CA; Tesfaigzi Y; Channell MM; Liu Y; Casero RA; Baylin SB; Reed MD; Tellez CS; March TH
    Cancer Res; 2011 Jan; 71(2):454-62. PubMed ID: 21224363
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model.
    Reed MD; Tellez CS; Grimes MJ; Picchi MA; Tessema M; Cheng YS; March TH; Kuehl PJ; Belinsky SA
    Br J Cancer; 2013 Oct; 109(7):1775-81. PubMed ID: 24045660
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents.
    Claus R; Almstedt M; Lübbert M
    Semin Oncol; 2005 Oct; 32(5):511-20. PubMed ID: 16210092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extended dosing with CC-486 (oral azacitidine) in patients with myeloid malignancies.
    Savona MR; Kolibaba K; Conkling P; Kingsley EC; Becerra C; Morris JC; Rifkin RM; Laille E; Kellerman A; Ukrainskyj SM; Dong Q; Skikne BS
    Am J Hematol; 2018 Oct; 93(10):1199-1206. PubMed ID: 30016552
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phase I Study of Epigenetic Priming with Azacitidine Prior to Standard Neoadjuvant Chemotherapy for Patients with Resectable Gastric and Esophageal Adenocarcinoma: Evidence of Tumor Hypomethylation as an Indicator of Major Histopathologic Response.
    Schneider BJ; Shah MA; Klute K; Ocean A; Popa E; Altorki N; Lieberman M; Schreiner A; Yantiss R; Christos PJ; Palmer R; You D; Viale A; Kermani P; Scandura JM
    Clin Cancer Res; 2017 Jun; 23(11):2673-2680. PubMed ID: 27836862
    [No Abstract]   [Full Text] [Related]  

  • 20. Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes.
    Press KR; Uy N; Keefer J; Gore SD; Carraway HE; Sakoian S; Prebet T
    Leuk Lymphoma; 2018 Mar; 59(3):755-757. PubMed ID: 28738707
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 16.