BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 19547925)

  • 1. Comparative homology modeling-inspired protein engineering for improvement of catalytic activity of Mugil cephalus epoxide hydrolase.
    Choi SH; Kim HS; Lee EY
    Biotechnol Lett; 2009 Oct; 31(10):1617-24. PubMed ID: 19547925
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cloning of an epoxide hydrolase-encoding gene from Aspergillus niger M200, overexpression in E. coli, and modification of activity and enantioselectivity of the enzyme by protein engineering.
    Kotik M; Stepánek V; Kyslík P; Maresová H
    J Biotechnol; 2007 Oct; 132(1):8-15. PubMed ID: 17875334
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish, Mugil cephalus.
    Lee SJ; Kim HS; Kim SJ; Park S; Kim BJ; Shuler ML; Lee EY
    Biotechnol Lett; 2007 Feb; 29(2):237-46. PubMed ID: 17151961
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional expression and magnetic nanoparticle-based Immobilization of a protein-engineered marine fish epoxide hydrolase of Mugil cephalus for enantioselective hydrolysis of racemic styrene oxide.
    Choi SH; Kim HS; Lee IS; Lee EY
    Biotechnol Lett; 2010 Nov; 32(11):1685-91. PubMed ID: 20574831
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cloning, expression, purification, and characterization of a novel epoxide hydrolase from Aspergillus niger SQ-6.
    Liu Y; Wu S; Wang J; Yang L; Sun W
    Protein Expr Purif; 2007 Jun; 53(2):239-46. PubMed ID: 17317214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Active site of epoxide hydrolases revisited: a noncanonical residue in potato StEH1 promotes both formation and breakdown of the alkylenzyme intermediate.
    Thomaeus A; Carlsson J; Aqvist J; Widersten M
    Biochemistry; 2007 Mar; 46(9):2466-79. PubMed ID: 17284015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase.
    Arand M; Hemmer H; Dürk H; Baratti J; Archelas A; Furstoss R; Oesch F
    Biochem J; 1999 Nov; 344 Pt 1(Pt 1):273-80. PubMed ID: 10548561
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modelling of human microsomal epoxide hydrolase (EH) by homology with a fungal (Aspergillus niger) EH crystal structure of 1.8 A resolution: structure-activity relationships in epoxides inhibiting EH activity.
    Lewis DF; Lake BG; Bird MG
    Toxicol In Vitro; 2005 Jun; 19(4):517-22. PubMed ID: 15826809
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Laboratory evolution of an epoxide hydrolase - towards an enantioconvergent biocatalyst.
    Kotik M; Archelas A; Faměrová V; Oubrechtová P; Křen V
    J Biotechnol; 2011 Oct; 156(1):1-10. PubMed ID: 21854816
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate.
    Arand M; Müller F; Mecky A; Hinz W; Urban P; Pompon D; Kellner R; Oesch F
    Biochem J; 1999 Jan; 337 ( Pt 1)(Pt 1):37-43. PubMed ID: 9854022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm.
    Feng X; Sanchis J; Reetz MT; Rabitz H
    Chemistry; 2012 Apr; 18(18):5646-54. PubMed ID: 22434591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular engineering of epoxide hydrolase and its application to asymmetric and enantioconvergent hydrolysis.
    Lee EY; Shuler ML
    Biotechnol Bioeng; 2007 Oct; 98(2):318-27. PubMed ID: 17405175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure and function of 2,3-dimethylmalate lyase, a PEP mutase/isocitrate lyase superfamily member.
    Narayanan B; Niu W; Joosten HJ; Li Z; Kuipers RK; Schaap PJ; Dunaway-Mariano D; Herzberg O
    J Mol Biol; 2009 Feb; 386(2):486-503. PubMed ID: 19133276
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fungal epoxide hydrolases: new landmarks in sequence-activity space.
    Smit MS
    Trends Biotechnol; 2004 Mar; 22(3):123-9. PubMed ID: 15036862
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Converting an esterase into an epoxide hydrolase.
    Jochens H; Stiba K; Savile C; Fujii R; Yu JG; Gerassenkov T; Kazlauskas RJ; Bornscheuer UT
    Angew Chem Int Ed Engl; 2009; 48(19):3532-5. PubMed ID: 19350592
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequence and structure of epoxide hydrolases: a systematic analysis.
    Barth S; Fischer M; Schmid RD; Pleiss J
    Proteins; 2004 Jun; 55(4):846-55. PubMed ID: 15146483
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution.
    Reetz MT; Torre C; Eipper A; Lohmer R; Hermes M; Brunner B; Maichele A; Bocola M; Arand M; Cronin A; Genzel Y; Archelas A; Furstoss R
    Org Lett; 2004 Jan; 6(2):177-80. PubMed ID: 14723522
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Semifunctional site-specific mutants affecting the hydrolytic half-reaction of microsomal epoxide hydrolase.
    Tzeng HF; Laughlin LT; Armstrong RN
    Biochemistry; 1998 Mar; 37(9):2905-11. PubMed ID: 9485442
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An insect juvenile hormone-specific epoxide hydrolase is related to vertebrate microsomal epoxide hydrolases.
    Wojtasek H; Prestwich GD
    Biochem Biophys Res Commun; 1996 Mar; 220(2):323-9. PubMed ID: 8645304
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Homology modelling and site-directed mutagenesis studies of the epoxide hydrolase from Phanerochaete chrysosporium.
    Zhang LF; Wu JM; Feng H
    J Biochem; 2011 Jun; 149(6):673-84. PubMed ID: 21292804
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.