These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Identification and optimization of N3,N6-diaryl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamines as a novel class of ACK1 inhibitors. Kopecky DJ; Hao X; Chen Y; Fu J; Jiao X; Jaen JC; Cardozo MG; Liu J; Wang Z; Walker NP; Wesche H; Li S; Farrelly E; Xiao SH; Kayser F Bioorg Med Chem Lett; 2008 Dec; 18(24):6352-6. PubMed ID: 18993068 [TBL] [Abstract][Full Text] [Related]
6. Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity. Kirrane TM; Boyer SJ; Burke J; Guo X; Snow RJ; Soleymanzadeh L; Swinamer A; Zhang Y; Madwed JB; Kashem M; Kugler S; O'Neill MM Bioorg Med Chem Lett; 2012 Jan; 22(1):738-42. PubMed ID: 22056746 [TBL] [Abstract][Full Text] [Related]
7. Novel and selective spiroindoline-based inhibitors of Sky kinase. Powell NA; Kohrt JT; Filipski KJ; Kaufman M; Sheehan D; Edmunds JE; Delaney A; Wang Y; Bourbonais F; Lee DY; Schwende F; Sun F; McConnell P; Catana C; Chen H; Ohren J; Perrin LA Bioorg Med Chem Lett; 2012 Jan; 22(1):190-3. PubMed ID: 22119469 [TBL] [Abstract][Full Text] [Related]
8. Benzamides and benzamidines as specific inhibitors of epidermal growth factor receptor and v-Src protein tyrosine kinases. Asano T; Yoshikawa T; Usui T; Yamamoto H; Yamamoto Y; Uehara Y; Nakamura H Bioorg Med Chem; 2004 Jul; 12(13):3529-42. PubMed ID: 15186837 [TBL] [Abstract][Full Text] [Related]
9. Itk kinase inhibitors: initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead. Moriarty KJ; Winters M; Qiao L; Ryan D; DesJarlis R; Robinson D; Cook BN; Kashem MA; Kaplita PV; Liu LH; Farrell TM; Khine HH; King J; Pullen SS; Roth GP; Magolda R; Takahashi H Bioorg Med Chem Lett; 2008 Oct; 18(20):5537-40. PubMed ID: 18819794 [TBL] [Abstract][Full Text] [Related]
10. The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthase. Whitlow M; Adler M; Davey D; Huang Q; Koovakkat S; Parkinson JF; Pham E; Polokoff M; Xu W; Yuan S; Phillips G Bioorg Med Chem Lett; 2007 May; 17(9):2505-8. PubMed ID: 17336523 [TBL] [Abstract][Full Text] [Related]
11. Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide. Uto Y; Ogata T; Harada J; Kiyotsuka Y; Ueno Y; Miyazawa Y; Kurata H; Deguchi T; Watanabe N; Takagi T; Wakimoto S; Okuyama R; Abe M; Kurikawa N; Kawamura S; Yamato M; Osumi J Bioorg Med Chem Lett; 2009 Aug; 19(15):4151-8. PubMed ID: 19540759 [TBL] [Abstract][Full Text] [Related]
13. Design and combinatorial synthesis of a novel kinase-focused library using click chemistry-based fragment assembly. Irie T; Fujii I; Sawa M Bioorg Med Chem Lett; 2012 Jan; 22(1):591-6. PubMed ID: 22104147 [TBL] [Abstract][Full Text] [Related]
14. A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors. Noberini R; De SK; Zhang Z; Wu B; Raveendra-Panickar D; Chen V; Vazquez J; Qin H; Song J; Cosford ND; Pellecchia M; Pasquale EB Chem Biol Drug Des; 2011 Oct; 78(4):667-78. PubMed ID: 21791013 [TBL] [Abstract][Full Text] [Related]
15. EphA3 biology and cancer. Janes PW; Slape CI; Farnsworth RH; Atapattu L; Scott AM; Vail ME Growth Factors; 2014 Dec; 32(6):176-89. PubMed ID: 25391995 [TBL] [Abstract][Full Text] [Related]
16. Pharmacological inhibition of Eph receptors enhances glucose-stimulated insulin secretion from mouse and human pancreatic islets. Jain R; Jain D; Liu Q; Bartosinska B; Wang J; Schumann D; Kauschke SG; Eickelmann P; Piemonti L; Gray NS; Lammert E Diabetologia; 2013 Jun; 56(6):1350-5. PubMed ID: 23475368 [TBL] [Abstract][Full Text] [Related]
17. Identification of novel inhibitors of extracellular signal-regulated kinase 2 based on the structure-based virtual screening. Park H; Bahn YJ; Jeong DG; Woo EJ; Kwon JS; Ryu SE Bioorg Med Chem Lett; 2008 Oct; 18(20):5372-6. PubMed ID: 18835158 [TBL] [Abstract][Full Text] [Related]
18. Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors. Qiao L; Baumann CA; Crysler CS; Ninan NS; Abad MC; Spurlino JC; Desjarlais RL; Kervinen J; Neeper MP; Bayoumy SS; Williams R; Deckman IC; Dasgupta M; Reed RL; Huebert ND; Tomczuk BE; Moriarty KJ Bioorg Med Chem Lett; 2006 Jan; 16(1):123-8. PubMed ID: 16236500 [TBL] [Abstract][Full Text] [Related]