BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

517 related articles for article (PubMed ID: 19556857)

  • 1. Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy.
    Wu YT; Tan HL; Huang Q; Ong CN; Shen HM
    Autophagy; 2009 Aug; 5(6):824-34. PubMed ID: 19556857
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IGF-1 alleviates NMDA-induced excitotoxicity in cultured hippocampal neurons against autophagy via the NR2B/PI3K-AKT-mTOR pathway.
    Wang Y; Wang W; Li D; Li M; Wang P; Wen J; Liang M; Su B; Yin Y
    J Cell Physiol; 2014 Nov; 229(11):1618-29. PubMed ID: 24604717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
    Tsurutani J; West KA; Sayyah J; Gills JJ; Dennis PA
    Cancer Res; 2005 Sep; 65(18):8423-32. PubMed ID: 16166321
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S6K Promotes Dopaminergic Neuronal Differentiation Through PI3K/Akt/mTOR-Dependent Signaling Pathways in Human Neural Stem Cells.
    Lee JE; Lim MS; Park JH; Park CH; Koh HC
    Mol Neurobiol; 2016 Aug; 53(6):3771-3782. PubMed ID: 26143260
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress.
    Huang Q; Wu YT; Tan HL; Ong CN; Shen HM
    Cell Death Differ; 2009 Feb; 16(2):264-77. PubMed ID: 18974775
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells.
    Berrak O; Arisan ED; Obakan-Yerlikaya P; Coker-Gürkan A; Palavan-Unsal N
    Apoptosis; 2016 Oct; 21(10):1158-78. PubMed ID: 27484210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P; Kasprzycka M; Liu X; Marzec M; Robertson ES; Slupianek A; Wasik MA
    Cancer Res; 2005 Sep; 65(17):7800-8. PubMed ID: 16140948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway.
    Li LJ; Chai Y; Guo XJ; Chu SL; Zhang LS
    Mol Med Rep; 2018 Jun; 17(6):7886-7892. PubMed ID: 29620275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel signaling by vitamin A/retinol promotes self renewal of mouse embryonic stem cells by activating PI3K/Akt signaling pathway via insulin-like growth factor-1 receptor.
    Chen L; Khillan JS
    Stem Cells; 2010 Jan; 28(1):57-63. PubMed ID: 19890980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IGFBPrP1 accelerates autophagy and activation of hepatic stellate cells via mutual regulation between H19 and PI3K/AKT/mTOR pathway.
    Huang TJ; Ren JJ; Zhang QQ; Kong YY; Zhang HY; Guo XH; Fan HQ; Liu LX
    Biomed Pharmacother; 2019 Aug; 116():109034. PubMed ID: 31152924
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ERK1/2 is involved in luteal cell autophagy regulation during corpus luteum regression via an mTOR-independent pathway.
    Choi J; Jo M; Lee E; Choi D
    Mol Hum Reprod; 2014 Oct; 20(10):972-80. PubMed ID: 25107837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
    Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. α-Mangostin inhibits DMBA/TPA-induced skin cancer through inhibiting inflammation and promoting autophagy and apoptosis by regulating PI3K/Akt/mTOR signaling pathway in mice.
    Wang F; Ma H; Liu Z; Huang W; Xu X; Zhang X
    Biomed Pharmacother; 2017 Aug; 92():672-680. PubMed ID: 28582759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative regulation of PI3K/AKT/mTOR axis regulates fibroblast proliferation, apoptosis and autophagy play a vital role in triptolide-induced epidural fibrosis reduction.
    Dai J; Sun Y; Chen D; Zhang Y; Yan L; Li X; Wang J
    Eur J Pharmacol; 2019 Dec; 864():172724. PubMed ID: 31600493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
    Lu X; Fan Q; Xu L; Li L; Yue Y; Xu Y; Su Y; Zhang D; Wang L
    PLoS One; 2015; 10(2):e0117400. PubMed ID: 25689721
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target.
    Yin Y; Dang W; Zhou X; Xu L; Wang W; Cao W; Chen S; Su J; Cai X; Xiao S; Peppelenbosch MP; Pan Q
    Virulence; 2018 Jan; 9(1):83-98. PubMed ID: 28475412
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy of articular chondrocytes and attenuates inflammatory response in rats with osteoarthritis.
    Xue JF; Shi ZM; Zou J; Li XL
    Biomed Pharmacother; 2017 May; 89():1252-1261. PubMed ID: 28320092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A; Rescan C; Gilot D; Loyer P; Guguen-Guillouzo C; Baffet G
    Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D; Hideshima T; Rodig S; Santo L; Pozzi S; Vallet S; Ikeda H; Perrone G; Gorgun G; Patel K; Desai N; Sportelli P; Kapoor S; Vali S; Mukherjee S; Munshi NC; Anderson KC; Raje N
    Mol Cancer Ther; 2010 Apr; 9(4):963-75. PubMed ID: 20371718
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.