These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

519 related articles for article (PubMed ID: 19556857)

  • 1. Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy.
    Wu YT; Tan HL; Huang Q; Ong CN; Shen HM
    Autophagy; 2009 Aug; 5(6):824-34. PubMed ID: 19556857
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IGF-1 alleviates NMDA-induced excitotoxicity in cultured hippocampal neurons against autophagy via the NR2B/PI3K-AKT-mTOR pathway.
    Wang Y; Wang W; Li D; Li M; Wang P; Wen J; Liang M; Su B; Yin Y
    J Cell Physiol; 2014 Nov; 229(11):1618-29. PubMed ID: 24604717
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
    Tsurutani J; West KA; Sayyah J; Gills JJ; Dennis PA
    Cancer Res; 2005 Sep; 65(18):8423-32. PubMed ID: 16166321
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S6K Promotes Dopaminergic Neuronal Differentiation Through PI3K/Akt/mTOR-Dependent Signaling Pathways in Human Neural Stem Cells.
    Lee JE; Lim MS; Park JH; Park CH; Koh HC
    Mol Neurobiol; 2016 Aug; 53(6):3771-3782. PubMed ID: 26143260
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress.
    Huang Q; Wu YT; Tan HL; Ong CN; Shen HM
    Cell Death Differ; 2009 Feb; 16(2):264-77. PubMed ID: 18974775
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells.
    Berrak O; Arisan ED; Obakan-Yerlikaya P; Coker-Gürkan A; Palavan-Unsal N
    Apoptosis; 2016 Oct; 21(10):1158-78. PubMed ID: 27484210
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P; Kasprzycka M; Liu X; Marzec M; Robertson ES; Slupianek A; Wasik MA
    Cancer Res; 2005 Sep; 65(17):7800-8. PubMed ID: 16140948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of endoplasmic reticulum stress on autophagy and apoptosis of human leukemia cells via inhibition of the PI3K/AKT/mTOR signaling pathway.
    Li LJ; Chai Y; Guo XJ; Chu SL; Zhang LS
    Mol Med Rep; 2018 Jun; 17(6):7886-7892. PubMed ID: 29620275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel signaling by vitamin A/retinol promotes self renewal of mouse embryonic stem cells by activating PI3K/Akt signaling pathway via insulin-like growth factor-1 receptor.
    Chen L; Khillan JS
    Stem Cells; 2010 Jan; 28(1):57-63. PubMed ID: 19890980
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IGFBPrP1 accelerates autophagy and activation of hepatic stellate cells via mutual regulation between H19 and PI3K/AKT/mTOR pathway.
    Huang TJ; Ren JJ; Zhang QQ; Kong YY; Zhang HY; Guo XH; Fan HQ; Liu LX
    Biomed Pharmacother; 2019 Aug; 116():109034. PubMed ID: 31152924
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ERK1/2 is involved in luteal cell autophagy regulation during corpus luteum regression via an mTOR-independent pathway.
    Choi J; Jo M; Lee E; Choi D
    Mol Hum Reprod; 2014 Oct; 20(10):972-80. PubMed ID: 25107837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
    Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
    [TBL] [Abstract][Full Text] [Related]  

  • 14. α-Mangostin inhibits DMBA/TPA-induced skin cancer through inhibiting inflammation and promoting autophagy and apoptosis by regulating PI3K/Akt/mTOR signaling pathway in mice.
    Wang F; Ma H; Liu Z; Huang W; Xu X; Zhang X
    Biomed Pharmacother; 2017 Aug; 92():672-680. PubMed ID: 28582759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative regulation of PI3K/AKT/mTOR axis regulates fibroblast proliferation, apoptosis and autophagy play a vital role in triptolide-induced epidural fibrosis reduction.
    Dai J; Sun Y; Chen D; Zhang Y; Yan L; Li X; Wang J
    Eur J Pharmacol; 2019 Dec; 864():172724. PubMed ID: 31600493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
    Lu X; Fan Q; Xu L; Li L; Yue Y; Xu Y; Su Y; Zhang D; Wang L
    PLoS One; 2015; 10(2):e0117400. PubMed ID: 25689721
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target.
    Yin Y; Dang W; Zhou X; Xu L; Wang W; Cao W; Chen S; Su J; Cai X; Xiao S; Peppelenbosch MP; Pan Q
    Virulence; 2018 Jan; 9(1):83-98. PubMed ID: 28475412
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy of articular chondrocytes and attenuates inflammatory response in rats with osteoarthritis.
    Xue JF; Shi ZM; Zou J; Li XL
    Biomed Pharmacother; 2017 May; 89():1252-1261. PubMed ID: 28320092
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A; Rescan C; Gilot D; Loyer P; Guguen-Guillouzo C; Baffet G
    Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D; Hideshima T; Rodig S; Santo L; Pozzi S; Vallet S; Ikeda H; Perrone G; Gorgun G; Patel K; Desai N; Sportelli P; Kapoor S; Vali S; Mukherjee S; Munshi NC; Anderson KC; Raje N
    Mol Cancer Ther; 2010 Apr; 9(4):963-75. PubMed ID: 20371718
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.