BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 19557250)

  • 1. Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters.
    Andersen J; Kristensen AS; Bang-Andersen B; Strømgaard K
    Chem Commun (Camb); 2009 Jul; (25):3677-92. PubMed ID: 19557250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
    Park JE; Song C; Choi K; Sim T; Moon B; Roh EJ
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5515-8. PubMed ID: 24012181
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters.
    Andersen J; Stuhr-Hansen N; Zachariassen L; Toubro S; Hansen SM; Eildal JN; Bond AD; Bøgesø KP; Bang-Andersen B; Kristensen AS; Strømgaard K
    Proc Natl Acad Sci U S A; 2011 Jul; 108(29):12137-42. PubMed ID: 21730142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
    Dutta AK; Santra S; Sharma H; Voshavar C; Xu L; Mabrouk O; Antonio T; Reith ME
    PLoS One; 2014; 9(11):e113420. PubMed ID: 25427177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Emerging structure-function relationships defining monoamine NSS transporter substrate and ligand affinity.
    Wang CI; Lewis RJ
    Biochem Pharmacol; 2010 Apr; 79(8):1083-91. PubMed ID: 19954741
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.
    Pechulis AD; Beck JP; Curry MA; Wolf MA; Harms AE; Xi N; Opalka C; Sweet MP; Yang Z; Vellekoop AS; Klos AM; Crocker PJ; Hassler C; Laws M; Kitchen DB; Smith MA; Olson RE; Liu S; Molino BF
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7219-22. PubMed ID: 23084899
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (Prozac).
    Andersen J; Stuhr-Hansen N; Zachariassen LG; Koldsø H; Schiøtt B; Strømgaard K; Kristensen AS
    Mol Pharmacol; 2014 May; 85(5):703-14. PubMed ID: 24516100
    [TBL] [Abstract][Full Text] [Related]  

  • 8. D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.
    Dutta AK; Ghosh B; Biswas S; Reith ME
    Eur J Pharmacol; 2008 Jul; 589(1-3):73-9. PubMed ID: 18561912
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Putative drug binding conformations of monoamine transporters.
    Ravna AW; Sylte I; Kristiansen K; Dahl SG
    Bioorg Med Chem; 2006 Feb; 14(3):666-75. PubMed ID: 16216517
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for action by diverse antidepressants on biogenic amine transporters.
    Wang H; Goehring A; Wang KH; Penmatsa A; Ressler R; Gouaux E
    Nature; 2013 Nov; 503(7474):141-5. PubMed ID: 24121440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Monoamine transporters: structure, intrinsic dynamics and allosteric regulation.
    Cheng MH; Bahar I
    Nat Struct Mol Biol; 2019 Jul; 26(7):545-556. PubMed ID: 31270469
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy.
    Daws LC
    Pharmacol Ther; 2009 Jan; 121(1):89-99. PubMed ID: 19022290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Further structure-activity relationship studies of piperidine-based monoamine transporter inhibitors: effects of piperidine ring stereochemistry on potency. Identification of norepinephrine transporter selective ligands and broad-spectrum transporter inhibitors.
    He R; Kurome T; Giberson KM; Johnson KM; Kozikowski AP
    J Med Chem; 2005 Dec; 48(25):7970-9. PubMed ID: 16335921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors.
    Mahaney PE; Kim CY; Coghlan RD; Cohn ST; Heffernan GD; Huselton CA; Terefenko EA; Vu AT; Zhang P; Burroughs KD; Cosmi SA; Bray JA; Johnston GH; Deecher DC; Trybulski EJ
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5807-10. PubMed ID: 19713106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of 4-benzylpiperidine carboxamides as dual serotonin and norepinephrine reuptake inhibitors.
    Paudel S; Cao Y; Guo S; An B; Kim KM; Cheon SH
    Bioorg Med Chem; 2015 Oct; 23(19):6418-26. PubMed ID: 26337019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Orjales A; Mosquera R; Toledo A; Pumar MC; García N; Cortizo L; Labeaga L; Innerárity A
    J Med Chem; 2003 Dec; 46(25):5512-32. PubMed ID: 14640559
    [TBL] [Abstract][Full Text] [Related]  

  • 17. From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies.
    Eildal JN; Andersen J; Kristensen AS; Jørgensen AM; Bang-Andersen B; Jørgensen M; Strømgaard K
    J Med Chem; 2008 May; 51(10):3045-8. PubMed ID: 18429609
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative modeling of the human monoamine transporters: similarities in substrate binding.
    Koldsø H; Christiansen AB; Sinning S; Schiøtt B
    ACS Chem Neurosci; 2013 Feb; 4(2):295-309. PubMed ID: 23421681
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coordination of Na(+) by monoamine ligands in dopamine, norepinephrine, and serotonin transporters.
    Xhaard H; Backström V; Denessiouk K; Johnson MS
    J Chem Inf Model; 2008 Jul; 48(7):1423-37. PubMed ID: 18543980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.
    Zhou Z; Zhen J; Karpowich NK; Goetz RM; Law CJ; Reith ME; Wang DN
    Science; 2007 Sep; 317(5843):1390-3. PubMed ID: 17690258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.