220 related articles for article (PubMed ID: 19558188)
21. The environmental pollutant 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene induces rat hepatic cytochrome P450 2B and 3A expression through the constitutive androstane receptor and pregnane X receptor.
Wyde ME; Bartolucci E; Ueda A; Zhang H; Yan B; Negishi M; You L
Mol Pharmacol; 2003 Aug; 64(2):474-81. PubMed ID: 12869653
[TBL] [Abstract][Full Text] [Related]
22. The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes.
Howe K; Sanat F; Thumser AE; Coleman T; Plant N
Xenobiotica; 2011 Jul; 41(7):519-29. PubMed ID: 21476904
[TBL] [Abstract][Full Text] [Related]
23. Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR).
Chang TK; Waxman DJ
Drug Metab Rev; 2006; 38(1-2):51-73. PubMed ID: 16684648
[TBL] [Abstract][Full Text] [Related]
24. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
Zhang H; LeCulyse E; Liu L; Hu M; Matoney L; Zhu W; Yan B
Arch Biochem Biophys; 1999 Aug; 368(1):14-22. PubMed ID: 10415106
[TBL] [Abstract][Full Text] [Related]
25. Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).
van de Steeg E; van der Kruijssen CM; Wagenaar E; Burggraaff JE; Mesman E; Kenworthy KE; Schinkel AH
Drug Metab Dispos; 2009 Feb; 37(2):277-81. PubMed ID: 19022939
[TBL] [Abstract][Full Text] [Related]
26. Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes.
Dvorák Z; Maurel P; Vilarem MJ; Ulrichová J; Modrianský M
Cell Biol Toxicol; 2007 Mar; 23(2):63-73. PubMed ID: 16964586
[TBL] [Abstract][Full Text] [Related]
27. Targeting xenobiotic receptors PXR and CAR for metabolic diseases.
Gao J; Xie W
Trends Pharmacol Sci; 2012 Oct; 33(10):552-8. PubMed ID: 22889594
[TBL] [Abstract][Full Text] [Related]
28. Lack of association of single-nucleotide polymorphisms in pregnane X receptor, hepatic nuclear factor 4alpha, and constitutive androstane receptor with docetaxel pharmacokinetics.
Tham LS; Holford NH; Hor SY; Tan T; Wang L; Lim RC; Lee HS; Lee SC; Goh BC
Clin Cancer Res; 2007 Dec; 13(23):7126-32. PubMed ID: 18056193
[TBL] [Abstract][Full Text] [Related]
29. 3D structures and ligand specificities of nuclear xenobiotic receptors CAR, PXR and VDR.
Wu B; Li S; Dong D
Drug Discov Today; 2013 Jun; 18(11-12):574-81. PubMed ID: 23299080
[TBL] [Abstract][Full Text] [Related]
30. Polymorphisms in regulators of xenobiotic transport and metabolism genes PXR and CAR do not affect multiple myeloma risk: a case-control study in the context of the IMMEnSE consortium.
Martino A; Sainz J; Manuel Reis R; Moreno V; Buda G; Lesueur F; Marques H; García-Sanz R; Ríos R; Stein A; Dumontet C; Gemignani F; Maria Rossi A; Landi S; Jurado M; Petrini M; Jamroziak K; Campa D; Canzian F
J Hum Genet; 2013 Mar; 58(3):155-9. PubMed ID: 23303387
[TBL] [Abstract][Full Text] [Related]
31. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
Küblbeck J; Zancanella V; Prantner V; Molnár F; Squires EJ; Dacasto M; Honkakoski P; Giantin M
Xenobiotica; 2016; 46(3):200-10. PubMed ID: 26153444
[TBL] [Abstract][Full Text] [Related]
32. Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.
Koenen A; Kroemer HK; Grube M; Meyer zu Schwabedissen HE
Expert Rev Clin Pharmacol; 2011 Nov; 4(6):729-42. PubMed ID: 22111859
[TBL] [Abstract][Full Text] [Related]
33. Molecular mechanisms of drug transporter regulation.
Tirona RG
Handb Exp Pharmacol; 2011; (201):373-402. PubMed ID: 21103976
[TBL] [Abstract][Full Text] [Related]
34. Targeting xenobiotic receptors PXR and CAR in human diseases.
Banerjee M; Robbins D; Chen T
Drug Discov Today; 2015 May; 20(5):618-28. PubMed ID: 25463033
[TBL] [Abstract][Full Text] [Related]
35. Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms.
König J
Handb Exp Pharmacol; 2011; (201):1-28. PubMed ID: 21103967
[TBL] [Abstract][Full Text] [Related]
36. [Advances in the study of organic anion transporting polypeptide 1B3].
Li X; Li Y
Yao Xue Xue Bao; 2011 Nov; 46(11):1279-85. PubMed ID: 22260016
[TBL] [Abstract][Full Text] [Related]
37. The regulation of human hepatic drug transporter expression by activation of xenobiotic-sensing nuclear receptors.
Amacher DE
Expert Opin Drug Metab Toxicol; 2016 Dec; 12(12):1463-1477. PubMed ID: 27548410
[TBL] [Abstract][Full Text] [Related]
38. Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation.
Tirona RG; Leake BF; Wolkoff AW; Kim RB
J Pharmacol Exp Ther; 2003 Jan; 304(1):223-8. PubMed ID: 12490595
[TBL] [Abstract][Full Text] [Related]
39. Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors.
Rouquié D; Tinwell H; Blanck O; Schorsch F; Geter D; Wason S; Bars R
Regul Toxicol Pharmacol; 2014 Dec; 70(3):673-80. PubMed ID: 25455223
[TBL] [Abstract][Full Text] [Related]
40. Small-molecule modulators of PXR and CAR.
Chai SC; Cherian MT; Wang YM; Chen T
Biochim Biophys Acta; 2016 Sep; 1859(9):1141-1154. PubMed ID: 26921498
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]