232 related articles for article (PubMed ID: 19560264)
1. Rapamycin increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translational inhibition of mdm2 in cancer cells.
Kao CL; Hsu HS; Chen HW; Cheng TH
Cancer Lett; 2009 Dec; 286(2):250-9. PubMed ID: 19560264
[TBL] [Abstract][Full Text] [Related]
2. MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus.
Hsu HS; Chen HW; Kao CL; Wu ML; Li AF; Cheng TH
Ann Surg Oncol; 2011 May; 18(5):1469-77. PubMed ID: 21080085
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of MDM2 Re-Sensitizes Rapamycin Resistant Renal Cancer Cells via the Activation of p53.
Tian X; Dai S; Sun J; Jiang S; Sui C; Meng F; Li Y; Fu L; Jiang T; Wang Y; Su J; Jiang Y
Cell Physiol Biochem; 2016; 39(5):2088-2098. PubMed ID: 27825169
[TBL] [Abstract][Full Text] [Related]
4. MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.
Phillips A; Blaydes JP
Oncogene; 2008 Mar; 27(11):1645-9. PubMed ID: 17828301
[TBL] [Abstract][Full Text] [Related]
5. Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.
Lee SJ; Lim CJ; Min JK; Lee JK; Kim YM; Lee JY; Won MH; Kwon YG
Cell Death Differ; 2007 Jun; 14(6):1106-16. PubMed ID: 17318220
[TBL] [Abstract][Full Text] [Related]
6. Rapamycin inhibits IGF-1-mediated up-regulation of MDM2 and sensitizes cancer cells to chemotherapy.
Du W; Yi Y; Zhang H; Bergholz J; Wu J; Ying H; Zhang Y; Xiao ZX
PLoS One; 2013; 8(4):e63179. PubMed ID: 23638184
[TBL] [Abstract][Full Text] [Related]
7. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis.
Zhang C; Liu J; Tan C; Yue X; Zhao Y; Peng J; Wang X; Laddha SV; Chan CS; Zheng S; Hu W; Feng Z
Oncotarget; 2016 Feb; 7(8):8783-96. PubMed ID: 26840028
[TBL] [Abstract][Full Text] [Related]
8. The identification of an internal ribosomal entry site in the 5'-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage.
Yang DQ; Halaby MJ; Zhang Y
Oncogene; 2006 Aug; 25(33):4613-9. PubMed ID: 16607284
[TBL] [Abstract][Full Text] [Related]
9. A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop.
Xiong L; Kou F; Yang Y; Wu J
J Cell Biol; 2007 Sep; 178(6):995-1007. PubMed ID: 17846171
[TBL] [Abstract][Full Text] [Related]
10. Involvement of p53 in oroxylin A-induced apoptosis in cancer cells.
Mu R; Qi Q; Gu H; Wang J; Yang Y; Rong J; Liu W; Lu N; You Q; Guo Q
Mol Carcinog; 2009 Dec; 48(12):1159-69. PubMed ID: 19626645
[TBL] [Abstract][Full Text] [Related]
11. eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase.
Sundin T; Peffley D; Hentosh P
Exp Cell Res; 2013 Aug; 319(13):2103-2112. PubMed ID: 23747720
[TBL] [Abstract][Full Text] [Related]
12. TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation.
Malaguarnera R; Vella V; Pandini G; Sanfilippo M; Pezzino V; Vigneri R; Frasca F
Mol Cancer Res; 2008 Jan; 6(1):64-77. PubMed ID: 18234963
[TBL] [Abstract][Full Text] [Related]
13. E2F1 inhibits MDM2 expression in a p53-dependent manner.
Tian X; Chen Y; Hu W; Wu M
Cell Signal; 2011 Jan; 23(1):193-200. PubMed ID: 20837136
[TBL] [Abstract][Full Text] [Related]
14. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
Kitagawa M; Aonuma M; Lee SH; Fukutake S; McCormick F
Oncogene; 2008 Sep; 27(40):5303-14. PubMed ID: 18521084
[TBL] [Abstract][Full Text] [Related]
15. Knockdown of FAM3B triggers cell apoptosis through p53-dependent pathway.
Mou H; Li Z; Yao P; Zhuo S; Luan W; Deng B; Qian L; Yang M; Mei H; Le Y
Int J Biochem Cell Biol; 2013 Mar; 45(3):684-91. PubMed ID: 23246487
[TBL] [Abstract][Full Text] [Related]
16. Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer.
Satheesha S; Cookson VJ; Coleman LJ; Ingram N; Madhok B; Hanby AM; Suleman CA; Sabine VS; Macaskill EJ; Bartlett JM; Dixon JM; McElwaine JN; Hughes TA
Mol Cancer; 2011 Feb; 10():19. PubMed ID: 21320304
[TBL] [Abstract][Full Text] [Related]
17. Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53.
Constantinou C; Clemens MJ
Oncogene; 2005 Jul; 24(30):4839-50. PubMed ID: 15897901
[TBL] [Abstract][Full Text] [Related]
18. Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells.
Zhang X; Gu L; Li J; Shah N; He J; Yang L; Hu Q; Zhou M
Cancer Res; 2010 Dec; 70(23):9895-904. PubMed ID: 20935220
[TBL] [Abstract][Full Text] [Related]
19. mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels.
Goudarzi KM; Nistér M; Lindström MS
Cancer Biol Ther; 2014; 15(11):1499-514. PubMed ID: 25482947
[TBL] [Abstract][Full Text] [Related]
20. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]