BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 19560420)

  • 1. Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
    Das R; Mariano J; Tsai YC; Kalathur RC; Kostova Z; Li J; Tarasov SG; McFeeters RL; Altieri AS; Ji X; Byrd RA; Weissman AM
    Mol Cell; 2009 Jun; 34(6):674-85. PubMed ID: 19560420
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
    Das R; Liang YH; Mariano J; Li J; Huang T; King A; Tarasov SG; Weissman AM; Ji X; Byrd RA
    EMBO J; 2013 Sep; 32(18):2504-16. PubMed ID: 23942235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2.
    Chakrabarti KS; Li J; Das R; Byrd RA
    Structure; 2017 May; 25(5):794-805.e5. PubMed ID: 28434917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2.
    Li W; Tu D; Li L; Wollert T; Ghirlando R; Brunger AT; Ye Y
    Proc Natl Acad Sci U S A; 2009 Mar; 106(10):3722-7. PubMed ID: 19223579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site.
    Chen B; Mariano J; Tsai YC; Chan AH; Cohen M; Weissman AM
    Proc Natl Acad Sci U S A; 2006 Jan; 103(2):341-6. PubMed ID: 16407162
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate.
    Li W; Tu D; Brunger AT; Ye Y
    Nature; 2007 Mar; 446(7133):333-7. PubMed ID: 17310145
    [TBL] [Abstract][Full Text] [Related]  

  • 7. gp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains.
    Liu W; Shang Y; Li W
    Sci Rep; 2014 Nov; 4():7138. PubMed ID: 25409783
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.
    Lechtenberg BC; Rajput A; Sanishvili R; Dobaczewska MK; Ware CF; Mace PD; Riedl SJ
    Nature; 2016 Jan; 529(7587):546-50. PubMed ID: 26789245
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and anticancer activity evaluation of irreversible allosteric inhibitors of the ubiquitin-conjugating enzyme Ube2g2.
    Wang C; Shi G; Ji X
    Medchemcomm; 2018 Nov; 9(11):1818-1825. PubMed ID: 30542531
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum.
    Fang S; Ferrone M; Yang C; Jensen JP; Tiwari S; Weissman AM
    Proc Natl Acad Sci U S A; 2001 Dec; 98(25):14422-7. PubMed ID: 11724934
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.
    Smith CE; Tsai YC; Liang YH; Khago D; Mariano J; Li J; Tarasov SG; Gergel E; Tsai B; Villaneuva M; Clapp ME; Magidson V; Chari R; Byrd RA; Ji X; Weissman AM
    PLoS Biol; 2021 Dec; 19(12):e3001474. PubMed ID: 34879065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
    Li S; Liang YH; Mariano J; Metzger MB; Stringer DK; Hristova VA; Li J; Randazzo PA; Tsai YC; Ji X; Weissman AM
    J Biol Chem; 2015 Dec; 290(51):30225-39. PubMed ID: 26475854
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mulan E3 ubiquitin ligase interacts with multiple E2 conjugating enzymes and participates in mitophagy by recruiting GABARAP.
    Ambivero CT; Cilenti L; Main S; Zervos AS
    Cell Signal; 2014 Dec; 26(12):2921-9. PubMed ID: 25224329
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination.
    Metzger MB; Pruneda JN; Klevit RE; Weissman AM
    Biochim Biophys Acta; 2014 Jan; 1843(1):47-60. PubMed ID: 23747565
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
    Campbell SJ; Edwards RA; Leung CC; Neculai D; Hodge CD; Dhe-Paganon S; Glover JN
    J Biol Chem; 2012 Jul; 287(28):23900-10. PubMed ID: 22589545
    [TBL] [Abstract][Full Text] [Related]  

  • 16. (G2)BRinging an E2 to E3.
    Wang J; Schulman BA
    Structure; 2009 Jul; 17(7):916-7. PubMed ID: 19604471
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs.
    Kar G; Keskin O; Nussinov R; Gursoy A
    J Proteome Res; 2012 Feb; 11(2):1196-207. PubMed ID: 22149024
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BIRC7-E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer.
    Dou H; Buetow L; Sibbet GJ; Cameron K; Huang DT
    Nat Struct Mol Biol; 2012 Sep; 19(9):876-83. PubMed ID: 22902369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ubiquitin transfer by a RING E3 ligase occurs from a closed E2~ubiquitin conformation.
    Branigan E; Carlos Penedo J; Hay RT
    Nat Commun; 2020 Jun; 11(1):2846. PubMed ID: 32503993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of a primed RING E3-E2-ubiquitin complex by non-covalent ubiquitin.
    Buetow L; Gabrielsen M; Anthony NG; Dou H; Patel A; Aitkenhead H; Sibbet GJ; Smith BO; Huang DT
    Mol Cell; 2015 Apr; 58(2):297-310. PubMed ID: 25801170
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.