303 related articles for article (PubMed ID: 19560482)
21. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Jain A; Lamark T; Sjøttem E; Larsen KB; Awuh JA; Øvervatn A; McMahon M; Hayes JD; Johansen T
J Biol Chem; 2010 Jul; 285(29):22576-91. PubMed ID: 20452972
[TBL] [Abstract][Full Text] [Related]
22. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway.
Hayes JD; McMahon M; Chowdhry S; Dinkova-Kostova AT
Antioxid Redox Signal; 2010 Dec; 13(11):1713-48. PubMed ID: 20446772
[TBL] [Abstract][Full Text] [Related]
23. Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex.
Baird L; Llères D; Swift S; Dinkova-Kostova AT
Proc Natl Acad Sci U S A; 2013 Sep; 110(38):15259-64. PubMed ID: 23986495
[TBL] [Abstract][Full Text] [Related]
24. Molecular evolution of Keap1. Two Keap1 molecules with distinctive intervening region structures are conserved among fish.
Li L; Kobayashi M; Kaneko H; Nakajima-Takagi Y; Nakayama Y; Yamamoto M
J Biol Chem; 2008 Feb; 283(6):3248-3255. PubMed ID: 18057000
[TBL] [Abstract][Full Text] [Related]
25. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2.
Niture SK; Jaiswal AK
J Biol Chem; 2009 May; 284(20):13856-13868. PubMed ID: 19279002
[TBL] [Abstract][Full Text] [Related]
26. Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy.
Shibata T; Ohta T; Tong KI; Kokubu A; Odogawa R; Tsuta K; Asamura H; Yamamoto M; Hirohashi S
Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13568-73. PubMed ID: 18757741
[TBL] [Abstract][Full Text] [Related]
27. Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3.
Rachakonda G; Xiong Y; Sekhar KR; Stamer SL; Liebler DC; Freeman ML
Chem Res Toxicol; 2008 Mar; 21(3):705-10. PubMed ID: 18251510
[TBL] [Abstract][Full Text] [Related]
28. Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity.
Yamamoto T; Suzuki T; Kobayashi A; Wakabayashi J; Maher J; Motohashi H; Yamamoto M
Mol Cell Biol; 2008 Apr; 28(8):2758-70. PubMed ID: 18268004
[TBL] [Abstract][Full Text] [Related]
29. Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.
Iso T; Suzuki T; Baird L; Yamamoto M
Mol Cell Biol; 2016 Dec; 36(24):3100-3112. PubMed ID: 27697860
[TBL] [Abstract][Full Text] [Related]
30. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
Stępkowski TM; Kruszewski MK
Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
[TBL] [Abstract][Full Text] [Related]
31. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
Lo SC; Hannink M
Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
[TBL] [Abstract][Full Text] [Related]
32. Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications.
Keum YS
Ann N Y Acad Sci; 2011 Jul; 1229():184-9. PubMed ID: 21793854
[TBL] [Abstract][Full Text] [Related]
33. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
Katoh Y; Iida K; Kang MI; Kobayashi A; Mizukami M; Tong KI; McMahon M; Hayes JD; Itoh K; Yamamoto M
Arch Biochem Biophys; 2005 Jan; 433(2):342-50. PubMed ID: 15581590
[TBL] [Abstract][Full Text] [Related]
34. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.
Rada P; Rojo AI; Chowdhry S; McMahon M; Hayes JD; Cuadrado A
Mol Cell Biol; 2011 Mar; 31(6):1121-33. PubMed ID: 21245377
[TBL] [Abstract][Full Text] [Related]
35. Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.
Tong KI; Padmanabhan B; Kobayashi A; Shang C; Hirotsu Y; Yokoyama S; Yamamoto M
Mol Cell Biol; 2007 Nov; 27(21):7511-21. PubMed ID: 17785452
[TBL] [Abstract][Full Text] [Related]
36. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.
Taguchi K; Motohashi H; Yamamoto M
Genes Cells; 2011 Feb; 16(2):123-40. PubMed ID: 21251164
[TBL] [Abstract][Full Text] [Related]
37. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.
Cullinan SB; Gordan JD; Jin J; Harper JW; Diehl JA
Mol Cell Biol; 2004 Oct; 24(19):8477-86. PubMed ID: 15367669
[TBL] [Abstract][Full Text] [Related]
38. Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation.
Hong F; Sekhar KR; Freeman ML; Liebler DC
J Biol Chem; 2005 Sep; 280(36):31768-75. PubMed ID: 15985429
[TBL] [Abstract][Full Text] [Related]
39. CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2.
Kigoshi Y; Fukuda T; Endo T; Hayasaka N; Iemura S; Natsume T; Tsuruta F; Chiba T
Sci Rep; 2015 Aug; 5():12857. PubMed ID: 26238671
[TBL] [Abstract][Full Text] [Related]
40. Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
Zhang Y; Crouch DH; Yamamoto M; Hayes JD
Biochem J; 2006 Nov; 399(3):373-85. PubMed ID: 16872277
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
